TCONS_00018202-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00018202-protein
Unique NameTCONS_00018202-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length770

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00018202-protein ID=TCONS_00018202-protein|Name=TCONS_00018202-protein|organism=Clytia hemisphaerica|type=polypeptide|length=770bp
MFTSKARTAIQRFVLPKNNVGFSLTSLHRGYAQAAAATAPGGRDIVNYTV
ENNVAVVTIDDPSAKVNTLSDKVMNETVDVLTEVTHNPNVKSVVLMSGKP
DCFIAGADIKMLGKAESVADGTEISRSGQKILGMLADSKKPIVAAISGSC
LGGGLEVALACQYRVALDNPKTGLGVPEVMLGLLPGAGGTQRLPQLVGLP
TSLDMMLTGKTIKAAKAKKLGLVDKVVEELGVGVRTQKDNSLNHLRKVAI
QTAQQLGDGKLRVNRDKSWASMKGLQHNAPMKIGPLRDFVFKKAEETVMK
KTLGLYPAPLKILEAAKVGLEKGAEAGYEQEAKGFGELTQSNEANSLMGL
FHGQVECKKNPFGVPSKRSQNIAVLGAGLMGAGIAEVSIQKAKHDVILKD
TTVEGLSRGINQVYGNMNKRTKKRQMTTFERDNIMARMDSQLDYSGFENA
DMVIEAVFEDINIKHKVVKEVEAVTPDHCIFASNTSALPISEIAAASSRP
ENVIGMHYFSPVDKMPLLEIIVTDKTTKDVTANAVDVGLKQGKTVIVVKD
GPGFYTTRILMPTLQEALCLLQEGYDPKDLDKRSKGFGFPVGCITLVDEV
GIDVAAHIGAHLGQVFEKRMVGADFHLLQDMVDRGYCGRKTKKGFFKYSG
KREVNEGALEVIKKYQTAKVEGLTDEETALRLISRMVNESVLCLEEDILR
NPVDGDIGAVFGLGFPPPHGGPFRFVDAYGAGNLVKLMEKYQQKIGEAQF
TPCQLLLDHAKDSSKRFHKK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_010230XLOC_010230Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00018202TCONS_00018202Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001753Crotonase_core_superfam
IPR0133286PGD_dom_2
IPR012803Fa_ox_alpha_mit
IPR0061083HC_DH_C
IPR0061763-OHacyl-CoA_DH_NAD-bd
IPR018376Enoyl-CoA_hyd/isom_CS
IPR0089276-PGluconate_DH_C-like
IPR029045ClpP/crotonase-like_dom
IPR016040NAD(P)-bd_dom
Vocabulary: Biological Process
TermDefinition
GO:0008152metabolic process
GO:0055114oxidation-reduction process
GO:0006635fatty acid beta-oxidation
GO:0006631fatty acid metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0016491oxidoreductase activity
GO:00038573-hydroxyacyl-CoA dehydrogenase activity
GO:0004300enoyl-CoA hydratase activity
Vocabulary: Cellular Component
TermDefinition
GO:0005739mitochondrion
GO:0016507mitochondrial fatty acid beta-oxidation multienzyme complex
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006635 fatty acid beta-oxidation
biological_process GO:0006631 fatty acid metabolic process
biological_process GO:0008152 metabolic process
biological_process GO:0055114 oxidation-reduction process
cellular_component GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex
cellular_component GO:0005739 mitochondrion
molecular_function GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
molecular_function GO:0003824 catalytic activity
molecular_function GO:0004300 enoyl-CoA hydratase activity
molecular_function GO:0016491 oxidoreductase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001753Crotonase superfamilyPFAMPF00378ECH_1coord: 51..255
e-value: 3.7E-42
score: 144.3
IPR0133286-phosphogluconate dehydrogenase, domain 2GENE3D1.10.1040.10coord: 553..653
e-value: 2.8E-22
score: 78.8
IPR0133286-phosphogluconate dehydrogenase, domain 2GENE3D1.10.1040.10coord: 678..770
e-value: 1.9E-16
score: 60.0
NoneNo IPR availableGENE3D3.90.226.10coord: 24..258
e-value: 5.0E-53
score: 179.0
NoneNo IPR availableGENE3D3.40.50.720coord: 314..552
e-value: 2.5E-52
score: 177.3
NoneNo IPR availableCDDcd06558crotonase-likecoord: 46..229
e-value: 1.37982E-50
score: 174.671
IPR012803Fatty acid oxidation complex, alpha subunit, mitochondrialTIGRFAMTIGR02441TIGR02441coord: 37..767
e-value: 0.0
score: 1038.2
IPR0061083-hydroxyacyl-CoA dehydrogenase, C-terminalPFAMPF007253HCDHcoord: 553..648
e-value: 4.5E-22
score: 78.4
IPR0061763-hydroxyacyl-CoA dehydrogenase, NAD bindingPFAMPF027373HCDH_Ncoord: 371..550
e-value: 5.6E-54
score: 182.6
IPR018376Enoyl-CoA hydratase/isomerase, conserved sitePROSITEPS00166ENOYL_COA_HYDRATASEcoord: 143..163
IPR0089276-phosphogluconate dehydrogenase C-terminal domain-likeSUPERFAMILY481796-phosphogluconate dehydrogenase C-terminal domain-likecoord: 673..763
IPR0089276-phosphogluconate dehydrogenase C-terminal domain-likeSUPERFAMILY481796-phosphogluconate dehydrogenase C-terminal domain-likecoord: 552..653
IPR029045ClpP/crotonase-like domainSUPERFAMILY52096ClpP/crotonasecoord: 44..359
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 369..552

