TCONS_00005001-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00005001-protein
Unique Name	TCONS_00005001-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	464

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00005001-protein ID=TCONS_00005001-protein|Name=TCONS_00005001-protein|organism=Clytia hemisphaerica|type=polypeptide|length=464bp
MLHNNQVLLVFMGLCFFWFVNCNRPKLNSTTKETKEEKIDREEIFLAQNF
DHLLNQYDKNIRPNYTGKPIVVTVDLTVMAFGAINERGMTFATDLYFRQT
WQDYRLQHKAGTVLTPLLGRKIPTDFIWTPDTVISNSVKTRKHKVTTNNE
KLDIYPNGTVFWGSRITVISKCKMDFRNYPMDIQSCSLVINSYAYLKEHL
EYKWKQDKVSIQSEEMAQYTVKSAYNLRRNANFSDLGTFSELVVTFTFAR
QISVTIIQLFFPATAIVSVSWVSLWIHKNCVSARVALCVTTMLTICAFWG
SVNRQLPRVNYPKAVDYYFIVSFLFIMLTLVEFTIVLNFDFDSLKTKSVK
KQSGKDTLKRENSLRNQLPKHTHHVLRRKISRLDANVLQGDLVCEIDNTG
RTVHYSLAKKEQWKKPKVDKNKMPYFFKYYPVTGKPATLDVIARFLFPFV
YFCFNVIFWKTYSL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_002835	XLOC_002835	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00005001	TCONS_00005001	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006028	GABAA/Glycine_rcpt
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha	PRINTS	PR00253	GABAARECEPTR	coord: 255..275 score: 42.94 coord: 281..302 score: 38.5 coord: 442..462 score: 37.67 coord: 315..336 score: 33.15
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 92..108 score: 37.9 coord: 172..186 score: 44.98 coord: 126..137 score: 46.76
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 47..251 e-value: 5.0E-53 score: 179.3
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 50..251 e-value: 5.7E-45 score: 153.3
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 50..251
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 260..364 e-value: 1.0E-19 score: 71.4
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 256..463
None	No IPR available	GENE3D	1.20.58.390		coord: 256..464 e-value: 9.2E-36 score: 122.5
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 172..186

Blast

[Close]

BLAST of TCONS_00005001-protein vs. Swiss-Prot (Human)
Match: GBRR1 (Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapiens GN=GABRR1 PE=2 SV=2)

HSP 1 Score: 220.705 bits (561), Expect = 1.541e-66
Identity = 139/423 (32.86%), Postives = 221/423 (52.25%), Query Frame = 0

Query:   54 LNQYDKNIRPNYTGKPIVVTVDLTVMAFGAINERGMTFATDLYFRQTWQDYRLQHKAGTVLTPLL-GRKIPTDFIWTPDTVISNSVKTRKHKVTTNNEKLDIYPNGTVFWGSRITVISKCKMDFRNYPMDIQSCSLVINSYAYLKEHLEYKWKQDKVSIQSEE---MAQYTVKSAYNLRRNANFSDLGTFSELVVTFTFARQISVTIIQLFFPATAIVSVSWVSLWIHKNCVSARVALCVTTMLTICAFWGSVNRQLPRVNYPKAVDYYFIVSFLFIMLTLVEFTIVLNFDFDSLKTKSVKKQSGKDTLKRENSLRNQLPKHTHHVLRRKISRLDANVLQGDLVCEIDN----TGR-----TVHYSLAKKEQWKKPKVDKNKMPYFFKYYPVTGKPATLDVIARFLFPFVYFCFNVIFWKTYS 463
            ++ +D ++RP + G  I V VD+ V +  +I+E  M F   LY R  W+D RL   +   L+    GR +    IW PD    +S ++  H  TT+N  L + P+G V +  R+TV + C MDF  +P+D Q+CSL I SYAY ++ L   WK+   S++++E   ++Q+ ++  +   + A +S  G ++ L + FT  R I   ++Q +FPAT +V +SWVS WI +  V ARV L +TT+LT+      VN  +PRV+Y KAVD Y  VSF+F+ L+++E+  V     + L T   +K         E  LR +LP  T  +   + + LD N   G+ V ++DN     G       V  +LA +    + K  ++       Y  +      +D  +R +FP  Y  FN+I+W  +S
Sbjct:   81 IDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKK--IWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAV-----NYLTTVQERK---------EQKLREKLP-CTSGLPPPRTAMLDGNYSDGE-VNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKSQRS------SYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS 479

The following BLAST results are available for this feature:

BLAST of TCONS_00005001-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00005001-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
GBRR1	1.541e-66	32.86	Gamma-aminobutyric acid receptor subunit rho-1 OS=...	[more]

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TCONS_00005001-protein (polypeptide) - C. hemisphaerica