TCONS_00006536-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00006536-protein
Unique NameTCONS_00006536-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length245

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00006536-protein ID=TCONS_00006536-protein|Name=TCONS_00006536-protein|organism=Clytia hemisphaerica|type=polypeptide|length=245bp
MAESIENNKPKMLERQISYSDKESLDTGKRHVVKTEWDVSIGGMEKKRRI
DKESDEFDKRITQMSGAVKTILENVGEDPNREGLLDTPERYAKAMLFFTK
GYNLSLSEVLNDAVFNENHDELVIVKDINVFSMCEHHLVPFYGKAHVGYL
PNKKVLGISKVARIVDMFSRRLQVQERLTKQIATALNEAVQPTGVGVIVD
CCHMCMVMRGVQKPGASTVTSCMLGTFRDDPKTREEFLVLTRNYR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003695XLOC_003695Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00006536TCONS_00006536Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001474GTP_CycHdrlase_I
IPR020602GTP_CycHdrlase_I_dom
IPR018234GTP_CycHdrlase_I_CS
Vocabulary: Cellular Component
TermDefinition
GO:0005737cytoplasm
Vocabulary: Molecular Function
TermDefinition
GO:0003934GTP cyclohydrolase I activity
Vocabulary: Biological Process
TermDefinition
GO:0046654tetrahydrofolate biosynthetic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0046654 tetrahydrofolate biosynthetic process
cellular_component GO:0005737 cytoplasm
molecular_function GO:0003934 GTP cyclohydrolase I activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D1.10.286.10coord: 31..106
e-value: 2.8E-20
score: 71.7
NoneNo IPR availableGENE3D3.30.1130.10coord: 112..244
e-value: 5.0E-66
score: 219.7
NoneNo IPR availableCDDcd00642GTP_cyclohydro1coord: 60..242
e-value: 1.18553E-111
score: 320.482
NoneNo IPR availableSUPERFAMILY55620Tetrahydrobiopterin biosynthesis enzymes-likecoord: 43..242
IPR001474GTP cyclohydrolase ITIGRFAMTIGR00063TIGR00063coord: 64..241
e-value: 9.0E-82
score: 270.9
IPR001474GTP cyclohydrolase IHAMAPMF_00223FolEcoord: 60..242
score: 38.65
IPR020602GTP cyclohydrolase I domainPFAMPF01227GTP_cyclohydroIcoord: 66..240
e-value: 6.0E-77
score: 257.0
IPR018234GTP cyclohydrolase I, conserved sitePROSITEPS00859GTP_CYCLOHYDROL_1_1coord: 121..137
IPR018234GTP cyclohydrolase I, conserved sitePROSITEPS00860GTP_CYCLOHYDROL_1_2coord: 169..179

Blast
BLAST of TCONS_00006536-protein vs. Swiss-Prot (Human)
Match: GCH1 (GTP cyclohydrolase 1 OS=Homo sapiens GN=GCH1 PE=1 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 3.177e-94
Identity = 127/201 (63.18%), Postives = 164/201 (81.59%), Query Frame = 0
Query:   43 GMEKKRRIDKESDEFDKRITQMSGAVKTILENVGEDPNREGLLDTPERYAKAMLFFTKGYNLSLSEVLNDAVFNENHDELVIVKDINVFSMCEHHLVPFYGKAHVGYLPNKKVLGISKVARIVDMFSRRLQVQERLTKQIATALNEAVQPTGVGVIVDCCHMCMVMRGVQKPGASTVTSCMLGTFRDDPKTREEFLVLTRN 243
            G + +R   +E +E +  +  ++ A  +IL ++GE+P R+GLL TP R A AM FFTKGY  ++S+VLNDA+F+E+HDE+VIVKDI++FSMCEHHLVPF GK H+GYLPNK+VLG+SK+ARIV+++SRRLQVQERLTKQIA A+ EA++P GVGV+V+  HMCMVMRGVQK  + TVTS MLG FR+DPKTREEFL L R+
Sbjct:   52 GWKGERPRSEEDNELN--LPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS 250          
The following BLAST results are available for this feature:
BLAST of TCONS_00006536-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GCH13.177e-9463.18GTP cyclohydrolase 1 OS=Homo sapiens GN=GCH1 PE=1 ... [more]
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