TCONS_00051903-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00051903-protein
Unique NameTCONS_00051903-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length781

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00051903-protein ID=TCONS_00051903-protein|Name=TCONS_00051903-protein|organism=Clytia hemisphaerica|type=polypeptide|length=781bp
MRLIFAVLVVIQLFQNVVSFDIWKTIEESNKDFYKKQKGLSDDNGHRLVG
GDIFMTTQDFLKNRKVLSAPPQNAPKQKIPPVFDFHRKYWKRRIPYQIGY
EFNTKERQVIQDSMKYIEARSCLKFSNSKTSSDKHWIRFYKGAGCHSGIG
RSYYYDSKSTDVSLGNGCVVISIIVHELLHSLGFFHEQSRTDRDSYLQIY
LSKVDKGWHSNFDKNEVGMEAYHGTPYDLRSIMQYGKSTFRKASASGNVM
ESKGDPDAPIGNSDMSDWDITELNRRYQCQHVDENGKKHVAIMSGWSQWV
GWTRCMENWRKECSKARYRFCVDSDNCPGGNKWGTDEIVELCTAAECRAD
KEAVDGVWGRWSEFTSCNGKCGWGIQQRTRRCNNPPPRGKGKRCFGNSME
RKLCRKQRCSAGPDKLDQNFDYGFGAWTAKEFSRKNGRASYQLPKDGPSK
DHTSQVSGKAGYYAAAISEKGWYRDGKGKQIMAELSATTTRTHAKACLSF
YYMLNGADIADKNAISVYWKTSTGVYQNSPFMKAGNMGKTWFYAAVDMKN
VAAGTKVYIEVRFGKWRGSVVAVDDIAFDNNECPKFLDSTKCVDDPSFDC
KSKKNMCAFDWRAMIPRCCQTCSDPSLKITGETCLDNPTYAGKCKEWTEK
GECAKNKNWMAKQCCVSCKSAPKTTPKPTLPPVTTTTKTPETNTCVDIEG
DMAPGEVTSTKCEQWANKGYCEKYKKFMLDHCCRSCENYYKEPACTDNAS
YKDKCDGWASKEISECAVNSWMPKNCCVSCK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_032853XLOC_032853Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00051903TCONS_00051903Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001506Peptidase_M12A
IPR000998MAM_dom
IPR006026Peptidase_Metallo
IPR000884TSP1_rpt
IPR024079MetalloPept_cat_dom
IPR034035Astacin-like_dom
IPR013320ConA-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
GO:0008270zinc ion binding
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0016020 membrane
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001506Peptidase M12APRINTSPR00480ASTACINcoord: 110..128
score: 22.11
coord: 265..278
score: 34.64
coord: 168..186
score: 51.58
coord: 187..204
score: 41.02
coord: 226..241
score: 46.88
IPR001506Peptidase M12APFAMPF01400Astacincoord: 89..280
e-value: 3.8E-49
score: 166.8
IPR000998MAM domainSMARTSM00137MAM_2coord: 413..585
e-value: 2.7E-4
score: -1.0
IPR000998MAM domainPFAMPF00629MAMcoord: 419..584
e-value: 7.4E-17
score: 61.6
IPR000998MAM domainPROSITEPS50060MAM_2coord: 416..585
score: 18.776
IPR006026Peptidase, metallopeptidaseSMARTSM00235col_5coord: 86..231
e-value: 2.0E-30
score: 117.1
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 358..410
e-value: 7.1E-8
score: 42.2
coord: 296..348
e-value: 2.0
score: 6.6
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 360..409
e-value: 6.2E-7
score: 29.4
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 354..409
e-value: 1.1E-12
score: 47.6
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 355..410
score: 11.823
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 354..404
NoneNo IPR availableGENE3D2.60.120.200coord: 417..585
e-value: 3.0E-19
score: 69.1
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 88..280
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 76..279
e-value: 2.6E-42
score: 144.5
IPR034035Astacin-like metallopeptidase domainCDDcd04280ZnMc_astacin_likecoord: 91..277
e-value: 5.39717E-55
score: 186.238
IPR013320Concanavalin A-like lectin/glucanase domainSUPERFAMILY49899Concanavalin A-like lectins/glucanasescoord: 416..583

Blast
BLAST of TCONS_00051903-protein vs. Swiss-Prot (Human)
Match: MEP1A (Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE=1 SV=2)

HSP 1 Score: 114.775 bits (286), Expect = 2.923e-26
Identity = 82/278 (29.50%), Postives = 127/278 (45.68%), Query Frame = 0
Query:    7 VLVVIQLFQNVVSFDIWKTIEESNKDF-YKKQKGLSDDN---GHRLVGGDIFMTTQDFLKNRKVLSAPPQNAPKQKIPPVFDFHRKYWKRRIPYQIGYEFNTKERQVIQDSMKYIEARSCLKFSNSKTSSDKHWIRFYKGAGCHSGIGRSYYYDSKSTDVSLGNGCVVISIIVHELLHSLGFFHEQSRTDRDSYLQIYLSKVDKGWHSNFDKNEVGMEAYHGTPYDLRSIMQYGKSTFRKASASGNVMESKGDPDAPIGNS-DMSDWDITELNRRYQC 279
            +L    LF ++ +  I    EE+  D  + +QK +S+ N   G  L  GDI +      K+R  L  P                   W   IPY +        +  I  + +    +SC+ F   +  S   +I F +  GC S +G  +       ++S+G GC   +II HE+LH+LGF+HEQSRTDRD Y+ I+  ++  G+  NFD  +  +     TPYD  S+M Y   +F K ++   +     + ++ IG   D S  D+  LNR Y C
Sbjct:    9 ILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQ-----KSRNGLRDP----------------NTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESS--YIIFQQFDGCWSEVGDQHV----GQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNC 259          
The following BLAST results are available for this feature:
BLAST of TCONS_00051903-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MEP1A2.923e-2629.50Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE... [more]
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