TCONS_00049526-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049526-protein
Unique NameTCONS_00049526-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length620

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049526-protein ID=TCONS_00049526-protein|Name=TCONS_00049526-protein|organism=Clytia hemisphaerica|type=polypeptide|length=620bp
AVVVCWTWLLLIFLYSMDESTLLKNLAFQFGIEAFHQPQVNVLRAFFNGK
HTYFSAPTGYGKSVVFQAVPRYFEELRPEISNPVLLVFSPLIALINDQIK
AAGDSCIMAISLDKTVTDECYEDIKAGTYSLVYACPEVLETKRWRMLFSD
SEFVDRCIGVVVDEAHVMVEWGKSSNESTKAFRESYSKIVELQSLLSSKA
RFMLFTATATSATQATIFSMLNLQSNDVYCEIYHPNKNNVRFTVEQISMG
KEDGRYLVNFFDFIMEEIIAKKEHTCKTIIYVNTRKEVNLLNNGMASKLG
VDLFLSGKEGNPRYRLVEEFHAYSPQSVKNHVLAQASILESHLRVIICTS
AFGMGVNVKGFNRCIHFGPPSTVESFVQEVGRVGRDGSPSESILMFHKSL
ATHASSDMVEYAGSHVKCRRDFLMVKFPGTYSSLSNCTCCDLCSNVCQCK
EPNCCKKLKQLNVNAQAPVTERRRNVSMAERDELRGLLNDFRMEIFNKKK
NLKQVSLPNLFHEFTEYHVKQVMVNVTKIFNIQDLKSRVEIWRTRHAIEV
LKIINSVFHDIEIDQMEQLNLEEEPLGLDDASFMNDTRYQSVTDSQVNSY
LLSDCTDGNISKRTLEDEDF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031419XLOC_031419Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049526TCONS_00049526Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR014001Helicase_ATP-bd
IPR001650Helicase_C
IPR011545DEAD/DEAH_box_helicase_dom
IPR011991WHTH_DNA-bd_dom
IPR027417P-loop_NTPase
Vocabulary: Molecular Function
TermDefinition
GO:0003676nucleic acid binding
GO:0005524ATP binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005524 ATP binding
molecular_function GO:0003676 nucleic acid binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR014001Helicase superfamily 1/2, ATP-binding domainSMARTSM00487ultradead3coord: 31..247
e-value: 7.5E-11
score: 52.0
IPR014001Helicase superfamily 1/2, ATP-binding domainPROSITEPS51192HELICASE_ATP_BIND_1coord: 43..227
score: 15.42
IPR001650Helicase, C-terminalSMARTSM00490helicmild6coord: 293..387
e-value: 4.6E-9
score: 46.1
IPR001650Helicase, C-terminalPFAMPF00271Helicase_Ccoord: 264..386
e-value: 8.2E-14
score: 51.8
IPR001650Helicase, C-terminalPROSITEPS51194HELICASE_CTERcoord: 256..435
score: 14.234
IPR011545DEAD/DEAH box helicase domainPFAMPF00270DEADcoord: 39..212
e-value: 1.5E-10
score: 41.0
NoneNo IPR availableGENE3D3.40.50.300coord: 16..233
e-value: 5.5E-21
score: 74.3
NoneNo IPR availableGENE3D3.40.50.300coord: 260..406
e-value: 2.7E-19
score: 68.7
NoneNo IPR availableCDDcd00079HELICccoord: 264..395
e-value: 1.09955E-15
score: 73.426
NoneNo IPR availableCDDcd00046DEXDccoord: 56..174
e-value: 1.18677E-10
score: 58.5028
IPR011991Winged helix-turn-helix DNA-binding domainGENE3D1.10.10.10coord: 407..573
e-value: 1.9E-5
score: 24.1
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 239..399
coord: 42..212

Blast
BLAST of TCONS_00049526-protein vs. Swiss-Prot (Human)
Match: WRN (Werner syndrome ATP-dependent helicase OS=Homo sapiens GN=WRN PE=1 SV=2)

HSP 1 Score: 126.331 bits (316), Expect = 5.700e-30
Identity = 120/457 (26.26%), Postives = 189/457 (41.36%), Query Frame = 0
Query:   13 FLYSMDESTLLKNLAFQFGIEAFHQPQVNVLRAFFNGKHTYFSA-PTGYGKSVVFQAVPRYFEELRPEISNPVLLVFSPLIALINDQIKAAGDSCIMAISLDKTVTDECYEDIKAGTYSLVYACPEVLETKRWRMLFSDSEFVDRCIGVVVDEAHVMVEWGKSSNESTKAFRESYSKIVELQSLLSSKARFMLFTATATSATQATIFSMLNLQSNDVYCEIYHPNKNNVRFTVEQISMGKEDGRYLVNFFDFIMEEIIAKKEHTCKTIIYVNTRKEVNLLNNGMASKLGVDLFLSGKEGNPRYRLVEEFHAYSPQSVKNHVLAQASILESHLRVIICTSAFGMGVNVKGFNRCIHFGPPSTVESFVQEVGRVGRDGSPSESILMF-------HKSLATHASSD------------MVEYAGSHVKCRRDFLMVKF------PGTYSSLSNCTCCDLC 443
            FL+       +  L   FG  +F   Q  V+ +    +    +   TGYGKS+ FQ  P Y           + LV SPLI+L+ DQ+     S I A  L    ++    DIK G Y +VY  PE         L    E       + VDEAH + EWG         FR+S+ K+  L++ L      +  TATA+S+ +  I   LNL++  + C  +  ++ N+   V      ++ G  L +   F+++   +  E    TIIY  +RK    +  G   KL +                  +HA    S +  +      +   ++ +I T AFGMG+N     + IH+G P  +ES+ QE+GR GRDG  S   +++       ++ L T   ++            M +Y  S  +CRR  ++  F        +   +    CCD C
Sbjct:  527 FLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYV--------GKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMG--LLQQLEADIGITLIAVDEAHCISEWGHD-------FRDSFRKLGSLKTALPM-VPIVALTATASSSIREDIVRCLNLRNPQITCTGF--DRPNLYLEVR-----RKTGNILQDLQPFLVK-TSSHWEFEGPTIIYCPSRKMTQQVT-GELRKLNLS--------------CGTYHAGMSFSTRKDI--HHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSS-RCRRQIILSHFEDKQVQKASLGIMGTEKCCDNC 939          
The following BLAST results are available for this feature:
BLAST of TCONS_00049526-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
WRN5.700e-3026.26Werner syndrome ATP-dependent helicase OS=Homo sap... [more]
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