TCONS_00052076-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00052076-protein
Unique Name	TCONS_00052076-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	483

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00052076-protein ID=TCONS_00052076-protein|Name=TCONS_00052076-protein|organism=Clytia hemisphaerica|type=polypeptide|length=483bp
MAPNWWFHYLNTFTFIYVTFELANCDVGHGKAKDGKDVIMEKEIHEYIFD
GMNKDIRPEIKHGVPTHVHFDMKLQKIVNLDVKHQQFVVNTFIKMRWVDP
QLRWNKTKYEGIESINVGSSLIWTPDIVLYNAANEDSFAHTDVYKTKALV
SHTGEVXANEDSFAHTDVYKTKALVSHTGEVLWSAPVMWRVSCEFDITWF
PLDRQECTMKFGSWSYMNNQMRLSLWYDVSQSVNEIGHSHFMVKSGEWDI
NDVEINQEEVPYPCCQQPFSTIQYTITLNRMVLYYFLYIIMPLVSQILVF
FCIFHIPYGVGDRMSFGVTILLGITVYLLVISEKLPEKSDNKPMLGLCFI
AEFYILSISLIFACLNIKLASKTTPPPVFLLHLCSLKDVCHSGGNGVSSE
NLLQMAPMHGSSGYLHGDGESQSPEAPIVQKKRYAPSPEQCKEQWEKISL
YLDRVFFYVFCGTALLIPLIVAASLDRKMLGVV

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_032983	XLOC_032983	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00052076	TCONS_00052076	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 121..132 score: 51.21 coord: 193..207 score: 46.58 coord: 276..288 score: 28.19 coord: 88..104 score: 29.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 37..285 e-value: 3.9E-60 score: 202.5
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 42..158 e-value: 1.6E-28 score: 99.6 coord: 160..281 e-value: 4.2E-28 score: 98.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 161..280
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 41..159
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 290..373 e-value: 9.8E-10 score: 38.8
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 283..466
None	No IPR available	GENE3D	1.20.58.390		coord: 286..479 e-value: 1.0E-19 score: 70.1
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 193..207

Blast

[Close]

BLAST of TCONS_00052076-protein vs. Swiss-Prot (Human)
Match: ACHA3 (Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapiens GN=CHRNA3 PE=1 SV=4)

HSP 1 Score: 189.119 bits (479), Expect = 4.142e-54
Identity = 109/336 (32.44%), Postives = 180/336 (53.57%), Query Frame = 0

Query:   41 EKEIHEYIFDGMNKDIRPEIKHGVPTHVHFDMKLQKIVNLDVKHQQFVVNTFIKMRWVDPQLRWNKTKYEGIESINVGSSLIWTPDIVLYNAANEDSFAHTDVYKTKALVSHTGEVXANEDSFAHTDVYKTKALVSHTGEVLWSAPVMWRVSCEFDITWFPLDRQECTMKFGSWSYMNNQMRLSLWYDVSQSVNEIGHSHFMVKSGEWDINDVEINQEEVPYPCCQQPFSTIQYTITLNRMVLYYFLYIIMPLVSQILVFFCIFHIPYGVGDRMSFGVTILLGITVYLLVISEKLPEKSDNKPMLG--LCFIAEFYILSISLIFACLNIKLASKTT 374
            E  + E +F+  N+ IRP      P  +HF++ + ++V +D  +Q    N ++K  W D +L+WN + Y G E + V +  IW PDIVLYN A                    G+   ++         KTKAL+ +TGEV W  P +++ SC+ D+T+FP D Q CTMKFGSWSY   ++ L L   +  S+N   +     +SGEW I      + ++ Y CC++ +  I Y++ + R+ L+Y + +I+P +    +   +F++P   G++++  +++LL +TV+LLVI+E +P  S   P++G  L F   F  LSI +    LN+   + TT
Sbjct:   35 EHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNA-------------------VGDFQVDD---------KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL---IGSSMNLKDYW----ESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTT 335

The following BLAST results are available for this feature:

BLAST of TCONS_00052076-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00052076-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA3	4.142e-54	32.44	Neuronal acetylcholine receptor subunit alpha-3 OS...	[more]

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TCONS_00052076-protein (polypeptide) - C. hemisphaerica