TCONS_00049154-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049154-protein
Unique NameTCONS_00049154-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1287

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049154-protein ID=TCONS_00049154-protein|Name=TCONS_00049154-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1287bp
KSRIPHGCKMVAMEKVTIMERYMQIKKIGEGSFGKALLVKRKEDGKQCVV
KQICISRMSHKEKEESRKEVQLLSKLKHPNIVTYLESFEGSGNLYIVMDY
CEGGDLYQLIVRQRGMHMEESKVLDIFVQCCLAIKYIHDRKILHRDIKTQ
NIFLTRHHIVKLGDFGIARVLKNTMELARTCIGTPYYLSPEIVENRPYNN
KSDIWSLGCVLYELATLKHAFEAGNMKNLVLKICRGSYPPVPPKYSYELR
SLVAHCFKRSPSDRPSINTLLKKPIIQQRISKFLSPEEVEEEFSHTVLHR
QPKPSRAGVAGRPPSAAAGPVKKIVPAKRHGDLVSVYGVSVAKKPAERKP
PSMAPYKRVEKKPANAQGVRSAEKKAVDARERRRKEVLAQEKQYHEHIKK
VQKQRWEKQQAANINRAREGGWKNVLGTDEKDKMKKYQPKAEDKVVVKNK
RYIEPDEKPDQQPLHAWAEQEHQAHRKNLGAVKKENSEDDEREKKEKARM
LDDFWRRKEEAAANKARVSEALAGPRHHNPILDYHENRMKKEKPVVSRPP
IHPGARNPQEAEYLRQLEQIRKQNYKDRQIMRGNTPSVDRPSSNNKVSVA
GDPKVDPDARRRKIQELKEQADRRAAMLKEQLEKRRQQIEKQVEKDRMER
MKKWRQERENCRASPTPQVYQPPKREDNKKEEKKEIAVPSIGMETAMREV
GQPKLFRSLSEGEIHNLVKPQKRENIRRKAWGAADKNAIPSFANIPLEIT
ASAMEATRVIEPTIKNEVEQSFVNQDKNEPRKGWDNQGKTQFVSKLHDMD
LLGTQIPTMTINNIDSKDVPKPGQTITIENKRDVAKPGETIILNKDIPKQ
GETITLEHSANKSSIPNIGGNSNKTIVLSVDKNDVENSKRGEVSPIRQEK
TLNNENQDGSTDSKKLQKLSSNENKEQEPTSQSANEKLEVTQSTNQGSEK
EKFEVDDLEVIEISDNKVETEVSVEDKTNEKTVKNAWSDGVSQKPPESTP
EKLSNIEVNKSPTDTQSRHETSGDSIVEMSEEECSFHTPNRSFGLQSGSY
DIKEKKLLRTCSLPDLRPAALDDVIEEDEENSEEHASDKQESEVKDVKEE
DNENEDEKDESNEDEEEVSDAEADADDDDEFDDYESMLESMRNVLGKTAA
KEATINNNMTLENGQANEQENNEEDEDEDDEWEEERDDEDVSNKNQKNVL
QTNGGDRENLFSRIEESRMALENELGMDLFIKVYRHVQMMQDNEDDELEM
GTTEISQLLGDKENLYQKILYLVIADSAYSEGNDGTF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031232XLOC_031232Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049154TCONS_00049154Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR008271Ser/Thr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 611..649
NoneNo IPR availableCOILSCoilCoilcoord: 1156..1185
NoneNo IPR availableCOILSCoilCoilcoord: 1087..1124
NoneNo IPR availableGENE3D1.10.510.10coord: 118..423
e-value: 4.2E-60
score: 202.4
NoneNo IPR availableGENE3D3.30.200.20coord: 8..117
e-value: 2.2E-29
score: 101.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 572..613
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 295..319
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 650..684
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1058..1137
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 404..496
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 346..380
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1153..1204
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 511..560
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 880..1025
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 22..276
e-value: 6.7E-90
score: 314.7
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 22..275
e-value: 5.2E-68
score: 229.2
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 22..276
score: 51.114
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 142..154
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 28..51
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 18..301

Blast
BLAST of TCONS_00049154-protein vs. Swiss-Prot (Human)
Match: NEK1 (Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2)

