TCONS_00055242-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00055242-protein
Unique NameTCONS_00055242-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length804

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00055242-protein ID=TCONS_00055242-protein|Name=TCONS_00055242-protein|organism=Clytia hemisphaerica|type=polypeptide|length=804bp
RLILKAMRHWESETCIKFVKKTKQVDFLHIYPGNGCCSYVGRRGGRQYLS
LGRGCLRFGIVTHELGHAVGFWHEQNRPDRSIYIDVLYDNVDSSKFLNFD
PRGMNEVNTFDQIYDYESIMHYGTRFFSKNDGKTIRAKEVGKNVNENTIG
KSYYKFDGPVLSTQDILETNLLYKCTKITDCGGTLFAVKGSFTSTNFPSR
YPMDVKRDCIWIISTTQTKERNGKKTSLTLIFDQFHVGNEKNRKTGQCED
DYVEIREGKGFLSPYIVRYCGNTLPSPVTTTSGSLYVRLHTSGKNKNKKS
LSPQMFTGFQADFKTDICSHHIKQFPTRIQSPDFPFAYKKGQDCLWVIES
DKGMQIELDFPFFSLRELDKERGCLDYIEIHEGDGNSEKFIGRFCGTNSP
KKIISSLNQIKIHFHASKKKRLGWYLGFQANIKQKDIDECALGLHSCTQA
CINYPGGFFCGCYLGYHTVYQKDSRIAECVDKDECAIKNGGCSHACVNTA
GSFLCACPKGYTLAANKTTCIDINECQFKKQPCDHFCTNQIGSFKCSCKD
GYLLQNDNKTCNELPGCLASYKTPVGRISTPNIPVTYTHDVRCTWKIEVP
VHFKVALKLKVPWSNEGGDCRDSVTIHNDKYERKHRLNTQQICSQNDGVN
QIVMERNAAIIDFVVKYPFPKAIEINYHSVSSKEQHCGRTFNITHGRFRT
PGYPFRYPDSQSCVWTLHSPKRQRMKLRFVHFGLEAHKECQYDYVIVEEH
FYNMPAVKLIGRFCGNKNPPKMIIDGGRSYFKVKFHSDETMSGKGFKAIF
KEIG
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_034792XLOC_034792Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00055242TCONS_00055242Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001506Peptidase_M12A
IPR000859CUB_dom
IPR001881EGF-like_Ca-bd_dom
IPR000742EGF-like_dom
IPR006026Peptidase_Metallo
IPR024079MetalloPept_cat_dom
IPR018097EGF_Ca-bd_CS
IPR000152EGF-type_Asp/Asn_hydroxyl_site
IPR013032EGF-like_CS
IPR034035Astacin-like_dom
IPR009030Growth_fac_rcpt_
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0005509calcium ion binding
GO:0008237metallopeptidase activity
GO:0008270zinc ion binding
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0005509 calcium ion binding
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001506Peptidase M12APRINTSPR00480ASTACINcoord: 3..21
score: 41.32
coord: 55..73
score: 58.95
coord: 74..91
score: 39.07
coord: 113..128
score: 54.06
coord: 161..174
score: 41.07
IPR001506Peptidase M12APFAMPF01400Astacincoord: 2..176
e-value: 3.1E-53
score: 180.1
IPR000859CUB domainSMARTSM00042CUB_2coord: 318..431
e-value: 6.0E-20
score: 82.3
coord: 687..803
e-value: 7.9E-28
score: 108.4
coord: 181..316
e-value: 3.5E-21
score: 86.4
coord: 567..680
e-value: 6.3E-4
score: 26.7
IPR000859CUB domainGENE3D2.60.120.290coord: 314..433
e-value: 6.5E-25
score: 87.1
IPR000859CUB domainGENE3D2.60.120.290coord: 564..672
e-value: 1.3E-11
score: 44.3
IPR000859CUB domainGENE3D2.60.120.290coord: 677..803
e-value: 4.4E-31
score: 107.2
coord: 175..313
e-value: 2.9E-23
score: 82.0
IPR000859CUB domainPFAMPF00431CUBcoord: 318..424
e-value: 2.1E-22
score: 79.5
coord: 687..800
e-value: 1.0E-23
score: 83.6
coord: 181..298
