Putative cnidarian restricted protein (polypeptide) - C. hemisphaerica

Overview
NamePutative cnidarian restricted protein
Unique NameTCONS_00016849-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length3373

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00016849-protein ID=TCONS_00016849-protein|Name=Putative cnidarian restricted protein|organism=Clytia hemisphaerica|type=polypeptide|length=3373bp
MKGCVIFGLVLVAYVLGETIIEDGCGPKSPFAPCNRDFCEEAQCPNYPLA
ECRLNICGTCKAVFYVNDREVDCHGDSGSVVNQGSGALGGPEIPRTTLAT
LKFEDRCQPGVGIVPCTKNPCLKARCEGQRGAECRVNLCGQCSAVFYFNN
QKVTCENAIDRSSLTRCQYDRHIDLRNRHKDNFIVDCDANGQYKPLQCWN
SVGLCWCVRPEDGTEIFGSRTYFPNKPRCDVIDTAKQCEDTEFGCCQDLK
TPAQGPNGKGCPRQASKCEILQQRASTGFIGAFTPQCDSKGQFEKIQCWN
AIGHCWCVDNDGRELEGTRAEGQQPDCTAVVCEDKRDDCRKYASVPGFCQ
RISHYMKEYCRKSCGFCNGVVNPEKYIAERPGCNSPFGCCDDYISSSKGP
NDYMCPLYKTSCDMPKVSGNCEGNFQRYYYDQLTNECKLFVYGGCRGNKN
NYISQGKCEQECVQEIQPTEAPLSTTPVITFQPKITTDPKDITDPCEMPL
QRGTCDSGSVTADQRYYFNKVNGECQVFAFGGCDSNENNFLSKSECENMC
IYRKVTTPSINEVTDGLGGPSLKEGCGHAYGCCEDGVTPSLGPDFEGCPV
YESYCMMPAATGPCREYLPRYYYNHETGQCELFVYGGCGGNNNRFYTPQE
CYRDCYLNQQGKTNPPTKSTSTKRQSTTQQFVTSTPQPTTEQSTMQTDSL
QTTIESTVAPKTTLSPTDDVVTTVSTTTTKTRQPTTTTTTTTPGTTTTKK
PLTECQRRRIVSSNINRDPNNSKVYMPKCTYNGQFEKVQCFNDVKKCWCV
DVDGNEIEGTRGTEYPACPKRPVDQYKSNCQDKQPVKCLEYASPGYCKRY
KSFMGTMCPKSCGFCTDTPVVARPGCKSDLGCCRDGITPKQNGVLCPKFK
SICEMPKNTGQCFGYMIRYYFNVETQKCEQFAYGGCDGNSNNFFTLVECQ
QRCGKVATTVASTTKTSTTTTTLKPTTEEIRQTTVVTEGLETDEPEVATA
RPQPTEEVAKTTESTERSTTESLSTKTSSPVDRVRTSEQSTESVRSTVAT
EDLQTTEQKRQTEITTQMPQTEYVSTTQETRTDDLITKDLITDPIRTEEE
RTTESYTTHDVDKLVVVTTQATPTTQQQQTTVDDVDQRRVSTTEDLYVLS
TQQTEGPDAKVVTDFRTEQSTTQEPDFKTTEQVLTTAAQTTTDSPKSTLP
KPSEGPHTPLVITEGSTSERTTDSPTDEITTDSESEQTTTKDKIETDAPQ
LTTTSSPEVSTESKQTTDFVEGSISTTTQQQTTKNIQTESPKSTSLPTKQ
DSTQKPITMKAKSTTGQPAVTGDLEERTEASTTQETVTASVTSTTQKQGK
VSTQPLEQVSTNEATKTQQTGSVSTQEPKTQQTEAATTPLPERDSTTEEV
LTQQTESATTQQAQTEIVSTQEPATQQTDSVTPQVQTEEQRTDSTTPLPE
RTTTQEPSTEQTEAALTDSGIQQTDLVTTQKPSTQQTDVVTQQTESITTE
EPVTQQTEIVTTEQVETDVVPTKQTNTVVTQQQTETVTTQQPQTEQTESA
TTQEIVTDAPQVVTTQEKELSTEKYTTQQTEEIITQQPGSATKGTDSPKT
TEEPATQQTDLVTTQEPATKQTDSVTTQEPATKQTDSVTTQEPATKQTDS
VTTQEPATQQTDSVTTQKPATQQTDSVTTQELATQQTDYVTTQEPATQQT
DSVTTQEPATKRTDSVTTQGPATQQTDSVTTQQPVTQQTDSVTTQEPATK
QTDLVTTQEPATKQTDSVTTQEPATKQTDLVTTQEPATKQTDSVTTQQPV
TKQTDSVTTQKPATKQTDSVTTQQPVTKQTHSVTTQQPVTQQTDSVTTQQ
SAAPQTQSITDVTDITESATTQAPQTEKTEIVTTQETVTEQTDSPTTRQT
MTEATEVMTTQQTEQITEITKSATTQQPETDAPLVVSTQVPAPTTTTDPS
ASTRQTVEVVTEQTETGPTEKVATVSQTTPSPKPSETPEDVTVYVTVSST
GEKTETRTTPEPKATTEEAQVSTTKKVATDVSTQTETVITQQITTTQQPS
KAPESVSSTEGKTESESTQNIALSTQKPTELASTEELKTKDVSTQQTVSV
STQEPKTGQTEATTTPLPERESTTEEMLTQQTKSATTQQVQTEAATTGQT
ELATDSKTTDEIKEISTETPQTESTEQETTQGTIVEVTQPDVTAATTQQP
TAVSTQTEASDVTTKARESVTTQESVTSHQTESASTQEQVTAQQTEAQTT
QVTATQESVTTEAKITESPTTQESVTQESETTESATTEGPIVTKDITTGE
SVVTKEPRTSTTKEPVSPIVIVEGEDNNNVGKATTTTTTASTTLVKIVTK
EAVTETLKTLPDEKQVQTEAVETTVAPTTTSTTEANGITEVVKTTQQPEA
ETTVAVTREITDLATTVEPETESVKTTQQTENTVAQSTTAIMKEVTAALT
ETITSTTQKPLTEQTESFTQKTEAVKSTQQTEEIATQEPTTEQTEALATK
EVVTTEQTEAVTTQQIEQTTSTTKSTISATTNIQTEKNDDTATLAPLVEK
TVPTETEATEKVTTQQTEAASTQQTEAVATQQTEVASNQQTGAVSTQQTE
AGTTQQTEAATTQQTEIASTQQIEVASTQQTEAATTQQTEETSTQQNEEA
