TCONS_00053826-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00053826-protein
Unique NameTCONS_00053826-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1233

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00053826-protein ID=TCONS_00053826-protein|Name=TCONS_00053826-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1233bp
MNGDANGKPLKQTSSLVKGRMQVSLLDDTVVAFDVEQRSKGHELYAKVNK
HLNLDEPEFFGLLFQDEHENQTWLDHMKPISKQVKDPTKITFKFRVRFYT
PDPNSLQEYTRYLFTLQVRRDLLDGRLYCVEDTGALLASYIVQGELGDYD
PLNHKEGYLAGFQFVPNQTKDIEEKIVSYHRSHRGESPAESDHNMLEIAR
KIEMYGITLYPAQDSDGVKLNLAVYHSGILVFQDRNRVINNFSWANIRKV
TFKKKRFLIKLHKGTNEENDTLLFNLCSRAGAKSFWKVCINHHVFFRYNK
APRLKKKSSFKRGSRYRYSGRTKKEISEEASNKFQASSVDPGSDRGHARL
SGTYNFPETPSSHAVSSSASFNRQVSEDQGSYSIGGEAYSPEPIRHEITT
PLPTYQSTIEPSPPTQHTVITMQHQETLDTDSCHGEAGLVPPSYEDVVNT
TTIENDAGDSDKYSVHEVEQETEMESTPPITSSIDYQVETDLPEADLPQA
SSSEPPTPPSTNGFSLTNGHAEGDDLSLDATINITSTDEGGLGDEMESMF
NKLTSEYGSKNTSWKYDLSPLSSPSANRNTSFDHEDSKIEADKHHSTLAP
EADADSEVQLREQVKALYLQNCPTTHSYDSDSDASAISVDDEGSAFEDDL
SYASSATSSVSSIHKNRDYLSELRLKYRSNGKIYHIAKEILQTERTYVKD
LEVLTVSFRDVVENDNVLPARLLKFLYENIDPLYDFHCSLLAELEERISL
WDSSSTTEASRDNIQKIGDIMHRNMRQIKMYTSCIKKHCDIIIELEKYAN
KSPDFEKAYKEFEMSKVCYLSVNSFLMKPTQRILYYRSMLNKLTNEYGKG
SADAIDSKVAYEEIVEACKIIEPSISKLENMHKLVELERDLVAITDLLHP
KRLFIREGCLHKICRKGPQPRMFFLLSDILLYTSQGVTATNQFRARAQIP
LRSIRVEEGGVELHGLYAFTIVGPGTKSFIVAASSPDEKQKWMEDIRRAI
NNAIKMGMCVNCQSNKSEFILYVGQDNSHMCHKCQSEIEQLGNMAPEERL
QFWQSRFPPPPNIKRPSLDADSDDEGSYTVNDMYNSLDRRHAHSRTISTR
RVCWHRNTSISMKEYTLSIQNSISGELFRRYKNTSKWQKLWVVFTNFCLY
FFKTGDEDAPLANLPLLGYTISRPTEAETHEEFAFKLQFKTHQYLFKTDN
EYTYERWYEVLSTATKASNTLSSRSRRKLPSIS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033965XLOC_033965Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00053826TCONS_00053826Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR019749Band_41_domain
IPR000798Ez/rad/moesin-like
IPR001849PH_domain
IPR018980FERM_PH-like_C
IPR000219DH-domain
IPR014352FERM/acyl-CoA-bd_prot_3-hlx
IPR011993PH_dom-like
IPR019748FERM_central
IPR018979FERM_N
IPR019747FERM_CS
IPR000299FERM_domain
IPR029071Ubiquitin-rel_dom
Vocabulary: Molecular Function
TermDefinition
GO:0008092cytoskeletal protein binding
GO:0005089Rho guanyl-nucleotide exchange factor activity
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
Vocabulary: Cellular Component
TermDefinition
GO:0005856cytoskeleton
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
cellular_component GO:0005856 cytoskeleton
molecular_function GO:0008092 cytoskeletal protein binding
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019749Band 4.1 domainPRINTSPR00935BAND41coord: 190..206
score: 37.62
coord: 116..129
score: 50.74
coord: 52..64
score: 42.95
coord: 129..149
score: 50.69
IPR019749Band 4.1 domainSMARTSM00295B41_5coord: 15..210
e-value: 1.3E-61
score: 220.7
IPR000798Ezrin/radixin/moesin-likePRINTSPR00661ERMFAMILYcoord: 83..102
score: 38.06
coord: 125..146
score: 43.94
coord: 32..51
score: 24.72
coord: 213..233
score: 24.07