e-value: 3.7E-16
score: 59.3
coord: 567..664
e-value: 6.2E-7
score: 29.6
IPR000859CUB domainPROSITEPS01180CUBcoord: 567..680
score: 11.598
IPR000859CUB domainPROSITEPS01180CUBcoord: 687..803
score: 26.896
IPR000859CUB domainPROSITEPS01180CUBcoord: 181..316
score: 22.87
IPR000859CUB domainPROSITEPS01180CUBcoord: 318..435
score: 20.201
IPR000859CUB domainCDDcd00041CUBcoord: 687..800
e-value: 2.37111E-27
score: 107.113
IPR000859CUB domainCDDcd00041CUBcoord: 318..415
e-value: 4.44747E-22
score: 92.0902
IPR000859CUB domainCDDcd00041CUBcoord: 181..313
e-value: 2.45127E-20
score: 87.0826
IPR000859CUB domainSUPERFAMILY49854Spermadhesin, CUB domaincoord: 687..802
IPR000859CUB domainSUPERFAMILY49854Spermadhesin, CUB domaincoord: 318..430
IPR000859CUB domainSUPERFAMILY49854Spermadhesin, CUB domaincoord: 567..664
IPR000859CUB domainSUPERFAMILY49854Spermadhesin, CUB domaincoord: 180..296
IPR001881EGF-like calcium-binding domainSMARTSM00179egfca_6coord: 481..521
e-value: 2.8E-10
score: 50.2
coord: 522..562
e-value: 2.2E-10
score: 50.5
coord: 436..480
e-value: 1.3E-7
score: 41.3
IPR001881EGF-like calcium-binding domainPFAMPF07645EGF_CAcoord: 436..467
e-value: 2.9E-6
score: 27.3
IPR000742EGF-like domainSMARTSM00181egf_5coord: 525..562
e-value: 1.1E-4
score: 31.6
coord: 484..521
e-value: 5.3E-6
score: 36.0
coord: 439..480
e-value: 8.9
score: 15.3
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 522..562
score: 9.604
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 481..521
score: 8.914
IPR006026Peptidase, metallopeptidaseSMARTSM00235col_5coord: 1..118
e-value: 3.1E-27
score: 106.5
NoneNo IPR availableGENE3D2.40.155.10coord: 463..481
e-value: 1.0E-6
score: 27.9
NoneNo IPR availableGENE3D2.10.25.10coord: 434..462
e-value: 4.7E-10
score: 39.0
coord: 523..562
e-value: 9.3E-14
score: 50.8
NoneNo IPR availableGENE3D2.10.25.10coord: 482..502
e-value: 2.7E-9
score: 36.5
NoneNo IPR availablePFAMPF14670FXa_inhibitioncoord: 526..561
e-value: 4.8E-9
score: 36.3
coord: 485..520
e-value: 2.6E-11
score: 43.5
NoneNo IPR availableGENE3D2.10.25.10coord: 503..522
e-value: 6.3E-15
score: 54.3
NoneNo IPR availableCDDcd00054EGF_CAcoord: 436..467
e-value: 5.92336E-4
score: 37.6162
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 2..175
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 1..174
e-value: 2.3E-47
score: 161.0
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 522..546
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 537..548
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 496..507
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 546..561
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 505..520
IPR034035Astacin-like metallopeptidase domainCDDcd04280ZnMc_astacin_likecoord: 2..173
e-value: 1.98941E-63
score: 210.505
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 436..567

