TCONS_00060007-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00060007-protein
Unique NameTCONS_00060007-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length339

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00060007-protein ID=TCONS_00060007-protein|Name=TCONS_00060007-protein|organism=Clytia hemisphaerica|type=polypeptide|length=339bp
MIANTLRRQVSKSVRQLSTSSQNNVKVAVLGASGGIGQPLALLLKHSPMV
SHLALYDLAPFTPGVGCDLSHIETIGKVTAHMGPENLDECVKDCSLVLIP
AGMPRKPGMTRDDLFNTNASIAMNLADACARNCPEAVLGIITNPVNSTVP
IAAEVFKKHGVYNPSKILGVTTLDVVRANTFVAELKGLDVSKTNVPVIGG
HSGVTILPLLSQVVPKVSFTDDEIAAMTTRIQNAGTEVVEAKAGAGSATL
SMAYAGARFGFSILEAMNGKKGVVECCYRESSITEASYFATPMLLGPGGA
EKDLGIGDMTDFEKEKLDELMPELKSNIAKGEKFAADNM
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_037759XLOC_037759Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00060007TCONS_00060007Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR022383Lactate/malate_DH_C
IPR010097Malate_DH_type1
IPR001557L-lactate/malate_DH
IPR001236Lactate/malate_DH_N
IPR001252Malate_DH_AS
IPR015955Lactate_DH/Glyco_Ohase_4_C
IPR016040NAD(P)-bd_dom
Vocabulary: Molecular Function
TermDefinition
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060L-malate dehydrogenase activity
GO:0016491oxidoreductase activity
GO:0016615malate dehydrogenase activity
GO:0003824catalytic activity
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0006099tricarboxylic acid cycle
GO:0019752carboxylic acid metabolic process
GO:0006108malate metabolic process
GO:0005975carbohydrate metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0005975 carbohydrate metabolic process
biological_process GO:0019752 carboxylic acid metabolic process
biological_process GO:0006108 malate metabolic process
biological_process GO:0055114 oxidation-reduction process
biological_process GO:0006099 tricarboxylic acid cycle
molecular_function GO:0003824 catalytic activity
molecular_function GO:0030060 L-malate dehydrogenase activity
molecular_function GO:0016615 malate dehydrogenase activity
molecular_function GO:0016491 oxidoreductase activity
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR022383Lactate/malate dehydrogenase, C-terminalPFAMPF02866Ldh_1_Ccoord: 171..334
e-value: 3.1E-51
score: 173.5
IPR010097Malate dehydrogenase, type 1TIGRFAMTIGR01772TIGR01772coord: 26..336
e-value: 1.1E-132
score: 440.1
IPR001557L-lactate/malate dehydrogenasePIRSFPIRSF000102Lac_mal_DHcoord: 21..338
e-value: 2.8E-57
score: 192.1
NoneNo IPR availableGENE3D3.40.50.720coord: 26..171
e-value: 9.2E-41
score: 138.5
NoneNo IPR availableGENE3D3.90.110.10coord: 172..339
e-value: 3.5E-51
score: 173.2
NoneNo IPR availableCDDcd01337MDH_glyoxysomal_mitochondrialcoord: 25..335
e-value: 0.0
score: 552.095
IPR001236Lactate/malate dehydrogenase, N-terminalPFAMPF00056Ldh_1_Ncoord: 25..169
e-value: 3.3E-42
score: 143.8
IPR001252Malate dehydrogenase, active sitePROSITEPS00068MDHcoord: 170..182
IPR015955Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminalSUPERFAMILY56327LDH C-terminal domain-likecoord: 170..335
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 1..169

Blast
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BLAST of TCONS_00060007-protein vs. Swiss-Prot (Human)
Match: MDHM (Malate dehydrogenase, mitochondrial OS=Homo sapiens GN=MDH2 PE=1 SV=3)

HSP 1 Score: 457.218 bits (1175), Expect = 1.459e-162
Identity = 220/332 (66.27%), Postives = 273/332 (82.23%), Query Frame = 0 
Query:    4 NTLRRQVSKSVRQ-LSTSSQNNVKVAVLGASGGIGQPLALLLKHSPMVSHLALYDLAPFTPGVGCDLSHIETIGKVTAHMGPENLDECVKDCSLVLIPAGMPRKPGMTRDDLFNTNASIAMNLADACARNCPEAVLGIITNPVNSTVPIAAEVFKKHGVYNPSKILGVTTLDVVRANTFVAELKGLDVSKTNVPVIGGHSGVTILPLLSQVVPKVSFTDDEIAAMTTRIQNAGTEVVEAKAGAGSATLSMAYAGARFGFSILEAMNGKKGVVECCYRESSITEASYFATPMLLGPGGAEKDLGIGDMTDFEKEKLDELMPELKSNIAKGEKF 334
            + L R  S ++R+  STS+QNN KVAVLGASGGIGQPL+LLLK+SP+VS L LYD+A  TPGV  DLSHIET   V  ++GPE L +C+K C +V+IPAG+PRKPGMTRDDLFNTNA+I   L  ACA++CPEA++ +I NPVNST+PI AEVFKKHGVYNP+KI GVTTLD+VRANTFVAELKGLD ++ NVPVIGGH+G TI+PL+SQ  PKV F  D++ A+T RIQ AGTEVV+AKAGAGSATLSMAYAGARF FS+++AMNGK+GVVEC + +S  TE +YF+TP+LLG  G EK+LGIG ++ FE++ + + +PELK++I KGE F
Sbjct:    3 SALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIA-HTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDF 333
The following BLAST results are available for this feature:
BLAST of TCONS_00060007-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MDHM1.459e-16266.27Malate dehydrogenase, mitochondrial OS=Homo sapien... [more]
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