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 904..1003
e-value: 4.8E-17
score: 72.6
coord: 1121..1218
e-value: 4.6E-14
score: 62.7
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 905..1000
e-value: 1.5E-8
score: 35.0
coord: 1123..1214
e-value: 5.1E-12
score: 46.1
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 1120..1216
score: 12.825
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 903..1001
score: 13.029
IPR018980FERM, C-terminal PH-like domainSMARTSM01196FERM_C_3coord: 214..304
e-value: 8.9E-28
score: 108.3
IPR018980FERM, C-terminal PH-like domainPFAMPF09380FERM_Ccoord: 214..302
e-value: 1.7E-20
score: 73.1
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 686..873
e-value: 3.1E-29
score: 113.1
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 686..869
e-value: 3.5E-27
score: 95.7
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 682..881
score: 23.436
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 681..892
IPR014352FERM/acyl-CoA-binding protein, 3-helical bundleGENE3D1.20.80.10coord: 98..202
e-value: 2.4E-27
score: 95.0
IPR011993PH domain-likeGENE3D2.30.29.30coord: 205..301
e-value: 3.6E-23
score: 81.3
IPR011993PH domain-likeGENE3D2.30.29.30coord: 888..1113
e-value: 1.7E-30
score: 104.8
IPR011993PH domain-likeGENE3D2.30.29.30coord: 1114..1230
e-value: 4.7E-18
score: 64.3
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 1055..1215
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 879..1000
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 203..332
NoneNo IPR availableGENE3D1.20.900.10coord: 677..887
e-value: 1.4E-38
score: 132.1
NoneNo IPR availableGENE3D3.10.20.90coord: 19..97
e-value: 4.7E-23
score: 80.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 453..481
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 496..524
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 321..381
NoneNo IPR availableCDDcd00160RhoGEFcoord: 684..872
e-value: 2.95108E-29
score: 115.858
NoneNo IPR availableCDDcd01220PH1_FARP1-likecoord: 897..1003
e-value: 2.7017E-46
score: 162.099
IPR019748FERM central domainPFAMPF00373FERM_Mcoord: 102..210
e-value: 2.0E-15
score: 57.1
IPR019748FERM central domainCDDcd14473FERM_B-lobecoord: 110..201
e-value: 2.45313E-26
score: 104.636
IPR019748FERM central domainSUPERFAMILY47031Second domain of FERMcoord: 105..205
IPR018979FERM, N-terminalPFAMPF09379FERM_Ncoord: 23..85
e-value: 2.3E-14
score: 53.0
IPR019747FERM conserved sitePROSITEPS00660FERM_1coord: 73..102
IPR000299FERM domainPROSITEPS50057FERM_3coord: 19..300
score: 83.248
IPR029071Ubiquitin-related domainSUPERFAMILY54236Ubiquitin-likecoord: 22..101

Blast
[Close]
BLAST of TCONS_00053826-protein vs. Swiss-Prot (Human)
Match: FARP2 (FERM, RhoGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens GN=FARP2 PE=1 SV=3)

HSP 1 Score: 439.499 bits (1129), Expect = 3.492e-135
Identity = 236/537 (43.95%), Postives = 337/537 (62.76%), Query Frame = 0 
