TCONS_00005911-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00005911-protein
Unique Name	TCONS_00005911-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1372

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00005911-protein ID=TCONS_00005911-protein|Name=TCONS_00005911-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1372bp
ATVFASPTPPQTSTEEGTEVRVKKKSIISIKGRKSSQAVMMEEPNKPSPK
ISQSANGIHNSNNGTIENKTKEDNRIVENRKKETIQQQNGKNTCPQQVDE
NLKNLQNGNTDNSKVSNGHIEGDVPGSQNGNPPIAINPPSRDSSPNTKSQ
NGDSHNIKEEGDNLPKDSLKAPPNQLLKSNLKQSEPKNHHGSSVTTKSKT
VTICPAENHKDSKDGLTENNNGEIKYEKEKKVTILENGGPKKPRDRGLPR
KISMTTENMCRLKNMTTNNETIDTLHISAERQHCSGTRCLGSVVQPSGGL
GTEMLAPGELRSQDELLRQAKDFISQYYKSLKRENIEEEMEERWERVKKE
IELRGTYDLDEKELVFGARLAWRNAARCIGRIQWKKLQVFDFRHVTTAKE
MFDCILQHLQFATNKGKIRSTISIFPHKTEDMKEFRVWNSQIIRYAGYKK
IDGTIVGDPASVEFTEIAQNLGWKGAGTQFDVLPLILQATGRKPEWFEIP
KEYVMEVQIKHPNYPKLDELGLKWYAVPAVSNIMLDCGGLQFTACPFNGW
YMATEVGARNFTDTNRYNLLKQVAQKMGLNTINNSSMWKDRVQLELTFAT
LNSYTEAGVTIVDHHTASESFMKHMKDEEKVRGGCPADWVWIVPPISGSV
TPVFHQEMLNYKLYPSYEYLEDAWKYLRVERPSPLKKRRTFKDVVKIVEL
SNSLFGGILKRRSKVSILYATETGKSKAFANLLNEVFLHGFDSKVYCMQD
YRVTDIENEQCVLFVASTFGNGEPPDNGQDFVKGLHQMIYPTESMKKYRS
FSNLHQGLNEIPENQKGLLCNLRYSVFGLGSRAYPKFCEFGHLLDNSFAK
LGGEQIYPMGEGDELNGQEESFKDWARACFKAACDVFVIKDAKLPASIMD
NPKEWKDGCFRIKKHDKKTERTSICDELRVMHGRKVFPCPIIDVQNLQTK
HSDRVTNLVQISSEGEEGMMYQPGDHLYIYPENDSKRVDKLLKRIRCETD
MDELVMVEQTSRNDIWDAIDKVPLPNTLRRIFTNYLDIESPPSRKLLGFF
ALCAKDEDEKTKLNDLATVIETYDDWRLQDYPSVLEVLNQFKSIDVDVTL
LIDQLPLQKARPYSISSSPKMHPNQIHVTVAFVSYKVKDNVTHLGVCSSY
LNNRRKGDIVPCYVKRAYSFYLPEDKSAPIMLVGPGTGIAPFRSFWQENI
CENRENEIILYFGCRHPLKDNIYKQEMNEALAKKGLTKLHVAYSRQEFKP
KVYVQDLLRQNAEEVCNFLVGESSHFYVCGDVTMASDVFQCLLDILQKHS
AFSQSEAEALIADMKKAGRYHEDIFGVTLKVREVTTRVRSAVKRTRPTSQ
IITSDIITSPPPPSSSLHHELR

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_003367	XLOC_003367	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00005911	TCONS_00005911	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001094	Flavdoxin-like
IPR001709	Flavoprot_Pyr_Nucl_cyt_Rdtase
IPR003097	FAD-binding_1
IPR012144	NOS_euk
IPR001433	OxRdtase_FAD/NAD-bd
IPR004030	NOS_N
IPR008254	Flavodoxin/NO_synth
IPR029039	Flavoprotein-like_dom
IPR017927	Fd_Rdtase_FAD-bd
IPR017938	Riboflavin_synthase-like_b-brl

Vocabulary: **Biological Process**
Term	Definition
GO:0055114	oxidation-reduction process
GO:0006809	nitric oxide biosynthetic process

