TCONS_00022078-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00022078-protein
Unique NameTCONS_00022078-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length822

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00022078-protein ID=TCONS_00022078-protein|Name=TCONS_00022078-protein|organism=Clytia hemisphaerica|type=polypeptide|length=822bp
SESSHNKKINMASSEEKRDGHNKKINMASSEEKRDEQKNQPQIENNIFGK
QNVKDYSQDVFKDVVKATQNGNAFASLLDEFPYWSSFPEFNEQCKEIGDK
ILNEISELFRHNAVQCGWTTTSRFVDTEERFERLVDGNDIMLESLGTFID
EANGVKKNEKPLVPLNAQSTPIVSSWNKQKNKNSGQSSFKLLLAKNIQRP
QLKWLDKIDNSNTPFTPYIKTKPNAIKPLEEDEMSTEPLSDAVDNFIKQA
RKRNASISAVRHPYEHEISEFEPSEDEIERKDAQMYKSLDETEFHFVETN
EQLTEMHKHLLQAHEVAIDLEHHSYRSFQGFVCLMQISTREKDFVVDTLA
LRXELYILNEVFTDPKILKVLHGADMDIGWLMRDFGLYIVNMFDTGQAAR
TLQEDRFSLAHLLKKHCDVNAQKQYQLADWRIRPLPEEMVRYAREDTHYL
LYIYDCMRNQLMDRGNEMKNLIRSVYSKSASICLSLYEKPRFFTDSHWMA
YQKYRGRLNQQQLECFRLLYEWRDKISREEDESYGYSLPNHMMFQIAENL
PKEPPGVIACCNPVPPLVKQHLIDVHRLVLKAREYDPAENLQVTSDTSRN
IRHEDSYDIDSRLDTGKTGFEIYSIIGPKIEQRIPALSAFEAMVKEHIEL
TEGKRKAKELLSILTSPFQQYLPNTGVPVKHPDQINKKWKEAITTKTTEN
PKIPTIEIESSSDDNVKLQSGNKKRKSDESEQEVQEVTIREMISGKRQKT
SDDEMTYEDTVKDSSEYVPFDYSKANMRKFAANKKKNSQTEKPTIIQEPN
KGKAMKTKVKNKSANQTMSFQR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012379XLOC_012379Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00022078TCONS_00022078Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR0025623'-5'_exonuclease_dom
IPR002121HRDC_dom
IPR012588Exosome-assoc_fac_Rrp6_N
IPR012337RNaseH-like_dom
IPR010997HRDC-like
Vocabulary: Biological Process
TermDefinition
GO:0006139nucleobase-containing compound metabolic process
GO:0006396RNA processing
GO:0044237cellular metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:00084083'-5' exonuclease activity
GO:0003676nucleic acid binding
GO:0003824catalytic activity
GO:0000166nucleotide binding
Vocabulary: Cellular Component
TermDefinition
GO:0005622intracellular
GO:0000176nuclear exosome (RNase complex)
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0044237 cellular metabolic process
biological_process GO:0006139 nucleobase-containing compound metabolic process
biological_process GO:0006396 RNA processing
cellular_component GO:0005622 intracellular
cellular_component GO:0000176 nuclear exosome (RNase complex)
molecular_function GO:0008408 3'-5' exonuclease activity
molecular_function GO:0003824 catalytic activity
molecular_function GO:0003676 nucleic acid binding
molecular_function GO:0000166 nucleotide binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0025623'-5' exonuclease domainSMARTSM0047435exoneu6coord: 294..462
e-value: 5.7E-47
score: 172.0
IPR0025623'-5' exonuclease domainPFAMPF01612DNA_pol_A_exo1coord: 295..461
e-value: 2.5E-46
score: 157.5
IPR002121HRDC domainSMARTSM00341hrdc7coord: 509..589
e-value: 8.5E-13
score: 58.5
IPR002121HRDC domainPFAMPF00570HRDCcoord: 512..577
e-value: 1.3E-11
score: 44.2
IPR002121HRDC domainPROSITEPS50967HRDCcoord: 509..589
score: 14.587
IPR012588Exosome-associated factor Rrp6, N-terminalPFAMPF08066PMC2NTcoord: 65..154
e-value: 3.6E-12
score: 46.7
NoneNo IPR availableGENE3D1.10.150.80coord: 495..595
e-value: 9.6E-19
score: 66.6
NoneNo IPR availableCDDcd06147Rrp6p_like_exocoord: 290..479
e-value: 4.14375E-117
score: 354.211
IPR012337Ribonuclease H-like domainGENE3D3.30.420.10coord: 292..481
e-value: 9.8E-44
score: 148.6
IPR012337Ribonuclease H-like domainSUPERFAMILY53098Ribonuclease H-likecoord: 197..491
IPR010997HRDC-likeSUPERFAMILY47819HRDC-likecoord: 492..589

