TCONS_00012487-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012487-protein
Unique NameTCONS_00012487-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length882

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012487-protein ID=TCONS_00012487-protein|Name=TCONS_00012487-protein|organism=Clytia hemisphaerica|type=polypeptide|length=882bp
MYAVLKGHRLFCYKNSGDGDDDIIQPIPIRGSIIEILSHYPKRRHVFRLI
TSHGNEYLFQSEDSTSMMSWVHTLRDANPDKESLMKTSSQLNQENEQKAN
SKDKKGLSIRRSNFLRSSKKGRSSSNPNPKIPKLPMETAHPAGKTFGIPL
HKCSMSKTQEKVPLIVEHCCTVIEEKADTVGIYRIPGNAATIQSLRSELD
TKDPADIQWDDEKWQEVHNISTLLKAFLRQLDDPIVPSNMYTKFITVNRF
TDQRDRLKSIKHLTRNLPDYHLETLQFLLRHLKLIAEHSEHNKMDLKNLV
TLFGPNIVKSDEVTSLVQDMADQCKIIETLIKQFDWIFNDDAEGGEPIEC
ENGGEIISSGISKALIECLNQNQKSPEQDINENVINNNNNKKSNKFSTLR
NNFSMKLKSSKVTSPKSQKKKSGNISQEEDPESDDETSGCYSQSPPSSGK
VEKRSAKFKTKETRHVGNKLTMIIPSRQTSDNNSGHLATQIGQFTMNSDV
QINFTPGPRSPELSPSTNRLTENTMNHLNQSNKFNQQTSDYDFKPHAKDD
GCDSGVTSPQQMASDDSDSGAHSSRKESLESLSGPSPRIQRRFPPQRQLS
NSGSSNEERSPTLTTKSSATKGVANRDTESKRTNAVANRSIRRAHKSRTM
NNDKRTETDGHARGTKVVKRSDSAVRRRQNYPNSPRSGKRNLKSIIPGDG
NDYEEQLRLMLDGEVDETVYTQTETSEVAQKPDTLEIPNSRAVVLSGAKT
PDSGHNAEWWLSGNQNNYRRFLSAPKDKASAISILSNVIDNSRKRNSKEG
QENELHSPSTSNVSEFSNRVNTHRQRNDEFEKKVTXVIVALIAVVKNRWS
RYQGPAPASNDVFHHNVNSQTAAVVMKSALLL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007023XLOC_007023Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012487TCONS_00012487Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001605PH_dom-spectrin-type
IPR000198RhoGAP_dom
IPR011993PH_dom-like
IPR001849PH_domain
IPR008936Rho_GTPase_activation_prot
Vocabulary: Molecular Function
TermDefinition
GO:0005543phospholipid binding
GO:0005515protein binding
Vocabulary: Biological Process
TermDefinition
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007165 signal transduction
molecular_function GO:0005543 phospholipid binding
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 813..833
NoneNo IPR availableCOILSCoilCoilcoord: 84..104
NoneNo IPR availableGENE3D1.10.555.10coord: 78..348
e-value: 3.8E-63
score: 212.6
IPR001605Pleckstrin homology domain, spectrin-typePRINTSPR00683SPECTRINPHcoord: 54..72
score: 45.03
coord: 34..51
score: 38.89
IPR000198Rho GTPase-activating protein domainSMARTSM00324RhoGAP_3coord: 160..335
e-value: 1.3E-46
score: 170.8
IPR000198Rho GTPase-activating protein domainPFAMPF00620RhoGAPcoord: 163..311
e-value: 5.7E-43
score: 146.2
IPR000198Rho GTPase-activating protein domainPROSITEPS50238RHOGAPcoord: 148..338
score: 41.439
IPR011993PH domain-likeGENE3D2.30.29.30coord: 1..77
e-value: 1.3E-15
score: 56.9
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 2..78
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 2..77
e-value: 4.1E-9
score: 36.8
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 1..79
score: 9.942
IPR008936Rho GTPase activation proteinSUPERFAMILY48350GTPase activation domain, GAPcoord: 145..338

Blast
BLAST of TCONS_00012487-protein vs. Swiss-Prot (Human)
Match: RHG23 (Rho GTPase-activating protein 23 OS=Homo sapiens GN=ARHGAP23 PE=1 SV=2)

HSP 1 Score: 246.899 bits (629), Expect = 6.041e-68
Identity = 132/352 (37.50%), Postives = 208/352 (59.09%), Query Frame = 0
Query:   26 PIPIRGSIIEILSHYPKRRHVFRLITSHGNEYLFQSEDSTSMMSWVHTLRD------ANPDKESLMKTSSQLN------QENEQKANS--KDKKGLSIRRSNFLR-SSKKG-------RSSSNPNPKIPKLPM------ETAHPAGKTFGIPLHKCSMSKTQEKVPLIVEHCCTVIEEKA-DTVGIYRIPGNAATIQSLRSELDTKDPADIQWDDEKWQEVHNISTLLKAFLRQLDDPIVPSNMYTKFITVNRFTDQRDRLKSIKHLTRNLPDYHLETLQFLLRHLKLIAEHSEHNKMDLKNLVTLFGPNIVKS--DEVTSLVQDMADQCKIIETLIKQFDWIFNDDAEGGE 346
            P+ I   +++I     KRRHVFRL T+   EYLFQ+ED   M+ W+  +R+       +P   +    S +LN        +  KA+S  K  +GL   +S FL+ S+ +G         S + +   PK P       +    A + FG+ L +C  +   ++VPLIV  CC ++E +  ++ GIYR+PGN A + SL+ +L+ + P DI   DE+WQ+++ IS+LLK+F R+L +P+   + Y  FI  NR  D R+R+++++ L R+LP ++ ETL+FL+ HLK IA+HSE NKM+ +NL  +FGP +V++  D +T +V  M D+ KI+ETLI+  DW F+D+ + GE
Sbjct:  755 PVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLN-RGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDEEDKGE 1105          
The following BLAST results are available for this feature:
BLAST of TCONS_00012487-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
RHG236.041e-6837.50Rho GTPase-activating protein 23 OS=Homo sapiens G... [more]
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