TCONS_00014208-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00014208-protein
Unique NameTCONS_00014208-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length387

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00014208-protein ID=TCONS_00014208-protein|Name=TCONS_00014208-protein|organism=Clytia hemisphaerica|type=polypeptide|length=387bp
MPQKEDSKSFKIILPPELSKYYEDKNKVLGSGGFAKVILAEHIATGQKVA
IKVMNKNYLKKKDDLHRAYNEIYALKHLSHQHVCQLFEVFECEEFIYLVI
EHCPGGELFDYIVTKKRLEEREARYLFSQILSAVAHFHKHGYAHRDLKPE
NMLLDDDKNIKIIDFGLSAKPENGLTSALRTRAGSVLYASPELISGEPYF
GDKTDIWSLGVVLYALLCGFLPFDHESTVELYKKIKKGEFAKPPWLSPKS
LSLLNGMLETDPKRRITIEKILSHPWMASSSICIPQETKITRNALNYRAV
QLIAAYFKWSLVYAEKKLSAFKYNQLTAIYFILCKSSEEKLSFLCKCWLK
RDHFIGEAMKVQPIKSLTLHWLKEKALLALEKPDECC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007950XLOC_007950Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00014208TCONS_00014208Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR017348PIM1/2/3
IPR008271Ser/Thr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0004674protein serine/threonine kinase activity
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0043066negative regulation of apoptotic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0043066 negative regulation of apoptotic process
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004674 protein serine/threonine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 23..277
e-value: 2.1E-95
score: 333.0
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 25..277
e-value: 7.5E-71
score: 238.5
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 23..277
score: 50.788
NoneNo IPR availableGENE3D1.10.510.10coord: 119..309
e-value: 7.0E-60
score: 201.7
NoneNo IPR availableGENE3D3.30.200.20coord: 18..118
e-value: 3.6E-31
score: 106.8
IPR017348Serine/threonine-protein kinase pim-1/2/3PIRSFPIRSF037993STPK_Pim-1coord: 15..296
e-value: 2.9E-37
score: 126.1
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 142..154
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 29..52
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 26..320

Blast
[Close]
BLAST of TCONS_00014208-protein vs. Swiss-Prot (Human)
Match: MELK (Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3)

HSP 1 Score: 306.99 bits (785), Expect = 8.431e-99
Identity = 144/261 (55.17%), Postives = 194/261 (74.33%), Query Frame = 0 
Query:   17 ELSKYYEDKNKVLGSGGFAKVILAEHIATGQKVAIKVMNKNYLKKKDDLHRAYNEIYALKHLSHQHVCQLFEVFECEEFIYLVIEHCPGGELFDYIVTKKRLEEREARYLFSQILSAVAHFHKHGYAHRDLKPENMLLDDDKNIKIIDFGLSAKPENGLTSALRTRAGSVLYASPELISGEPYFGDKTDIWSLGVVLYALLCGFLPFDHESTVELYKKIKKGEFAKPPWLSPKSLSLLNGMLETDPKRRITIEKILSHPWM 277
            EL KYYE  ++ +G+GGFAKV LA HI TG+ VAIK+M+KN L    DL R   EI ALK+L HQH+CQL+ V E    I++V+E+CPGGELFDYI+++ RL E E R +F QI+SAVA+ H  GYAHRDLKPEN+L D+   +K+IDFGL AKP+      L+T  GS+ YA+PELI G+ Y G + D+WS+G++LY L+CGFLPFD ++ + LYKKI +G++  P WLSP S+ LL  ML+ DPK+RI+++ +L+HPW+
Sbjct:    6 ELLKYYE-LHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS--DLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 263
The following BLAST results are available for this feature:
BLAST of TCONS_00014208-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MELK8.431e-9955.17Maternal embryonic leucine zipper kinase OS=Homo s... [more]
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