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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00020301-protein ID=TCONS_00020301-protein|Name=TCONS_00020301-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1190bp
MVMRKLSVPTRPPAMDWRHQRAIVLSSQAGDLVTALPKGVNDDYENNNGF
NVSQQNGGTVGVFTAVNAAESSIREDRRLRDNDEDIEYSEEVSGPYHLPQ
IMHASVDRLIERLADPRLPGAEFMETFLLTYRAFTTSDIVIRGLIEAYWK
VMGGYPTPKKSNSPERKKLAVSRSLSSGHPRSRLRSNASDASSTDDLDAS
FNSGISPCGASTTVFNYSTLKDQLNSPAKRNVAATTKWCQDSAAVTAAEK
PFSEKLRSASASNIGPIPNELTVEPNGTDARKISRSHSIEVIYDKNDTNA
KKSSFVSAVTSKSCDQIDDPSAFSGDPLNKKVNILSIVLNKENRPSTNNE
NKENIPEIILNGHNDQINNNDIKFSSHENSLSASLNSSQLSASLNQSQLS
TSLNQSDLSCVSDASTLYENGQLSNESFDGEVIPNDDEHCGEGFMDEGPS
ILEDVVEEDDHMIISASLDSTGRAPNSIAISLDDSYLEDGERRSTMESNT
TLNSSNDKSDIFSLDRSVTMDSMNSFASSDISTEQRSDGETSSSNAGSRS
VVHSHSDELICKQREAETITLPPKSASLSEKKSGISPYFRRKNKGKKEKA
ERKQKAKSMADILSDEPVLVSIKETGDGRMIFDDSQSLYEEVRPLESPVT
ENKTFESSSIPIPVPAPAHVTKKSPNSTPKRKRSLYFQKVFNKVTVRRAA
SEQNLSDMSPTTPTSEMKPALSAMSLELNGNANGHLPKVSPKDHHPDFEM
GTRSLERKKNAPSLRERLSAFTQLSSSEMDIHKAGLNSDNKNTLKKEKKK
FKNSLRILSASPKETTPSQSPIRRKTSTSVIEKSTRPQLVTRKSISINRG
PLKIMSIFKHWLAKHPKDFLSDPEMITILEKFFDDIKSDERTLPVVKEIV
GSLEKSVVSHRKSLAAVHPFDELLLQQHSLRNVQQSDINEEEELNKCTQL
HAHPPNIVAANMTLLEHYLYSKISFNEFVSCQWTKKDKNERAPGIMRFID
RFNHVTSIISYGVVHGSTIEYRSQIIEFWIKTAAHCRDLNNFNACVEIVS
ALNASAVHRLKKSWEQVSKPLREVFNDLDTLVSADRSFKNLREAVHMCNP
PCVPYLGCYLSDLLFAHEGGKTFNGGGLVNFAKMCRVSRLVREVKCYQQL
PYTLELNKEVAFSLVNWDVEVNQDLLYDQSLLAEPRESSR Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0007264 | small GTPase mediated signal transduction |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0007264 |
small GTPase mediated signal transduction |
| molecular_function |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain | SMART | SM00147 | RasGEF_3 | coord: 950..1187
e-value: 1.7E-73
score: 260.2 |
| IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain | PFAM | PF00617 | RasGEF | coord: 958..1134
e-value: 3.5E-51
score: 173.8 |
| IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain | GENE3D | 1.10.840.10 | | coord: 938..1190
e-value: 8.8E-76
score: 254.4 |
| IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain | PROSITE | PS50009 | RASGEF_CAT | coord: 954..1186
score: 64.4 |
| IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain | CDD | cd00155 | RasGEF | coord: 958..1181
e-value: 2.88131E-66
score: 223.283 |
| IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal | PFAM | PF00618 | RasGEF_N | coord: 100..168
e-value: 5.0E-12
score: 45.9 |
| IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal | PROSITE | PS50212 | RASGEF_NTER | coord: 97..225
score: 12.029 |
| None | No IPR available | GENE3D | 1.20.870.10 | | coord: 69..937
e-value: 1.7E-14
score: 53.4 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 810..829 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 156..196 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 649..682 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 490..509 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 729..763 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 570..607 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 527..557 |
| IPR019804 | Ras guanine-nucleotide exchange factor, conserved site | PROSITE | PS00720 | RASGEF | coord: 1103..1133 |
| IPR023578 | Ras guanine nucleotide exchange factor domain | SUPERFAMILY | 48366 | Ras GEF | coord: 81..151
coord: 836..1189 |
Blast
BLAST of TCONS_00020301-protein vs. Swiss-Prot (Human)
Match: RGRF1 (Ras-specific guanine nucleotide-releasing factor 1 OS=Homo sapiens GN=RASGRF1 PE=1 SV=2) HSP 1 Score: 225.713 bits (574), Expect = 4.354e-60 Identity = 124/377 (32.89%), Postives = 208/377 (55.17%), Query Frame = 0
Query: 814 ETTPSQSPIRRKTSTSVI----EKSTRPQLVTRKSISINRGPLKIMSIFKHWLAKHPKDFLSDPEMITILEKFFDDIKSDERTLPVVKEIVGSLEKSVVSHRKSLAAVHPFDELLLQQHSLRNVQQSDINEEEELNKCTQLHAHPPNIVAANMTLLEHYLYSKISFNEFVSCQWTKKDKNERAPGIMRFIDRFNHVTSIISYGVVHGSTIEYRSQIIEFWIKTAAHCRDLNNFNACVEIVSALNASAVHRLKKSWEQVSKPLREVFNDLDTLVSADRSFKNLREAVHMCNPPCVPYLGCYLSDLLFAHEGGKTFNGGGLVNFAKMCRVSRLVREVKCYQQLPYTLELNKEVAFSLVNWDVEVNQDLLYDQSLLAEPR 1186
E TP++ RR + S +++ + V R++ + NR ++++ +HW++KH +DF ++ E+ + F +++ D E++ K+ + ++L P D + +I + E K H +A +TLL+H ++ KI + EF W K +KNER P IM+ FN ++++I+ ++ I R IE W+ A CR L+N+NA +EI S++N SA+ RLKK+W +VSK + + + L LVS++ FKNLREA+ C+PPCVPYLG YL+DL F EG + GLVNF+KM +S ++RE++ +QQ Y +E +V L++ ++++ LY+ SL EP+
Sbjct: 915 EGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRA-ATNR----VLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHD-------PELLTQERKAAANIIRTLTQEDPGDN---------QITLEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPK 1270
The following BLAST results are available for this feature:
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