TCONS_00008326-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00008326-protein
Unique NameTCONS_00008326-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1128

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00008326-protein ID=TCONS_00008326-protein|Name=TCONS_00008326-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1128bp
METKITWEQLHISLPDTLYIGIKISGQTLLIQLDRKNDLLTDDFSSEDVI
DIQAKEGNGLERRLVDSFHLHCYYAGFVFGISDSKVTISTCDGLRGYINL
DNEAYQIQPMRAQDGGFAHLVYRSDAKKAEHGRSMECVTGRFERKFEDGQ
PDTTFDENMNIRHFTKESNHHQQVQQINRTTQQKRTRRSTFSQQVIATVE
VFVVADKDMIQFHGNDTIEDYVLTMMNMVSDMYKEPSLGAIVNIVVTKLL
VLDTDEVKISSNGDKTLASFCEWQFLQNLRNPNSNQKFDVALLLTRKDLC
LRSDVPCGTIGLAYIGGMCSSNRKCAVIEDIGLNTAYTIAHELGHTLGMQ
HDGLDNNCATQSNGRSHMMASHWPAVSAKPMKWSKCSANKLQSYLSSYKS
FCIQSKAPVFNIEYEHRRKFPGELYDADTQCQQQFGKFSRHCKYFKRTGM
ATKMCQKLWCEVEGEQFCMSKLDAAAKGTECNPAKWCMYGKCVPNTEIPH
AIHGGWSKWTGWSRCTRHCGIGVQQRERFCDNPSPRNGGQPCPGERIEHK
TCNTRPCMASSRDFRRKQCSQINNSTHTFVPVHSSKEPCSLHCRPESNNA
YYSIRVRSQVVDGTPCYEGSSDICVNGQCRQIGCDLKLNSKLFTDVCGVC
GGKADTCRMIEGKFSQPLGEGYVKAVDIPRGARNVLVQEVRPCPSFLALS
GPGSYNINGNYTIKLPGTYDFNGTSVTYRRRGTQETYLVEGPLKTTMHFK
VLFQGYNFGIKYRYVMPIDKEEIEKNSQKKKDLQLKKKQAKRFGWMQGQW
KKCSVQCGGGIMRREKARCLHFEGTKATFVENGKCVHAKSPVDEVKACNE
QKCQKAWYKGDWSYCSRPCGNGRKTRKVVCKEQKQNGGWKIIDPNECNPA
TKPISVSACIIRSCFLKWEASKWGKCQGKCGKTGFMEREVTCSRPNGCNP
KTKPIVRRRCRMTKCKYGWTVQPWGPCSKSCGKGAQTRLIDCRSKKTFKI
APTKLCTDSKQPRVSRACLTKCKKTPSRKIRYRGRRPSLNQRPLQSPASP
SKNKVNIFKNLLNISVPINRTKQCKDRLLSWSCKMFILVYSAAGGRSYCY
TAKAQSQCCATCRIERNKRRRRRKRFIA
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_004673XLOC_004673Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00008326TCONS_00008326Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR013273Peptidase_M12B_ADAM-TS
IPR000884TSP1_rpt
IPR002870Peptidase_M12B_N
IPR001590Peptidase_M12B
IPR010294ADAM_spacer1
IPR024079MetalloPept_cat_dom
Vocabulary: Molecular Function
TermDefinition
GO:0008270zinc ion binding
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013273Peptidase M12B, ADAM-TSPRINTSPR01857ADAMTSFAMILYcoord: 512..530
score: 50.59
coord: 618..637
score: 43.67
coord: 638..657
score: 48.67
NoneNo IPR availablePRINTSPR01705TSP1REPEATcoord: 522..533
score: 46.35
coord: 504..517
score: 46.3
coord: 541..552
score: 35.27
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1032..1052
NoneNo IPR availableCDDcd04273ZnMc_ADAMTS_likecoord: 198..402
e-value: 2.34226E-82
score: 266.412
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 198..404
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 857..903
e-value: 0.15
score: 16.6
coord: 968..1023
e-value: 0.25
score: 14.6
coord: 506..558
e-value: 2.1E-12
score: 57.2
coord: 917..966
e-value: 3.1
score: 5.0
coord: 795..854
e-value: 0.063
score: 20.0
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 972..1018
e-value: 8.5E-4
score: 19.4
coord: 860..887
e-value: 5.3E-5
score: 23.3
coord: 507..557
e-value: 1.3E-9
score: 38.0
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 502..557
e-value: 2.2E-17
score: 62.6
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 854..914
e-value: 3.9E-8
score: 33.1
coord: 790..853
e-value: 5.6E-7
score: 29.4
coord: 916..965
e-value: 1.0E-5
score: 25.4
coord: 966..1022
e-value: 1.1E-9
score: 38.1
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 914..966
score: 9.561
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 503..558
score: 13.74
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 969..1023
score: 8.641
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 853..913
score: 8.575
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 501..557
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 795..853
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 969..1020
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 857..914
IPR002870Peptidase M12B, propeptidePFAMPF01562Pep_M12B_propepcoord: 15..122
e-value: 1.7E-18
score: 67.1
IPR001590Peptidase M12B, ADAM/reprolysinPFAMPF01421Reprolysincoord: 199..405
e-value: 1.2E-27
score: 97.0
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 197..407
score: 24.501
IPR010294ADAM-TS Spacer 1PFAMPF05986ADAM_spacer1coord: 659..767
e-value: 6.3E-23
score: 80.9
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 194..429
e-value: 1.8E-69
score: 233.4