Vocabulary: **Molecular Function**
Term	Definition
GO:0010181	FMN binding
GO:0016491	oxidoreductase activity
GO:0005506	iron ion binding
GO:0050660	flavin adenine dinucleotide binding
GO:0005516	calmodulin binding
GO:0050661	NADP binding
GO:0020037	heme binding
GO:0004517	nitric-oxide synthase activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006809	nitric oxide biosynthetic process
biological_process	GO:0055114	oxidation-reduction process
molecular_function	GO:0005516	calmodulin binding
molecular_function	GO:0050660	flavin adenine dinucleotide binding
molecular_function	GO:0010181	FMN binding
molecular_function	GO:0020037	heme binding
molecular_function	GO:0005506	iron ion binding
molecular_function	GO:0050661	NADP binding
molecular_function	GO:0004517	nitric-oxide synthase activity
molecular_function	GO:0016491	oxidoreductase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001094	Flavodoxin-like	PRINTS	PR00369	FLAVODOXIN	coord: 716..729 score: 42.63 coord: 845..864 score: 36.88 coord: 763..774 score: 55.21 coord: 821..831 score: 59.94
IPR001709	Flavoprotein pyridine nucleotide cytochrome reductase	PRINTS	PR00371	FPNCR	coord: 1181..1200 score: 52.07 coord: 1251..1267 score: 31.03 coord: 1206..1215 score: 38.74 coord: 1219..1230 score: 30.36 coord: 1275..1283 score: 49.81 coord: 971..981 score: 43.78 coord: 1145..1154 score: 41.26 coord: 1111..1118 score: 67.53
IPR003097	FAD-binding, type 1	PFAM	PF00667	FAD_binding_1	coord: 931..1150 e-value: 3.0E-54 score: 183.8
None	No IPR available	GENE3D	2.40.30.10		coord: 919..1164 e-value: 1.6E-45 score: 155.0
None	No IPR available	GENE3D	3.40.50.80		coord: 1167..1324 e-value: 1.5E-35 score: 121.9
None	No IPR available	GENE3D	3.90.1230.10		coord: 506..616 e-value: 3.9E-49 score: 164.9
None	No IPR available	GENE3D	3.90.340.10		coord: 273..438 e-value: 8.2E-56 score: 187.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..174
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1351..1372
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 179..198
None	No IPR available	SUPERFAMILY	52343	Ferredoxin reductase-like, C-terminal NADP-linked domain	coord: 1169..1326
IPR012144	Nitric-oxide synthase, eukaryote	PIRSF	PIRSF000333	INOS	coord: 31..1351 e-value: 0.0 score: 1505.1
IPR001433	Oxidoreductase FAD/NAD(P)-binding	PFAM	PF00175	NAD_binding_1	coord: 1182..1288 e-value: 8.1E-18 score: 65.0
IPR004030	Nitric oxide synthase, N-terminal	PFAM	PF02898	NO_synthase	coord: 313..675 e-value: 1.1E-175 score: 583.8
IPR004030	Nitric oxide synthase, N-terminal	PROSITE	PS60001	NOS	coord: 377..384
IPR004030	Nitric oxide synthase, N-terminal	SUPERFAMILY	56512	Nitric oxide (NO) synthase oxygenase domain	coord: 260..677
IPR008254	Flavodoxin/nitric oxide synthase	PFAM	PF00258	Flavodoxin_1	coord: 717..875 e-value: 8.5E-40 score: 136.2
IPR008254	Flavodoxin/nitric oxide synthase	PROSITE	PS50902	FLAVODOXIN_LIKE	coord: 715..880 score: 28.566
IPR029039	Flavoprotein-like domain	GENE3D	3.40.50.360		coord: 673..897 e-value: 2.7E-50 score: 170.0
IPR029039	Flavoprotein-like domain	SUPERFAMILY	52218	Flavoproteins	coord: 712..888
IPR017927	Ferredoxin reductase-type FAD-binding domain	PROSITE	PS51384	FAD_FR	coord: 934..1173 score: 14.542
IPR017938	Riboflavin synthase-like beta-barrel	SUPERFAMILY	63380	Riboflavin synthase domain-like	coord: 923..1166

Blast

[Close]

BLAST of TCONS_00005911-protein vs. Swiss-Prot (Human)
Match: NOS1 (Nitric oxide synthase, brain OS=Homo sapiens GN=NOS1 PE=1 SV=2)

HSP 1 Score: 998.038 bits (2579), Expect = 0.000e+0
Identity = 526/1151 (45.70%), Postives = 733/1151 (63.68%), Query Frame = 0

