TCONS_00012385-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012385-protein
Unique NameTCONS_00012385-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length326

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012385-protein ID=TCONS_00012385-protein|Name=TCONS_00012385-protein|organism=Clytia hemisphaerica|type=polypeptide|length=326bp
MKLIVALCLLGLACAYTIEHKEVIADSSWHLFKGSHSKYYADINEEKVRY
TIWQDNLRRIEEHNSQNKDVVLKMNHFGDLTNTEFRYLMNGYRHQNMTGS
TYLAPSHATVPDTVDWRQQGYVTPVKNQGQCGSCWAFSTTGSLEGQHFKK
TGKLVSLSEQNLVDCSSKQGNMGCNGGLMDQAFTYIKKNGGIDTEGSYPY
HAKNEQCHYKSADSGATVTGFTDIPQGDEDALKSAVATVGPVSVAIDASH
FSFQFYHTGVYNEKSCSSTQLDHGVLAVGYGTYQGKDYWLVKNSWGPGWG
LKGYIRMSRNKKNQCGIASSASYPLV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006965XLOC_006965Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012385TCONS_00012385Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000668Peptidase_C1A_C
IPR013201Prot_inhib_I29
IPR025660Pept_his_AS
IPR000169Pept_cys_AS
IPR025661Pept_asp_AS
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
Vocabulary: Molecular Function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0008234 cysteine-type peptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000668Peptidase C1A, papain C-terminalPRINTSPR00705PAPAINcoord: 288..294
score: 75.76
coord: 128..143
score: 65.72
coord: 273..283
score: 59.77
IPR000668Peptidase C1A, papain C-terminalSMARTSM00645pept_c1coord: 110..325
e-value: 1.1E-128
score: 443.5
IPR000668Peptidase C1A, papain C-terminalPFAMPF00112Peptidase_C1coord: 110..324
e-value: 1.9E-89
score: 299.4
IPR013201Cathepsin propeptide inhibitor domain (I29)SMARTSM00848Inhibitor_I29_2coord: 29..85
e-value: 6.8E-19
score: 78.8
IPR013201Cathepsin propeptide inhibitor domain (I29)PFAMPF08246Inhibitor_I29coord: 31..85
e-value: 6.7E-12
score: 45.6
NoneNo IPR availableGENE3D3.90.70.10coord: 23..326
e-value: 2.6E-119
score: 398.0
NoneNo IPR availableCDDcd02248Peptidase_C1Acoord: 111..324
e-value: 3.58461E-123
score: 354.237
NoneNo IPR availableSUPERFAMILY54001Cysteine proteinasescoord: 25..325
IPR025660Cysteine peptidase, histidine active sitePROSITEPS00639THIOL_PROTEASE_HIScoord: 271..281
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 128..139
IPR025661Cysteine peptidase, asparagine active sitePROSITEPS00640THIOL_PROTEASE_ASNcoord: 288..307

Blast
BLAST of TCONS_00012385-protein vs. Swiss-Prot (Human)
Match: CATL2 (Cathepsin L2 OS=Homo sapiens GN=CTSV PE=1 SV=2)

HSP 1 Score: 364.385 bits (934), Expect = 3.284e-126
Identity = 182/336 (54.17%), Postives = 233/336 (69.35%), Query Frame = 0
Query:    1 MKLIVALCLLGLACAYTIEHKEVIADSSWHLFKGSHSKYYADINEEKVRYTIWQDNLRRIEEHN---SQNK-DVVLKMNHFGDLTNTEFRYLMNGYRHQNM-TGSTYLAPSHATVPDTVDWRQQGYVTPVKNQGQCGSCWAFSTTGSLEGQHFKKTGKLVSLSEQNLVDCSSKQGNMGCNGGLMDQAFTYIKKNGGIDTEGSYPYHAKNEQCHYKSADSGATVTGFTDIPQGDEDALKSAVATVGPVSVAIDASHFSFQFYHTGVYNEKSCSSTQLDHGVLAVGYGTYQGKD-----YWLVKNSWGPGWGLKGYIRMSRNKKNQCGIASSASYPLV 326
            + L++A   LG+A A  +   +   D+ W+ +K +H + Y   NEE  R  +W+ N++ IE HN   SQ K    + MN FGD+TN EFR +M  +R+Q    G  +  P    +P +VDWR++GYVTPVKNQ QCGSCWAFS TG+LEGQ F+KTGKLVSLSEQNLVDCS  QGN GCNGG M +AF Y+K+NGG+D+E SYPY A +E C Y+  +S A  TGFT +  G E AL  AVATVGP+SVA+DA H SFQFY +G+Y E  CSS  LDHGVL VGYG ++G +     YWLVKNSWGP WG  GY++++++K N CGIA++ASYP V
Sbjct:    3 LSLVLAAFCLGIASA--VPKFDQNLDTKWYQWKATHRRLYG-ANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYG-FEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334          
The following BLAST results are available for this feature:
BLAST of TCONS_00012385-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CATL23.284e-12654.17Cathepsin L2 OS=Homo sapiens GN=CTSV PE=1 SV=2[more]
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