STQQPGAASTRQTEAATTQQTEAVATQQAEVASNQQTGAVSTQQTETEGT
ESVSTQQTEVASTQQPGAASTRQTEVVSTQQTEASNAQQTDAEVTTTQQP
KTYETTESLATQGLKTEAPTTTLTTEFATTQQTEAVATQQAEVASNQQTG
AVSTQQTETEGTESVSTQQTEVASTQQPGAASTRQTEVVSTQQTEASNAQ
QTDAEVTTTQQPKTYETTESLATQGLKTEAPTTTLTTEFATTQQTEAVAT
QQAEVASNQQTGAVSTQQTETEGTESVSTQQTEVASTQQPGAASTRQTEV
VSTQQTEASNAQQTDAEVTTTQQPKTYETTESLATQGLKTEAPTTTLTTE
FATTQQSTTIIGNDLQPTATLLATISMKEACLTPPEKGDCEQYFPRYYFD
TSVNKCRPFGYSGCKGNGNNFVTQKECETKCQYAINTLAPTTTTVTMTTE
QATDATTEDPLFEEVEGRIIKKTDGELGENNGFQACGSDHGCCEDLITPA
KGPNGEGCPQYKSRCEYPPNRGPCRAAISRWYYNHRNKSCEMFTFGGCQP
NGNNFDSEDLCYEACQSGDNFIDETLTDTGLSETYETVEALVIPGCPSNS
GRYGCCVDGITPAQGPNQQGCPEYKSECDMPAVTGGGNDRLIRYYYNPSK
KECESFAYSGKGGNRNNFISQQACERRCSENSDSVSIECRDVINTCDEFK
RKGYCSRRIVSSTYCRKTCKTCT
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_009435XLOC_009435Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00016849TCONS_00016849Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002223Kunitz_BPTI
IPR000716Thyroglobulin_1
IPR003582ShKT_dom
IPR020901Prtase_inh_Kunz-CS
Vocabulary: Molecular Function
TermDefinition
GO:0004867serine-type endopeptidase inhibitor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0004867 serine-type endopeptidase inhibitor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002223Pancreatic trypsin inhibitor Kunitz domainPRINTSPR00759BASICPTASEcoord: 602..616
score: 34.47
coord: 938..953
score: 48.23
coord: 630..640
score: 65.7
IPR002223Pancreatic trypsin inhibitor Kunitz domainSMARTSM00131KU_2coord: 494..551
e-value: 8.8E-17
score: 71.8
coord: 3276..3329
e-value: 1.2E-20
score: 84.5
coord: 3163..3216
e-value: 1.0E-17
score: 74.9
coord: 901..954
e-value: 1.2E-23
score: 94.6
coord: 3029..3082
e-value: 3.6E-21
score: 86.3
coord: 603..656
e-value: 1.5E-21
score: 87.6
coord: 410..463
e-value: 2.2E-17
score: 73.8
IPR002223Pancreatic trypsin inhibitor Kunitz domainGENE3D4.10.410.10coord: 407..466
e-value: 3.3E-17
score: 62.0
IPR002223Pancreatic trypsin inhibitor Kunitz domainGENE3D4.10.410.10coord: 474..565
e-value: 3.6E-17
score: 62.1
coord: 3101..3230
e-value: 1.7E-18
score: 66.4
coord: 569..670
e-value: 1.5E-20
score: 73.1
IPR002223Pancreatic trypsin inhibitor Kunitz domainGENE3D4.10.410.10coord: 3260..3331
e-value: 1.1E-18
score: 66.7
coord: 3013..3084
e-value: 1.6E-19
score: 69.4
coord: 884..956
e-value: 1.2E-20
score: 73.0
IPR002223Pancreatic trypsin inhibitor Kunitz domainPFAMPF00014Kunitz_BPTIcoord: 3165..3216
e-value: 2.3E-14
score: 53.3
coord: 3030..3082
e-value: 6.6E-16
score: 58.2
coord: 496..550
e-value: 1.7E-14
score: 53.6
coord: 902..953
e-value: 1.7E-16
score: 60.0
coord: 3278..3328
e-value: 1.3E-15
score: 57.2
coord: 412..462
e-value: 1.2E-14
score: 54.1
coord: 605..655
e-value: 1.8E-16
score: 60.0
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 496..550
score: 14.222
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 3031..3081
score: 15.407
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 3278..3328
score: 13.216
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 903..953
score: 15.696
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 605..655
score: 15.796