Query:  227 EKEKKVTILENGGPKKPRDRGLPRKISMTTENMCRLKNMTTNNETIDTLHI-SAERQHCSGTRCLGSVVQPSGGLGTEMLAPGELRSQDELLRQAKDFISQYYKSLKRENIEEEMEERWERVKKEIELRGTYDLDEKELVFGARLAWRNAARCIGRIQWKKLQVFDFRHVTTAKEMFDCILQHLQFATNKGKIRSTISIFPHKTEDMKEFRVWNSQIIRYAGYKKIDGTIVGDPASVEFTEIAQNLGWKGAGTQFDVLPLILQATGRKPEWFEIPKEYVMEVQIKHPNYPKLDELGLKWYAVPAVSNIMLDCGGLQFTACPFNGWYMATEVGARNFTDTNRYNLLKQVAQKMGLNTINNSSMWKDRVQLELTFATLNSYTEAGVTIVDHHTASESFMKHMKDEEKVRGGCPADWVWIVPPISGSVTPVFHQEMLNYKLYPSYEYLEDAWK--YLRVERPSPLKKRRT-FKDVVKIVELSNSLFGGILKRRSKVSILYATETGKSKAFANLLNEVFLHGFDSKVYCMQDYRVTDIENEQCVLFVASTFGNGEPPDNGQDFVKGLHQMIYPTESMKKYRSFSNLHQGLN-------------EIPEN--QKGLLCNLRYSVFGLGSRAYPKFCEFGHLLDNSFAKLGGEQIYPMGEGDELNGQEESFKDWARACFKAACDVFVIKD----AKLPASIMDNPKEWKDGCFRIKKHDKKTERTSICDELRVMHGRKVFPCPIIDVQNLQTKHSDRVTNLVQISSEGEEGMMYQPGDHLYIYPENDSKRVDKLLKRIRCETDMDELVMVE-----QTSRNDIWDAIDKVPLPN-TLRRIFTNYLDIESPPSRKLLGFFALCAKDEDEKTKLNDLATVIETYDDWRLQDYPSVLEVLNQFKSIDVDVTLLIDQLPLQKARPYSISSSPKMHPNQIHVTVAFVSYKVKD--NVTHLGVCSSYLNNRRKGDIVPCYVKRAYSFYLPEDKSAPIMLVGPGTGIAPFRSFWQENICENREN-----EIILYFGCRHPLKDNIYKQEMNEALAKKGLTKLHVAYSRQEFKPKVYVQDLLR-QNAEEVCNFLVGESSHFYVCGDVTMASDVFQCLLDILQKHSAFSQSEAEALIADMKKAGRYHEDIFGVTLKVREVTTRVRS 1340
            EKE+  T     G + P   G P K         ++KN  T     DTLH+ S     C+   C+GS++ PS         P ++R++ +L   AK+FI QYY S+KR   +  ME R E V KEI+   TY L + EL++GA+ AWRNA+RC+GRIQW KLQVFD R  TTA  MF+ I  H+++ATNKG +RS I+IFP +T+   +FRVWNSQ+IRYAGYK+ DG+ +GDPA+V+FTEI    GWK    +FDVLPL+LQA G  PE F+IP E V+EV I+HP +    +LGLKWY +PAVSN++L+ GGL+F+ACPF+GWYM TE+G R++ D +RYN+L++VA+KM L+    SS+WKD+  +E+  A L S+    VTIVDHH+A+ESF+KHM++E + RGGCPADWVWIVPP+SGS+TPVFHQEMLNY+L PS+EY  D W     +    +P K+R   FK + + V+ S  L G  + +R K +ILYATETGKS+A+A  L E+F H FD+KV  M++Y +  +E+E  VL V STFGNG+PP+NG+ F   L +M +P    ++ +S+      ++             ++ +N    G L N+R+SVFGLGSRAYP FC FGH +D    +LGGE+I  M EGDEL GQEE+F+ WA+  FKAACDVF + D     K   S++ N + WK   FR+    +  E T     L  +H ++V    ++  QNLQ+  S R T  V++ + G + + YQPGDHL ++P N    V+ L++R+     ++++V VE      T+   I +  D++ LP  T+ + F  YLDI +PP+   L  FA  A  E EK +L  L+  ++ Y++W+    P+++EVL +F SI +  TLL+ QL L + R YSISSSP M+P+++H+TVA VSY+ +D     H GVCSS+LN  +  ++VPC+V+ A SF+LP +   P +LVGPGTGIAPFRSFWQ+   + +        ++L FGCR    D+IY++E  +A  K    +L+ AYSR+  KPK YVQD+L+ Q AE V   L  +  H YVCGDVTMA+DV + +  I+ +    S  +A   I+ M+   RYHEDIFGVTL+  EVT R+RS
Sbjct:  281 EKEQPPT----SGKQSPTKNGSPSKCP----RFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPS----QHARRPEDVRTKGQLFPLAKEFIDQYYSSIKRFGSKAHME-RLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELTQ---GLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRS 1415

The following BLAST results are available for this feature:

BLAST of TCONS_00005911-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00005911-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
NOS1	0.000e+0	45.70	Nitric oxide synthase, brain OS=Homo sapiens GN=NO...	[more]

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TCONS_00005911-protein (polypeptide) - C. hemisphaerica