Blast
BLAST of TCONS_00008326-protein vs. Swiss-Prot (Human)
Match: ATS17 (A disintegrin and metalloproteinase with thrombospondin motifs 17 OS=Homo sapiens GN=ADAMTS17 PE=2 SV=2)

HSP 1 Score: 588.956 bits (1517), Expect = 0.000e+0
Identity = 359/1012 (35.47%), Postives = 485/1012 (47.92%), Query Frame = 0
Query:   17 TLYIGIKISGQTLLIQLDRKNDLLTDDFSSEDVIDIQAKEGNGLERRLVDSFHLHCYYAGFVFGISDSKVTISTC---DGLRGYINLDNEAYQIQPMRAQDGGFA---HLVYR----SDAKKAEHGRSME-CVTGRFERKFEDGQPDTTFDENMNIRHFTKESNHHQQVQQINRTTQQKRTRRSTFSQQVIATVEVFVVADKDMIQFHGNDTIEDYVLTMMNMVSDMYKEPSLGAIVNIVVTKLLVLDTDEVKIS--SNGDKTLASFCEWQ--------FLQNLRNPNSNQK---FDVALLLTRKDLCLRSDVPCGTIGLAYIGGMCSSNRKCAVIEDIGLNTAYTIAHELGHTLGMQHDGLDNNCATQSNGRSHMMASHW-PAVSAKPMKWSKCSANKLQSYLSSYKSFCIQSKAPVFNIEYEHRRKFPGELYDADTQCQQQFGKFSRHCKYFKRTGMATKMCQKLWCEVEGEQFCMSKLDAAAKGTECNPAKWCMYGKCVPNTEIPHAIHGGWSKWTGWSRCTRHCGIGVQQRERFCDNPSPRNGGQPCPGERIEHKTCNTRPCMASSRDFRRKQCSQINNST----HTFVPVHSSKEPCSLHCRPESNNAYYSIRVRSQVVDGTPCYEGSSDICVNGQCRQIGCDLKLNSKLFTDVCGVCGGKADTCRMIEGKFSQPLGEGYVKAVDIPRGARNVLVQEVRPCPSFLALSGPGSYNINGNYTIKLPGTYDFNGTSVTYRRRGTQETYLVEGPLKTTMHFKV-LFQGYNFGIKYRYVMPIDKEEIEKNSQKKKDLQLKKKQAKRFGWMQGQWKKCSVQCGGGIMRREKARCLHFEGTKATFVENGKCVHAKSPVDEVKACNEQKCQKAWYKGDWSYCSRPCGNGRKTRKVVCKEQKQNGGWKIIDPNECNPATKPISVSACIIRSCFLKWEASKWGKCQGKCGKTGFMEREVTCSRPNG-CNPKTKPIVRRRCRMTKCKYGWTVQPWGPCSKSCGKGAQTRLIDCRSKKT 997
             L + +   G+ L +QL R    L+  F  E+          G  RR      L C+Y+G V G   S V++S C    GL G I L  E   IQP+    G F+   HL+ R    + +  AE  R  + C     ++K   G+P   + E  N    T E                              TVE  VVAD DM+Q+HG +  + ++LT+MNMV +M++  SLG  +NI VTKL++L     K+S   +G+++L SFC WQ        +L N + P         D A+ +TR D C+  D PC T+G+AY+GG+CS+ RKC + ED GLN A+TIAHELGH LGM HD   ++CA    GRSH+M+  W    +   + WS CS + L+++L S  S C+    P          K PG  Y A+ QCQ  FG  +  C+      M   MC  LWC VEG+  C +KLD    GTEC   KWC  G+CV  T IP  + G WS W  WS C+R CG G + R+R CDNP P  GG  CPG  +EH  C   PC      FR +QC   +  +         V    +PC L+C P    +   + V  +V+DGTPC    +D+CV+G+C++IGCD  + S    D CGVC G   TC +++G FS   G                            AL   G  +IN ++ I+LPG +   GT+V Y RRG  E    +GP K  +H  V LF   ++GI Y Y +P+       N   +   + +K Q   F W    W+ CSVQCGGG  RR    C        T V +  C  A  P  +V+ CN   CQ  W  G WS CS  C  G + R+V C  Q QNG      P  C P  +P +V +C  + C   WEAS+W +C   CGK G  +R V C+   G C+  T+P     C      Y W    W  CS +CGKG Q+R++ C  K T
Sbjct:   80 ALLLHLPAFGRDLYLQLRRDLRFLSRGFEVEEA---------GAARRRGRPAEL-CFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLGQEQVLIQPLNNSQGPFSGREHLIRRKWSLTPSPSAEAQRPEQLCKVLTEKKKPTWGRPSRDWRERRNAIRLTSEH-----------------------------TVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHQSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDPPLVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCA----GRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLVTDPRSQHTVRLPHKLPGMHYSANEQCQILFGMNATFCR-----NMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVDDKPCELYCSPLGKES--PLLVADRVLDGTPCGPYETDLCVHGKCQKIGCDGIIGSAAKEDRCGVCSGDGKTCHLVKGDFSHARG---------------------------TALKDSGKGSINSDWKIELPGEFQIAGTTVRYVRRGLWEKISAKGPTKLPLHLMVLLFHDQDYGIHYEYTVPV-------NRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGG-ERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNLHPCQSRWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYC-PGPRPAAVQSCEGQDCLSIWEASEWSQCSASCGK-GVWKRTVACTNSQGKCDASTRPRAEEACEDYSGCYEWKTGDWSTCSSTCGKGLQSRVVQCMHKVT 1004          
The following BLAST results are available for this feature:
BLAST of TCONS_00008326-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ATS170.000e+035.47A disintegrin and metalloproteinase with thrombosp... [more]
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