TCONS_00054430-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00054430-protein
Unique Name	TCONS_00054430-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	695

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00054430-protein ID=TCONS_00054430-protein|Name=TCONS_00054430-protein|organism=Clytia hemisphaerica|type=polypeptide|length=695bp
MSSSNTLNSDNFAKQQLRKISTSLKGAKRFGSESDLLDDSGSNKFFSVQY
SETGNGGEAKTTKIPAKKGKSLKESLENVFQTYDFTFDSHAVFLETSKTP
LPLASDCFPYGGCTLNIRATEDVEVDKRIMTLMRDGDKKSPDQSKRFSNL
LLHYSLNGFEEDEVDGGAPTDEEIFNRDFYLESSWKDVVDGNEEMERHDR
VQQEAIWELITTEKTYIADLRVVTEVFKKCFSRLKDDGFLTDVDPFLIFA
NIDEIHDLNVEFWKLLITVVENSRKSRQPIKPSDLINAFDRFEVLFQPYI
TFCNHDTSNINLPNYTDAVNEQVKEYFMWCDDHPRCKRIKLQGFLIKPLQ
RVTKYSLLIRAVEGKTQNEDEKEMLGKMRNRVETFVSKINSAVHMRQEHE
KMLAVLARLETYAPVEAVNEEAEKIMNEYSSLDLKGNIPDFPLERKRLIV
KEGPMRLVEKQVKKEVQGYLFSDVFVLARPKKNTDKYKVIRQPFRLDKTV
IRVLKDAGSFLVIYLNEYNVMSNAFVLQINPKDQAEWLTAFDKAKTDYET
TVLEYRLKRLEEEEEDYISNGDKGRKMTRGKAMRNRFSARNSTIRATILN
GDTLMPPPTPISPKAEMRARVMSASTPKQLKQTLKGRRPLTPNARRKTSY
WKNPSKQSPINSPTKSVFKITINNKDIRKIGTRLEIEQRERSKSF

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_034302	XLOC_034302	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00054430	TCONS_00054430	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001849	PH_domain
IPR000219	DH-domain
IPR011993	PH_dom-like
IPR029071	Ubiquitin-rel_dom

Vocabulary: **Biological Process**
Term	Definition
GO:0035023	regulation of Rho protein signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005089	Rho guanyl-nucleotide exchange factor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035023	regulation of Rho protein signal transduction
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 415..435
None	No IPR available	GENE3D	3.10.20.90		coord: 58..117 e-value: 5.0E-6 score: 26.0
None	No IPR available	GENE3D	1.20.900.10		coord: 181..411 e-value: 1.2E-44 score: 151.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 623..663
None	No IPR available	CDD	cd00160	RhoGEF	coord: 202..390 e-value: 3.96928E-34 score: 127.799
IPR001849	Pleckstrin homology domain	SMART	SM00233	PH_update	coord: 449..548 e-value: 0.0078 score: 25.4
IPR000219	Dbl homology (DH) domain	SMART	SM00325	RhoGEF_3	coord: 205..391 e-value: 3.5E-41 score: 152.8
IPR000219	Dbl homology (DH) domain	PFAM	PF00621	RhoGEF	coord: 206..390 e-value: 1.9E-33 score: 116.1
IPR000219	Dbl homology (DH) domain	PROSITE	PS50010	DH_2	coord: 201..392 score: 25.637
IPR000219	Dbl homology (DH) domain	SUPERFAMILY	48065	DBL homology domain (DH-domain)	coord: 192..411
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 419..551 e-value: 4.4E-13 score: 49.0
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 416..546
IPR029071	Ubiquitin-related domain	SUPERFAMILY	54236	Ubiquitin-like	coord: 60..128

Blast

[Close]

BLAST of TCONS_00054430-protein vs. Swiss-Prot (Human)
Match: PKHG5 (Pleckstrin homology domain-containing family G member 5 OS=Homo sapiens GN=PLEKHG5 PE=1 SV=3)

HSP 1 Score: 259.996 bits (663), Expect = 1.510e-74
Identity = 130/357 (36.41%), Postives = 213/357 (59.66%), Query Frame = 0

Query:  176 NRDFYLESSWKDVVDGNEEMERHDRVQQEAIWELITTEKTYIADLRVVTEVFKKCFSRLKDDGFLTDVDPFLIFANIDEIHDLNVEFW-KLLITVVENSRKSRQPIKPSDLINAFDRFEVLFQPYITFCNHDTSNINLPNYTDAVNEQVKEYFMWCDDHPRCKRIKLQGFLIKPLQRVTKYSLLIRAVEGKTQNEDEKEMLGKMRNRVETFVSKINSAVHMRQEHEKMLAVLARLETYAPVEAVNEEAEKIMNEYSSLDLKGNIPDFPLERKRLIVKEGPMRLVE-KQVKKEVQGYLFSDVFVLARPKKNTDKYKVIRQPFRLDKTVIRVLKDAGSFLVIYLNEYNVMSNAFVLQIN 530
            N    LE SW++++DG+E++ R    QQEA+WEL+ TE +YI  LRV+  +F  C   L++ G L +V+   +F+NI EI  L+   W  ++  V+E +R++R  ++P D +  F  F  LF+PYI +C  +   +         N+  + Y  W + HP+C+R+KL   L KP QR+TKY LL+++V  KT+    KE +  M   VE F+  +N+ +  RQE +++ AV++R++ Y  VE+ ++E +K++ E+  LDL   IP    E  R ++ EG +R+ E K  K +V  +LF+D+ ++ +  K  ++ +VIR P  +DK V R L+D GSFL+IYLNE++    A+  Q +
Sbjct:  367 NACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQAS 723

The following BLAST results are available for this feature:

BLAST of TCONS_00054430-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00054430-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
PKHG5	1.510e-74	36.41	Pleckstrin homology domain-containing family G mem...	[more]

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TCONS_00054430-protein (polypeptide) - C. hemisphaerica