Blast
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BLAST of TCONS_00018202-protein vs. Swiss-Prot (Human)
Match: ECHA (Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens GN=HADHA PE=1 SV=2)

HSP 1 Score: 820.076 bits (2117), Expect = 0.000e+0
Identity = 411/747 (55.02%), Postives = 545/747 (72.96%), Query Frame = 0 
Query:   29 RGYA--QAAAATAPGGRDIVNYTVENNVAVVTIDDPSAKVNTLSDKVMNETVDVLTEVTHNPNVKSVVLMSGKPDCFIAGADIKMLGKAESVADGTEISRSGQKILGMLADSKKPIVAAISGSCLGGGLEVALACQYRVALDNPKTGLGVPEVMLGLLPGAGGTQRLPQLVGLPTSLDMMLTGKTIKAAKAKKLGLVDKVVEELGVGVRTQKDNSLNHLRKVAIQTAQQLGDGKLRVNRDKSWASMKGLQHNAPMKIGPLRDFVFKKAEETVMKKTLGLYPAPLKILEAAKVGLEKGAEAGYEQEAKGFGELTQSNEANSLMGLFHGQVECKKNPFGVPSKRSQNIAVLGAGLMGAGIAEVSIQKAKHDVILKDTTVEGLSRGINQVYGNMNKRTKKRQMTTFERDNIMARMDSQLDYSGFENADMVIEAVFEDINIKHKVVKEVEAVTPDHCIFASNTSALPISEIAAASSRPENVIGMHYFSPVDKMPLLEIIVTDKTTKDVTANAVDVGLKQGKTVIVVKDGPGFYTTRILMPTLQEALCLLQEGYDPKDLDKRSKGFGFPVGCITLVDEVGIDVAAHIGAHLGQVFEKRMVGADFHLLQDMVDRGYCGRKTKKGFFKYS---GKREVNEGALEVIKKYQT-AKVEGLTDEETALRLISRMVNESVLCLEEDILRNPVDGDIGAVFGLGFPPPHGGPFRFVDAYGAGNLVKLMEKYQQKIGEAQFTPCQLLLDHAKDSSKRFHK 769
            RGY       ++A   R  +NY V+ +VAVV I+ P++KVNTLS ++ +E  +V+ E+  +  ++S VL+S KP CFIAGADI ML   +++ + T++S+  Q+I+  L  S KPIVAAI+GSCLGGGLEVA++CQYR+A  + KT LG PEV+LG LPGAGGTQRLP++VG+P +LDMMLTG++I+A +AKK+GLVD++VE LG G++  ++ ++ +L +VAI  A+ L D K+   RDK    ++ L   A M I  +R  V+KK EE V K+T GLYPAPLKI++  K G+E+G++AGY  E++ FGEL  + E+ +LMGL+HGQV CKKN FG P K  +++A+LGAGLMGAGIA+VS+ K     ILKD T+  L RG  QV+  +N + KK+ +T+FERD+I + +  QLDY GFE ADMVIEAVFED+++KH+V+KEVEAV PDHCIFASNTSALPISEIAA S RPE VIGMHYFSPVDKM LLEII T+KT+KD +A+AV VGLKQGK +IVVKDGPGFYTTR L P + E + +LQEG DPK LD  +  FGFPVG  TLVDEVG+DVA H+   LG+VF +R  G +  LL  MV +G+ GRK+ KGF+ Y     ++++N     ++   +   K E  +DE+   RL++R VNE+V+CL+E IL  P +GDIGAVFGLGFPP  GGPFRFVD YGA  +V  ++KY+   G+ QFTPCQLL DHA   +K+F++
Sbjct:   22 RGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGL--VEKLTAYA-MTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKG-LKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGK-QFTPCQLLADHANSPNKKFYQ 763
The following BLAST results are available for this feature:
BLAST of TCONS_00018202-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ECHA0.000e+055.02Trifunctional enzyme subunit alpha, mitochondrial ... [more]
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