TCONS_00018469-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00018469-protein
Unique Name	TCONS_00018469-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	518

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00018469-protein ID=TCONS_00018469-protein|Name=TCONS_00018469-protein|organism=Clytia hemisphaerica|type=polypeptide|length=518bp
MAIQRFLLLLLTLNVLFPICFTDDSHNMHEEAMSDGISPIFITPEMYLHA
HLFPRDEQKRPQPQRFHPHYERPVQVNLTIALISIVDIEPQNEVIIINAN
FEQSWFNPSMSWDPHNFAGIKKINVRSGMTWVPDIFVHANVENDKKYNGL
MDKVNTYVKVNHEGLHTWNAAVTLRMGCGMNIENYPFDTQKCPLRFGSLS
MDATRMKLVPKPINLKSYGASPEWIFISMDHVGEEKSYPGSDHPHTTAVY
TVAMRRKALYPITMLILPNLILAGLTILVFSIPTPTGERAMYIFTIFLAV
AWYMTSNIETMPSSSQTIPLYTKFLAINLISLSLLCISLCFTIVCFYTDP
QISDMPGWIRVNILGHGAKFFGMDVDKKVSEWREELCEARQYDHLLPEEY
EPDQEGEVQAEEGNEKAPGDLWVDCSKPEAGALMNIFNPVEMRQVHLLIE
DYLRRLEEIEDSKWAQREWELVAQILDKAFLYVFSSALTLTVVSCSIHIL
NXSTAMEFHCISNHTPLE

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_010346	XLOC_010346	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00018469	TCONS_00018469	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Molecular Function**
Term	Definition
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 265..490 e-value: 2.1E-16 score: 60.6
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 262..490
None	No IPR available	GENE3D	1.20.58.390		coord: 265..507 e-value: 1.6E-19 score: 69.5
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 42..264 e-value: 8.6E-48 score: 162.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 67..257 e-value: 3.1E-34 score: 118.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 69..257
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 178..192

Blast

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BLAST of TCONS_00018469-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 156.377 bits (394), Expect = 7.329e-42
Identity = 114/453 (25.17%), Postives = 205/453 (45.25%), Query Frame = 0

Query:   71 ERPVQVNLTIALISIVDIEPQNEVIIINANFEQSWFNPSMSWDPHNFAGIKKINVRSGMTWVPDIFVHANVENDKKYNGLMDKVNTYVKVNHEGLHTWNAAVTLRMGCGMNIENYPFDTQKCPLRFGSLSMDATRMKLVPKPINLKSYGASPEWIFISMDHVGEEKSYPGSDHPHTTAVYTVAMRRKALYPITMLILPNLILAGLTILVFSIPTPTGERAMYIFTIFLAVAWYMTSNIETMPSSSQTIPLYTKFLAINLISLSLLCISLCFTIVCFYTDPQISDMPGWIRVNILGHGAKFFGMDVDKKVSEWR-EELCEARQYDHLLPEEYEPDQEGEVQAEEGNEKAPGDLWVD----CSKPEAGALMNIFNPVEMRQVHLL--------IEDYLRRLEEI----------EDSKWAQREWELVAQILDKAFLYVFSSALTLTVVSCSIHIL 500
             +P+ V  +++L+ I+D++ +N+V+  N   + SW +  + W+   + G+K +    G  W PDI ++ +   D++++      +T V VN  G   +      +  C +++  +PFD Q C L+FGS S     + L  +  ++  Y  + EW  + +     E+ Y     P+    +TV MRR+ LY    L++P ++++ L +LVF +P  +GE+     T+ L++  +M    E MP++S ++PL  ++ A  +I + L  +     +   + DP    MP W RV +L   A F  M   K+  E +    C+ +Q    L    E        A  GN    G   +D       P++G +            HLL          D  + LEE+          ++S+    EW+  A ++D+  L  FS     T++ C+I IL
Sbjct:   48 SQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA--DERFDATF---HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRM---KRPGEDKVRPACQHKQRRCSL-ASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFS---VFTII-CTIGIL 487

The following BLAST results are available for this feature:

BLAST of TCONS_00018469-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00018469-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA7	7.329e-42	25.17	Neuronal acetylcholine receptor subunit alpha-7 OS...	[more]

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TCONS_00018469-protein (polypeptide) - C. hemisphaerica