TCONS_00058725-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00058725-protein
Unique NameTCONS_00058725-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length606

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00058725-protein ID=TCONS_00058725-protein|Name=TCONS_00058725-protein|organism=Clytia hemisphaerica|type=polypeptide|length=606bp
MSTPNSPWRKWSAEEINQQGQPPRYNGEEEENLVFSFSPSSSHRFLTPHG
SSSDQCLLLPKSKTTKDSAQQVSEDMADLISSTSYVPSDGMKVEDLMKSG
TGITYNDFIILPGYIDFGTGDVALNSPLTKKITLKTPFISSPMDTVTESD
MAKTMALLGGIGIIHHNCSIEFQANEVHKVKRFEQGFITDPIVISPSHTV
TDVKNIHKKFGFSGFPVTENGKVGGKLVGIVTNRDVDFISPEDHEKPASE
IMTMKEELTVGRDGITLKEANEILSKSKKGKLPIVDDDFNLVALISRTDL
QKNREYPLASKDSKKQLLVGAAISTHDEDVPRLAALVEAGVDVVVLDSSQ
GNSSFQIERIKEIKAKYPNLEVIAGNVVTAAQAKNLIDAGADGLRVGMGS
GSICITQEVCAVGRPQGTAVFYVSEYARRFGVPCIADGGISNAGHIIKAL
TLGASTVMMGSLLAGTFEAPGEYFYQNGVRLKRYRGMGSLGAMKSKGSQS
RYFVESDKVKVAQGVSGSVEDKGSLFKFIPYLTAGVQHGCQDIGAKSXIP
YLTAGVQHGCQDIGAKSLTSLRSMTYSGQLRVEKRTPSAQREGGVHGLHS
YEKQLF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_036992XLOC_036992Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00058725TCONS_00058725Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000644CBS_dom
IPR013785Aldolase_TIM
IPR001093IMP_DH_GMPRt
IPR005990IMP_DH
IPR015875IMP_DH/GMP_Rdtase_CS
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0003938IMP dehydrogenase activity
GO:0016491oxidoreductase activity
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0006164purine nucleotide biosynthetic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
biological_process GO:0006164 purine nucleotide biosynthetic process
molecular_function GO:0003824 catalytic activity
molecular_function GO:0003938 IMP dehydrogenase activity
molecular_function GO:0016491 oxidoreductase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000644CBS domainSMARTSM00116cbs_1coord: 190..241
e-value: 3.6E-9
score: 46.5
coord: 257..305
e-value: 1.4E-6
score: 37.9
IPR000644CBS domainPFAMPF00571CBScoord: 189..236
e-value: 5.5E-5
score: 23.4
coord: 250..300
e-value: 4.9E-4
score: 20.4
IPR000644CBS domainPROSITEPS51371CBScoord: 252..310
score: 10.837
IPR000644CBS domainPROSITEPS51371CBScoord: 187..246
score: 10.601
NoneNo IPR availableSMARTSM01240IMPDH_2coord: 101..596
e-value: 2.6E-255
score: 864.1
NoneNo IPR availableCDDcd04602CBS_pair_IMPDH_2coord: 188..303
e-value: 1.19802E-52
score: 176.239
NoneNo IPR availableSUPERFAMILY51412Inosine monophosphate dehydrogenase (IMPDH)coord: 316..600
coord: 101..184
NoneNo IPR availableSUPERFAMILY54631CBS-domain paircoord: 188..302
IPR013785Aldolase-type TIM barrelGENE3D3.20.20.70coord: 547..606
e-value: 5.4E-10
score: 38.2
IPR013785Aldolase-type TIM barrelGENE3D3.20.20.70coord: 252..546
e-value: 5.2E-81
score: 272.2
coord: 54..217
e-value: 3.1E-27
score: 95.1
IPR001093IMP dehydrogenase/GMP reductasePFAMPF00478IMPDHcoord: 102..547
e-value: 2.1E-131
score: 438.0
IPR001093IMP dehydrogenase/GMP reductaseCDDcd00381IMPDHcoord: 102..547
e-value: 1.16578E-159
score: 462.372
IPR005990Inosine-5'-monophosphate dehydrogenaseTIGRFAMTIGR01302TIGR01302coord: 102..547
e-value: 7.7E-195
score: 645.9
IPR005990Inosine-5'-monophosphate dehydrogenaseHAMAPMF_01964IMPDHcoord: 102..604
score: 80.302
IPR015875IMP dehydrogenase / GMP reductase, conserved sitePROSITEPS00487IMP_DH_GMP_REDcoord: 394..406

Blast
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BLAST of TCONS_00058725-protein vs. Swiss-Prot (Human)
Match: IMDH1 (Inosine-5'-monophosphate dehydrogenase 1 OS=Homo sapiens GN=IMPDH1 PE=1 SV=2)

HSP 1 Score: 728.013 bits (1878), Expect = 0.000e+0
Identity = 361/534 (67.60%), Postives = 421/534 (78.84%), Query Frame = 0 
Query:   76 MADLISS--TSYVPSDGMKVEDLMKSGTGITYNDFIILPGYIDFGTGDVALNSPLTKKITLKTPFISSPMDTVTESDMAKTMALLGGIGIIHHNCSIEFQANEVHKVKRFEQGFITDPIVISPSHTVTDVKNIHKKFGFSGFPVTENGKVGGKLVGIVTNRDVDFISPEDHEKPASEIMTMKEELTVGRDGITLKEANEILSKSKKGKLPIVDDDFNLVALISRTDLQKNREYPLASKDSKKQLLVGAAISTHDEDVPRLAALVEAGVDVVVLDSSQGNSSFQIERIKEIKAKYPNLEVIAGNVVTAAQAKNLIDAGADGLRVGMGSGSICITQEVCAVGRPQGTAVFYVSEYARRFGVPCIADGGISNAGHIIKALTLGASTVMMGSLLAGTFEAPGEYFYQNGVRLKRYRGMGSLGAM-KSKGSQSRYFVESDKVKVAQGVSGSVEDKGSLFKFIPYLTAGVQHGCQDIGAKSXIPYLTAGVQHGCQDIGAKSLTSLRSMTYSGQLRVEKRTPSAQREGGVHGLHSYEKQLF 606
            MAD + S  T YVP DG+  + L  S  G+TYNDF+ILPG+IDF   +V L S LT+KITLKTP ISSPMDTVTE+DMA  MAL+GGIG IHHNC+ EFQANEV KVK+FEQGFITDP+V+SPSHTV DV     + GFSG P+TE G +G KLVGIVT+RD+DF++ +DH    SE+MT + EL V   G+TLKEANEIL +SKKGKLPIV+D   LVA+I+RTDL+KNR+YPLASKDS+KQLL GAA+ T ++D  RL  L +AGVDV+VLDSSQGNS +QI  +  IK KYP+L+VI GNVVTAAQAKNLIDAG DGLRVGMG GSICITQEV A GRPQGTAV+ V+EYARRFGVP IADGGI   GH++KAL LGASTVMMGSLLA T EAPGEYF+ +GVRLK+YRGMGSL AM KS  SQ RYF E DKVK+AQGVSGS++DKGS+ KF+PYL AG+QHGC                    QDIGA+SL+ LRSM YSG+L+ EKRT SAQ EGGVHGLHSYEK+L+
Sbjct:    1 MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGC--------------------QDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 514
The following BLAST results are available for this feature:
BLAST of TCONS_00058725-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
IMDH10.000e+067.60Inosine-5'-monophosphate dehydrogenase 1 OS=Homo s... [more]
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