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 3165..3215
score: 14.79
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 412..462
score: 14.75
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 403..464
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 492..552
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 598..656
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 3158..3217
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 3271..3329
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 894..955
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 3023..3085
IPR000716Thyroglobulin type-1SMARTSM00211TY_2coord: 776..822
e-value: 1.8E-13
score: 60.8
coord: 284..331
e-value: 2.2E-15
score: 67.1
coord: 184..233
e-value: 2.3E-10
score: 50.4
IPR000716Thyroglobulin type-1PFAMPF00086Thyroglobulin_1coord: 177..229
e-value: 2.4E-11
score: 43.0
coord: 762..817
e-value: 2.6E-13
score: 49.3
coord: 263..327
e-value: 1.8E-13
score: 49.8
IPR000716Thyroglobulin type-1GENE3D4.10.800.10coord: 752..821
e-value: 2.2E-16
score: 59.0
coord: 164..232
e-value: 5.7E-16
score: 57.7
coord: 261..330
e-value: 8.0E-16
score: 57.2
IPR000716Thyroglobulin type-1PROSITEPS00484THYROGLOBULIN_1_1coord: 775..804
IPR000716Thyroglobulin type-1PROSITEPS00484THYROGLOBULIN_1_1coord: 183..213
IPR000716Thyroglobulin type-1PROSITEPS00484THYROGLOBULIN_1_1coord: 283..312
IPR000716Thyroglobulin type-1PROSITEPS51162THYROGLOBULIN_1_2coord: 164..229
score: 10.542
IPR000716Thyroglobulin type-1PROSITEPS51162THYROGLOBULIN_1_2coord: 752..818
score: 10.588
IPR000716Thyroglobulin type-1PROSITEPS51162THYROGLOBULIN_1_2coord: 265..327
score: 12.112
IPR000716Thyroglobulin type-1SUPERFAMILY57610Thyroglobulin type-1 domaincoord: 158..231
IPR000716Thyroglobulin type-1SUPERFAMILY57610Thyroglobulin type-1 domaincoord: 742..819
IPR000716Thyroglobulin type-1SUPERFAMILY57610Thyroglobulin type-1 domaincoord: 263..329
IPR003582ShKT domainSMARTSM00254ShkT_1coord: 3338..3373
e-value: 7.0E-7
score: 38.9
coord: 829..866
e-value: 2.8E-4
score: 30.2
coord: 331..368
e-value: 1.3E-6
score: 38.0
IPR003582ShKT domainPFAMPF01549ShKcoord: 829..865
e-value: 3.9E-4
score: 20.8
coord: 3338..3372
e-value: 0.027
score: 14.9
coord: 332..367
e-value: 2.9E-7
score: 30.8
IPR003582ShKT domainPROSITEPS51670SHKTcoord: 830..865
score: 7.769
IPR003582ShKT domainPROSITEPS51670SHKTcoord: 332..367
score: 10.693
IPR003582ShKT domainPROSITEPS51670SHKTcoord: 3339..3372
score: 7.822
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 2554..2769
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 662..697
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 2459..2496
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 985..1065
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1166..1506
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 712..750
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 2788..2881
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1526..2314
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 2900..2989
NoneNo IPR availableCDDcd00191TYcoord: 755..818
e-value: 1.49102E-15
score: 74.0373
NoneNo IPR availableCDDcd00109KUcoord: 901..954
