TCONS_00052156-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00052156-protein
Unique NameTCONS_00052156-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length907

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00052156-protein ID=TCONS_00052156-protein|Name=TCONS_00052156-protein|organism=Clytia hemisphaerica|type=polypeptide|length=907bp
MYSFPSLGQNVVYIVTIGIGKKEYVYSMSLNDTFKIGPTDTCVYGQRNPD
SFQVTVYPVGSEGFNRNGSLSQKLVPAFKIPSITNISWGLPQYVKTSGGY
ERIEYLVQVIGDPDIKLHSVTYDINRECAGIRDYLTNGDLTRGLFNPPLI
NIPVKFKIEYAGDQSRVDPYKELTKCHYVFSAHGEYMCYGVPTYSAKFNY
GGCQTVQNFPREECPSTQPSLKEIETYRDYNLSELICTEYVNQSCYSNVP
DEDNEQCLQCVNGTYNLTVKWFENNRPSHYDKYVLTYGRVLTFETVNNKP
KFTNEMTEHYLPLVATHGNSTTTFTLYNITPGIEYGVRIRIHDSYLQLDA
GSSPIKVINIPKIANVTREMIFSTTASTIPYIIAPDSSRTIVIGILIPLA
VLVLMLTMYLFYKRYVQTKDLRNDPLKYVYNYKGDVKTDEWEIFPKTITL
DEKIGEGAFGTVFSAYLDGATFSQSNYSKRIGGASLLELGTNPKVAVKLL
KEGANELERANFREEISLMKDIGYHKNIVNLIGCSTIHPPLCLLVEYMVH
GDMLHYLRKRRSRLLSTELITGESGPAQNFMYTKNFSVVLQSNATSAENS
EGTNSHSIYSMGSEDSGFYDPENIITPDDLLCFAWQIASGMEFLSLNKMV
HRDLAARNILVGANKLVKISDFGLTRHVGSEMVYMSSKNQKLPIKWMSVE
AIFDQIFTTYSDVWAYGVVLFEITTLGGTPYPTVSNRELLNLLASGYRME
KPQNCTDLMYDVMMHCWNEDPLQRPTFTELRDHLEEIMSQGCHYMSFDID
EKNAYYNVASHKSIPDENEDDVEIEEAILQKAPQFLTIEELKKERNDRMN
VGDDIKLAEIEQSFEEVWNAFDEKNSIKKLDSSVVSETENRYTKTSDILP
NASLGIK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033025XLOC_033025Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00052156TCONS_00052156Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR020635Tyr_kinase_cat_dom
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR013783Ig-like_fold
IPR008266Tyr_kinase_AS
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004713protein tyrosine kinase activity
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 448..784
e-value: 1.5E-131
score: 453.0
NoneNo IPR availableGENE3D1.10.510.10coord: 553..889
e-value: 1.7E-42
score: 144.9
NoneNo IPR availableGENE3D3.30.200.20coord: 428..552
e-value: 2.8E-21
score: 75.1
NoneNo IPR availableCDDcd00192PTKccoord: 452..785
e-value: 1.86845E-120
score: 368.02
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 448..784
e-value: 1.6E-89
score: 299.5
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 254..364
e-value: 4.8E-4
score: 19.8
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 649..661
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 448..788
score: 36.033
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 430..571
coord: 611..784

Blast
BLAST of TCONS_00052156-protein vs. Swiss-Prot (Human)
Match: FGFR1 (Fibroblast growth factor receptor 1 OS=Homo sapiens GN=FGFR1 PE=1 SV=3)

HSP 1 Score: 238.039 bits (606), Expect = 2.376e-66
Identity = 131/350 (37.43%), Postives = 191/350 (54.57%), Query Frame = 0
Query:  440 EWEIFPKTITLDEKIGEGAFGTVFSAYLDGATFSQSNYSKRIGGASLLELGTNPKVAVKLLKEGANELERANFREEISLMKDIGYHKNIVNLIGCSTIHPPLCLLVEYMVHGDMLHYLRKRRSRLLSTELITGESGPAQNFMYTKNFSVVLQSNATSAENSEGTNSHSIYSMGSEDSGFYDPENIITPDDLLCFAWQIASGMEFLSLNKMVHRDLAARNILVGANKLVKISDFGLTRHVGSEMVYMSSKNQKLPIKWMSVEAIFDQIFTTYSDVWAYGVVLFEITTLGGTPYPTVSNRELLNLLASGYRMEKPQNCTDLMYDVMMHCWNEDPLQRPTFTELRDHLEEIMS 789
             WE+    + L + +GEG FG V  A   G    + N   R+            KVAVK+LK  A E + ++   E+ +MK IG HKNI+NL+G  T   PL ++VEY   G++  YL+ RR              P   + Y  +                                 ++PE  ++  DL+  A+Q+A GME+L+  K +HRDLAARN+LV  + ++KI+DFGL R +     Y  + N +LP+KWM+ EA+FD+I+T  SDVW++GV+L+EI TLGG+PYP V   EL  LL  G+RM+KP NCT+ +Y +M  CW+  P QRPTF +L + L+ I++
Sbjct:  470 RWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPN---RVT-----------KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP-------------PGLEYCYNPS---------------------------------HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 759          
The following BLAST results are available for this feature:
BLAST of TCONS_00052156-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FGFR12.376e-6637.43Fibroblast growth factor receptor 1 OS=Homo sapien... [more]
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