Query:  684 YHIAKEILQTERTYVKDLEVLTVSFRDVVENDNVLPARLLKFLYENIDPLYDFHCSLLAELEERISLWDSSSTTEASRDNIQKIGDIMHRNMRQIKMYTSCIKKHCDIIIELEKYANKSPDFEKAYKEFEMSKVCYLSVNSFLMKPTQRILYYRSMLNKLTNEYGKGSADAIDSKVAYEEIVEACKIIEPSISKLENMHKLVELERDLVAITDLLHPKRLFIREGCLHKICRKGPQPRMFFLLSDILLYTSQGVTATNQFRARAQIPLRSIRVEEGGVELHGLYAFTIVGPGTKSFIVAASSPDEKQKWMEDIRRAINNAIKMGMCVNCQSNKSEFILYVGQDNSHMCHKCQSEIEQLGNMAPEERLQFWQSRFPPPPNIKRPSLDADSDDEGSYTVNDMYNSLDRRHAHSRTISTRRVCWHRNTSISMKEYTLSIQNSISGELFRRYKNTSKWQKLWVVFTNFCLYFFKTGDEDAPLANLPLLGYTISRPTEAE-THEEFAFKLQFKTHQYLFKTDNEYTYERWYEVLSTATKASN 1219
            Y I KEIL TERTY+KDLEV+TV FR  V  ++ +PA L+  L+ NIDP+Y+FH   L E+E+R++LW+  S    ++ + Q+IGDI+ RNMRQ+K +TS  ++H +++ ELEK   +    E  YKEFE+ KVCYL +N+FL+KP QR+L+YR +L +L   Y  G  D  D   A + I E    ++  + +LEN+ KL EL+RDLV I +L+ P R FIREGCLHK+ +KG Q RMFFL SD+LLYTS+GV  T+ FR R  +PL+ + VEE   E    + FTI     K+ +VAAS+  EK+KWM D+  AI  A K G                                  G+ AP    +   +R P  PN    SL+ +S+D+       + +SL+  H   R  +T  VCW+RNTS+S  +++ +++N +SG L R++KN+  WQKLWVVFTNFCL+F+KT  +D PLA+LPLLGY++S P EA+  H+++ FKLQFK+H Y F+ +++YT+ERW EV+  A+ ++ 
Sbjct:  537 YFIVKEILATERTYLKDLEVITVWFRSAVVKEDAMPATLMTLLFSNIDPIYEFHRGFLREVEQRLALWEGPSKAH-TKGSHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKRCKKLEAVYKEFELQKVCYLPLNTFLLKPIQRLLHYRLLLRRLCGHYSPGHHDYADCHDALKAITEVTTTLQHILIRLENLQKLTELQRDLVGIENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKGVAGTSHFRIRGLLPLQGMLVEESDNEWSVPHCFTIYA-AQKTIVVAASTRLEKEKWMLDLNSAIQAA-KSG----------------------------------GDTAPALPGRTVCTRPPRSPN--EVSLEQESEDDA----RGVRSSLE-GHGQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSIPREADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVIQGASSSAG 1029

HSP 2 Score: 296.975 bits (759), Expect = 5.624e-84
Identity = 147/309 (47.57%), Postives = 209/309 (67.64%), Query Frame = 0 
Query:   21 MQVSLLDDTVVAFDVEQRSKGHELYAKVNKHLNLDEPEFFGLLFQDEHENQTWLDHMKPISKQVKDPTKITFKFRVRFYTPDPNSLQ-EYTRYLFTLQVRRDLLDGRLYCVEDTGALLASYIVQGELGDYDPLNHKEGYLAGFQFVPNQTKDIEEKIVSYHRSHRGESPAESDHNMLEIARKIEMYGITLYPAQDSDGVKLNLAVYHSGILVFQDRNRVINNFSWANIRKVTFKKKRFLIKLHKGTNEE-NDTLLFNLCSRAGAKSFWKVCINHHVFFRYNKAPRLKKKSS-FKRGSRYRYSGRTKKEI 326
            ++V LLD+T+  FD+E +  G  L  +V K LNL E ++FG+ FQ+      WL+ MKPI +Q++ P  +  +  V+F+ PDP  LQ EYTRYLF LQ++RDLL+ RL C + T ALL S+++Q E+GDYD    +E +L   +++P Q   + EKI+ +H+ H G++PAESD  +LEIARK+EMYGI  + A D +G K+ LAV H G+LVFQ   + IN F+W+ +RK++FK+KRFLIKLH   +    DTL F L SR   K+FWK+C+ +H FFR    P+ K K+  F RGS +RYSGRT+K++
Sbjct:   46 LRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPIIRQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDYDETLDRE-HLKVNEYLPGQQHCL-EKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTK-INTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLLDQPKPKAKAVFFSRGSSFRYSGRTQKQL 351
The following BLAST results are available for this feature:
BLAST of TCONS_00053826-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FARP23.492e-13543.95FERM, RhoGEF and pleckstrin domain-containing prot... [more]
back to top