e-value: 1.52035E-22
score: 93.8538
NoneNo IPR availableCDDcd00191TYcoord: 167..229
e-value: 2.70591E-12
score: 64.7925
NoneNo IPR availableCDDcd00109KUcoord: 3029..3081
e-value: 2.75919E-20
score: 87.3054
NoneNo IPR availableCDDcd00109KUcoord: 3278..3328
e-value: 4.25322E-17
score: 78.0606
NoneNo IPR availableCDDcd00191TYcoord: 267..327
e-value: 4.82613E-18
score: 81.3561
NoneNo IPR availableCDDcd00109KUcoord: 412..463
e-value: 2.0349E-17
score: 79.2162
NoneNo IPR availableCDDcd00109KUcoord: 494..551
e-value: 1.99165E-14
score: 70.3566
NoneNo IPR availableCDDcd00109KUcoord: 3163..3215
e-value: 1.37892E-18
score: 82.683
NoneNo IPR availableCDDcd00109KUcoord: 605..655
e-value: 1.72245E-22
score: 93.8538
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 931..949
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 3193..3211
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 528..546
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 633..651
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 440..458
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 3059..3077

Blast
[Close]
BLAST of Putative cnidarian restricted protein vs. Swiss-Prot (Human)
Match: TFPI1 (Tissue factor pathway inhibitor OS=Homo sapiens GN=TFPI PE=1 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 5.563e-31
Identity = 81/254 (31.89%), Postives = 121/254 (47.64%), Query Frame = 0 
Query:  407 LYKTSCDMPKVSGNCEGNFQRYYYDQLTNECKLFVYGGCRGNKNNYISQGKCEQECVQEIQPTEAPLSTTPVITFQPKITTDPKDITDPCEMPLQRGTCDSGSVTADQRYYFNKVNGECQVFAFGGCDSNENNFLSKSECENMCIYRKVTTPSINEVTDGLGGPSLKEGCGHAYGCCEDGVTPSLGPDFEGCP-VYE----SYCMMPAATGPCREYLPRYYYNHETGQCELFVYGGCGGNNNRFYTPQECYRDC 655
            L  + C      G C+   +R++++  T +C+ F+YGGC GN+N + S  +C++ C ++        +   +I      TT  ++  D C +    G C  G +T   RY++N    +C+ F +GGC  N NNF +  EC+N+C              DG  G  +       YG   + V  SL P     P ++E    S+C+ PA  G CR    R+YYN   G+C  F Y GCGGN N F + QEC R C
Sbjct:   49 LMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD--------NANRIIK-----TTLQQEKPDFCFLEEDPGIC-RGYIT---RYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC-------------EDGPNGFQVDN-----YGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267

HSP 2 Score: 83.1889 bits (204), Expect = 1.383e-16
Identity = 52/171 (30.41%), Postives = 71/171 (41.52%), Query Frame = 0 
Query: 3165 CEYPPNRGPCRAAISRWYYNHRNKSCEMFTFGGCQPNGNNFDSEDLCYEACQSGDNFIDETLTDTGLSETYETVEALVIPGCPSNSGRYGCCVDGITPAQGPNQQGCPEY-----KSECDMPAVTGGGNDRLIRYYYNPSKKECESFAYSGKGGNRNNFISQQACERRCSE 3330
            C    + G CR  I+R++YN++ K CE F +GGC  N NNF++ + C   C+ G N                                YG  ++ +  +  P     P        S C  PA  G       R+YYN    +C  F YSG GGN NNF S+Q C R C +
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGF--------------------------QVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269
The following BLAST results are available for this feature:
BLAST of Putative cnidarian restricted protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TFPI15.563e-3131.89Tissue factor pathway inhibitor OS=Homo sapiens GN... [more]
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