Blast
[Close]
BLAST of TCONS_00055242-protein vs. Swiss-Prot (Human)
Match: TLL2 (Tolloid-like protein 2 OS=Homo sapiens GN=TLL2 PE=1 SV=1)

HSP 1 Score: 259.996 bits (663), Expect = 7.402e-74
Identity = 166/496 (33.47%), Postives = 242/496 (48.79%), Query Frame = 0 
Query:    1 RLILK-AMRHWESETCIKFVKKTKQVDFLHI-YPGNGCCSYVGRRGG-RQYLSLGRGCLRFGIVTHELGHAVGFWHEQNRPDRSIYIDVLYDNVDSSKFLNFDPRGMNEVNTFDQIYDYESIMHYGTRFFSKNDGKTIRAKEVGKNVNENTIGKSYYKFDGPVLSTQDILETNLLYKCTKITDCGGTLFAVKGSFTSTNFPSRYPMDVKRDCIWIISTTQTKERNGKKTSLTLIFDQFHVGNEKNRKTGQCEDDYVEIREGKGFLSPYIVRYCGNTLPSPVTTTSGSLYVRLHTSGKNKNKKSLSPQMFTGFQADFKTDICSHHIKQFPTRIQSPDFPFAYKKGQDCLWVIESDKGMQIELDFPFFSLRELDKERGCL-DYIEIHEGDGNSEKFIGRFCGTNSPKKIISSLNQIKIHFHASKKKRLGWYLGFQANIKQKDIDECALGLH-SCTQACINYPGGFFCGCYLGYHTVYQKDSRIAECVDKDECAIKNGG 491
            R I K AMRHWE  TC+ F+++T +  F+   Y   GCCSYVGRRGG  Q +S+G+ C +FGIV HELGH VGFWHE  RPDR  ++ ++ +N+   +  NF      EV++  + YD++SIMHY    FS+             N    TIG+         LS  DI +   LYKC     CG TL    G+F++  FP+ YP      C+W IS T  ++     TS+ L             K+  C  DYVE+R+G    +P + R+CG+ +P P+ +T   L+V   +S        L    F  ++A      C   + +   +IQSP++P  Y+  ++C+W I   +G  + L F  F   E+++   C  DY+E+ +G       IG FCG   P+ + SS N++ + F +          GF AN   K++DEC+   H  C   C+N  G + C C  GY              DK  C +  GG
Sbjct:  177 RAIFKQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVR------LSQGDIAQARKLYKCPA---CGETLQDTTGNFSAPGFPNGYPS--YSHCVWRISVTPGEKIVLNFTSMDLF------------KSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSS-----SNILGKGFFAAYEA-----TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAF---EIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKA---GFAANFF-KEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELA----------ADKKMCEVACGG 622

HSP 2 Score: 100.908 bits (250), Expect = 1.054e-21
Identity = 68/242 (28.10%), Postives = 118/242 (48.76%), Query Frame = 0 
Query:  177 KITDCGGTLFAVKGSFTSTNFPSRYPMDVKRDCIWIISTTQTKERNGKKTSLTLIFDQFHVGNEKNRKTGQCEDDYVEIREGKGFLSPYIVRYCGNTLPSPVTTTSGSLYVRLHTSGKNKNKKSLSPQMFTGFQADFKTDICSHHIKQFPTRIQSPDFPFA---YKKGQDCLWVIESDKGMQIELDFPFFSLRELDKERGC-LDYIEIHEGDGNSEKFIGRFCGTNSPKKIISSLNQIKIHF 414
            K   C   + +V+G+  S N+P +YP   +R+C W IS+T      G +  LT  F++F +   +     +C  D++E+ +G   L+P + R+CG+  P P   +  S+++R ++    + K         GFQA   T+       +  T+       F    Y     C WVI ++ G  +EL F  F   E+++E  C  DY+E ++G  +S   +GRFCG+   ++I S+ + + I F
Sbjct:  772 KEAGCAHKISSVEGTLASPNWPDKYPS--RRECTWNISSTA-----GHRVKLT--FNEFEIEQHQ-----ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRK---------GFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTF---EVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRF 987

HSP 3 Score: 84.3445 bits (207), Expect = 1.444e-16
Identity = 44/117 (37.61%), Postives = 67/117 (57.26%), Query Frame = 0 
Query:  684 EQHCGRTFNITHGRFRTPGYPFRYPDSQSCVWTLHSPKRQRMKLRFVHFGLEAHKECQYDYVIVEEHFYNMPAVKLIGRFCGNKNPPKMIIDGGRSYFKVKFHSDETMSGKGFKAIF 800
            E  CG      +G   +PG+P  YP +++CVW + +P + R+ L+F  F LE +  C+YD+V V       P  KL GRFCG++ P   +I    +  +V+F SD T+S +GF+A F
Sbjct:  617 EVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGL--SPDAKLHGRFCGSETPE--VITSQSNNMRVEFKSDNTVSKRGFRAHF 729

HSP 4 Score: 82.0333 bits (201), Expect = 7.796e-16
Identity = 39/119 (32.77%), Postives = 63/119 (52.94%), Query Frame = 0 
Query:  683 KEQHCGRTFNITHGRFRTPGYPFRYPDSQSCVWTLHSPKRQRMKLRFVHFGLEAHKECQYDYVIVEEHFYNMP--AVKLIGRFCGNKNPPKMIIDGGRSYFKVKFHSDETMSGKGFKAI 799
            KE  C    +   G   +P +P +YP  + C W + S    R+KL F  F +E H+EC YD++      Y+ P     ++GRFCG+K P   +  G   +  ++F+SD ++  KGF+A+
Sbjct:  772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHL----EMYDGPDSLAPILGRFCGSKKPDPTVASGSSMF--LRFYSDASVQRKGFQAV 884
The following BLAST results are available for this feature:
BLAST of TCONS_00055242-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TLL27.402e-7433.47Tolloid-like protein 2 OS=Homo sapiens GN=TLL2 PE=... [more]
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