Blast
BLAST of TCONS_00022078-protein vs. Swiss-Prot (Human)
Match: EXOSX (Exosome component 10 OS=Homo sapiens GN=EXOSC10 PE=1 SV=2)

HSP 1 Score: 568.155 bits (1463), Expect = 0.000e+0
Identity = 318/851 (37.37%), Postives = 477/851 (56.05%), Query Frame = 0
Query:   49 GKQNVKDYSQDVFKDVVKATQNGNAFASLLDEFPYWSSFPEFNEQCKEIGDKILNEISELFRHNAVQCGWTTTSRFVDTEERFERLVDGNDIMLESLGTFIDEANGVKKNEKPLVPLNAQ-STPIVSSWNKQK---NKNSGQSSFKLLLAKNIQRPQLKWLDKIDNSNTPFTPYIKTKPNAIKPLEE---DEMSTEP--------LSDAVDNFIKQARKRNASISAVRHPYEHEISEFEPSEDEIERKDAQMYKSLDETEFHFVETNEQLTEMHKHLLQAHEVAIDLEHHSYRSFQGFVCLMQISTREKDFVVDTLALRXELYILNEVFTDPKILKVLHGADMDIGWLMRDFGLYIVNMFDTGQAARTLQEDRFSLAHLLKKHCDVNAQKQYQLADWRIRPLPEEMVRYAREDTHYLLYIYDCMRNQLMDRGNEMKNLIRSVYSKSASICLSLYEKPRFFTDSHWMAYQKYRGRLNQQQLECFRLLYEWRDKISREEDESYGYSLPNHMMFQIAENLPKEPPGVIACCNPVPPLVKQHLIDVHRLVLKAREYDPAENLQVTSDTSRNIRHEDSYDIDSRLD-----------TGKTGFEIYSIIGPKIEQRIPALSAFE---------AMVKEHI---------------ELTEGKRKAKELLSILTSPFQQYLPNTGVPVKHPDQINKKWKEAITTKTTENP---KIPTIEIESSSDDNVKLQSGNKKRKSDE-----SEQEVQEVTIREMI-----SGKRQKTSDDEMTYE---------------DTVKDSSEYVPFDYSKANMRKFAANKKKNSQTEKPTIIQEPNKGKAMKTKVKNKS-ANQTMSF 820
            G  +   + +     VV  T+         DE+ ++ SFP F   C+  GD++L  +S + +++  +      S+  + E++F+ LVD ND++LE +G  +DEA+GV KN++P++P   Q    +VSSWN++     K +   +F+LL AKNI RPQLK+ +KIDNSNTPF P I  KPNA KPL +    E    P        +  A+ +FI Q R +        HPY++E++ F P++  +++   Q+Y+ ++ET  HF+ + ++L E+++ LL   E A+DLEHHSYRSF G  CLMQISTR +DF++DTL LR ++YILNE  TDP I+KV HGAD DI WL +DFGLY+VNMFDT QAAR L   R SL HLLK +C+V++ KQYQLADWRIRPLPEEM+ YAR+DTHYLLYIYD MR ++ +RGN     ++ V+ +S  ICL  + KP F  +S+   Y+K +  LN QQL  F+LL+ WRDK +R EDESYGY LPNHMM +IAE LPKEP G+IACCNPVPPLV+Q + ++H L+ +ARE        + S+ +  ++         RL+               G+ I    G    Q+  +L   E          ++   +                LT  ++KA+ ++    +PF+ +LP+ G    H   +++  K   +TK  E     K+  ++++  S + VK ++  +    ++          Q +++R+ +     + KR++ + D  T E               D      E+ P+DYS+++ + FA N K    ++     Q P+  K +  K   +S  N++MSF
Sbjct:   28 GFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVILERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNIIRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVELNEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMP-----LLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLG----HRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSF 869          
The following BLAST results are available for this feature:
BLAST of TCONS_00022078-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
EXOSX0.000e+037.37Exosome component 10 OS=Homo sapiens GN=EXOSC10 PE... [more]
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