HSP 1 Score: 498.049 bits (1281), Expect = 1.380e-154
Identity = 306/738 (41.46%), Postives = 426/738 (57.72%), Query Frame = 0
Query:   19 MERYMQIKKIGEGSFGKALLVKRKEDGKQCVVKQICISRMSHKEKEESRKEVQLLSKLKHPNIVTYLESFEGSGNLYIVMDYCEGGDLYQLIVRQRGMHMEESKVLDIFVQCCLAIKYIHDRKILHRDIKTQNIFLTRHHIVKLGDFGIARVLKNTMELARTCIGTPYYLSPEIVENRPYNNKSDIWSLGCVLYELATLKHAFEAGNMKNLVLKICRGSYPPVPPKYSYELRSLVAHCFKRSPSDRPSINTLLKKPIIQQRISKFLSPEEVEEEF---SHTVLHRQPKPSRAGVAGRPPSAAAGPVKKIV-PAKRHGDLVSVYGVSVAKKPAERKPPSMAPYKRVEKKPANAQGVRSAEKK-AVDARERRRKEVLAQEKQYHEHI----KKVQKQRWEKQQAANINRAREGGWKNVLGTDEKDKMK-------------------KY-----------QPKAED-----KVVVKNKRYIEPDEKPDQQPLHAWAEQEHQAH------RKNLGAVKKENSEDDEREKK-----EKARMLDDFWRRKEEAAANKARVSEALAGPRHHNPILDYHENRMKKEKPVVSRPPIHPGARNPQEAEYLRQLEQIRKQNYKDRQIMRGNTPSVDRPSSNNKVSVAGDPKVDPDARRRKIQELKEQADRRAAMLKEQLEKRRQQIEKQVEKDRMERMKKWRQERENCRASPTPQVYQPPKREDNKKEEKKEIAVPSIGMETAMREVG 701
            ME+Y++++KIGEGSFGKA+LVK  EDG+Q V+K+I ISRMS KE+EESR+EV +L+ +KHPNIV Y ESFE +G+LYIVMDYCEGGDL++ I  Q+G+  +E ++LD FVQ CLA+K++HDRKILHRDIK+QNIFLT+   V+LGDFGIARVL +T+ELARTCIGTPYYLSPEI EN+PYNNKSDIW+LGCVLYEL TLKHAFEAG+MKNLVLKI  GS+PPV   YSY+LRSLV+  FKR+P DRPS+N++L+K  I +RI KFLSP+ + EEF   + +    QP P++   +G+  S +  P +KI  PA ++G +   Y     KK  E+KP  +  +K+  + P          +K + +A  +RR E + +EK+  + I    K  Q +R EK++   INRARE GW+NVL      ++K                   +Y           Q +AED     K  +  +   E    P  +P   +    H         RK L  +K  + + +   +K     E+A+ +++F +RK EA  NKAR    +                                        YL +L QIR QN+ +RQ ++      ++  +N+     G    + D RR+KI+ LK  A+ RAA+LKEQLE++R        K+  ER KK  +E    +   +  V  P  + +      K+     I + +A++EVG
Sbjct:    1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQ-NSISVMPAQKITKPAAKYG-IPLAYKKYGDKKLHEKKP--LQKHKQAHQTPEKRVNTGEERRKISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQRKREAMQNKARAEGHMV---------------------------------------YLARLRQIRLQNFNERQQIKAKLRG-EKKEANHSEGQEGSE--EADMRRKKIESLKAHANARAAVLKEQLERKR--------KEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVG 684          

HSP 2 Score: 93.5893 bits (231), Expect = 4.567e-19
Identity = 74/259 (28.57%), Postives = 125/259 (48.26%), Query Frame = 0
Query: 1043 FGLQSGSYDIKEKKLLRTCSLPDLRPA--ALDDVIEEDEENSEEHASDKQESEVKDVKEED---NENEDEK-DESNEDEEEVSDAEADADDDDEFDDYESMLESMRNVLGKTAAKEATINNNMTLENGQANEQENNEEDEDEDD----------EWEEERDDEDVSNKNQKNVLQTNGGDRENLFSRIEESRMALENELGMDLFIKVYRHVQMMQDNEDDELEMGTTEISQLLGDK-ENLYQKILYLVIADSAYSEGND 1284
             GL +G +D    K+LRTCSLPDL      L DV                   V DV++++   +E EDE   E   D E++   E D D        + +  SM  +L +   +E +      L+N       N  +  DEDD          EW  +  D +++++ + +          ++F+ +EE R+ LE E+G + F +VY  ++ + ++ED+ +E+ +  +  +LG++ ++LY KIL+LV+AD AY E ND
Sbjct: 1033 IGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDV-----------------PTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTD-------LQELQASMEQLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECD----------SVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDND 1257          
The following BLAST results are available for this feature:
BLAST of TCONS_00049154-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NEK11.380e-15441.46Serine/threonine-protein kinase Nek1 OS=Homo sapie... [more]
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