TCONS_00004552-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004552-protein
Unique NameTCONS_00004552-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1646

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004552-protein ID=TCONS_00004552-protein|Name=TCONS_00004552-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1646bp
MADHMVDAATRAKMTTRWTKTDKLKYRSLFLFNKDNKFRILLYNISTSQI
FDFIILLAIIGSCILLTKQRQQQYSLTDKLILIDLILNLLFAFEALMKIV
SHGFVLHRHAYLRDPWNIFDFIVVLAGGLWDIAAVTTDGKSFSLKALRLF
RVFRPLRLIVKSNNLKVVLDTIIKSFNVLFHVLMFILLLIFLYAITGMEL
FGDTVYTACVYNGTGQLCDPFLLCDFGDTTFCPERFGLNASCMEYPSKGV
EYSHFENIFSSMLTVLQCITMEDWVLVAYDVAFYNSHYATWIYFISLIWI
GGYFAIDLLMGVLGNQYLRTKECAIIAMEKRKERERAERLLEEPKKPLCN
LWKILKPRLNQLGERISRQAAKLQTKFKPINDHMAFFYLVNLVVLADVLG
STYYGQNRPDALPSQLPTTYMGLKFSLFMFYVFENMIEGFSLGLHKVKKS
PYFMMSAGITITAGIELFLAITGWTNEVFVGISFIRAVTLVELFKLTRWW
ERLKMIINSLFETLKGVIYLFVLLFIVLANYALLGNQFXLFVLLFIVLAN
YALLGNQFFGDPEKNLPTTSGTFDSFGSSLLLTFVMLTGDNWTGIMFDTV
ELMNAPWEKVLTVLYFISFVVIGNFILMNVFLGIIVDNLTNDFEEKQIEQ
ANKERRKKQKMLISQVFKAKTQLMQKWKSSHENNGSEEENTENKNEAKKD
PNPTNTKNNKSSRLSEALKLVRKPVDPKVKDVAFFVDNTLKNTLVHFDDG
TTSSFKSDGSFMSTKSTIQVTAKTSKLSNTLGDGYGLGEDRDYRNSSSDD
GDSEEEDENPHTQIEDIHDMIRMSSRRRAYSLRLNPEINCPIPHHKALFL
FKHTNEFRRHIFWLVTSSKFTYAVCAAIVISCGLMALDDPLNRDPELTLW
LDRIDYVFSAVFLIEVILKSIAYGFVMGHKNCYLRSYMNIIDFVAVFFSV
FNIFIMLVGESEHLQFKTIRIIRVVRMLKISTDLKRVINCLLNSLQRITY
FLVLYVLILFIYAVIGVHLYHHALHVPSPINLVNASSNTPYLMKDSHGSI
SSSPEMSWEGVKLSFNNFGHGMMTLFVASTLDDWFLVLTRLTTAGHSEVT
GIVFLLSFLILMSFILMNVFIGFVVVLFHKEKEKDEQYNVLNTSGQECLV
TALSANPTQLYDQPHGRFKIIFWRLASHPWFQKLSMIMILMNTGFMMTKH
TRQDEVFFQIQRLSNIVFTSLFTIEIAIKLTAFSMKALLRDRWLLFDAIV
ILGSWFDIVLEELQIPFLKLSIFRLFRVARLAQVLGKGGNLRQLFATFLK
SMKCVPSIACLMGLILYFYAILGMNLFGRLKIDDTTAINSNANFQSFTAA
ILVLIRVTTLDQWQGIMLTCADTHLMNCANGSNENCGTTISYFYFGSFVF
ICSYIMTNLFLAFIMDNFVYLTHDWSELDSRHIHLFTAIWGQYDKSGAGF
IKKEKLVSLLKNLNPPLGNGKMCPDRTIYARILKLRVPVEKDGTVRFNEL
LMTLVLDFLQLKVDNVILREDIHKLFPIINDDLLDRVLPLSYDPRIINET
EKEFYQDCASYVITGYCRLYKSSLTAAFKIKDNANSSKEVQNISRGKFAS
LVSRSARDVPSIEITEPRGSKSLTNLDLERGDLVQKIKVAERSRTW
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002560XLOC_002560Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004552TCONS_00004552Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002077VDCCAlpha1
IPR005821Ion_trans_dom
IPR031649GPHH_dom
IPR011992EF-hand-dom_pair
Vocabulary: Cellular Component
TermDefinition
GO:0005891voltage-gated calcium channel complex
GO:0016020membrane
Vocabulary: Biological Process
TermDefinition
GO:0070588calcium ion transmembrane transport
GO:0055085transmembrane transport
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005245voltage-gated calcium channel activity
GO:0005216ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0070588 calcium ion transmembrane transport
biological_process GO:0006811 ion transport
biological_process GO:0055085 transmembrane transport
cellular_component GO:0016020 membrane
cellular_component GO:0005891 voltage-gated calcium channel complex
molecular_function GO:0005216 ion channel activity
molecular_function GO:0005245 voltage-gated calcium channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 636..661
NoneNo IPR availableGENE3D1.10.238.10coord: 1430..1524
e-value: 2.8E-8
score: 33.2
NoneNo IPR availableGENE3D1.10.287.70coord: 1177..1423
e-value: 2.0E-43
score: 147.8
coord: 47..321
e-value: 5.9E-43
score: 146.3
coord: 382..643
e-value: 1.6E-20
score: 72.9
coord: 866..1131
e-value: 2.4E-35
score: 121.4
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 1061..1131
coord: 868..1023
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 1178..1419
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 48..204
coord: 251..318
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 391..542
coord: 569..645
IPR002077Voltage-dependent calcium channel, alpha-1 subunitPRINTSPR00167CACHANNELcoord: 571..597
score: 42.3
coord: 1294..1308
score: 40.0
coord: 166..181
score: 44.63
coord: 1342..1354
score: 50.24
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 870..1134
e-value: 9.5E-40
score: 136.3
coord: 1178..1425
e-value: 1.1E-43
score: 149.1
coord: 385..640
e-value: 3.5E-24
score: 85.3
coord: 49..321
e-value: 1.2E-45
score: 155.6
IPR031649Voltage-dependent L-type calcium channel, IQ-associated domainPFAMPF16905GPHHcoord: 1428..1497
e-value: 4.1E-18
score: 64.8
IPR011992EF-hand domain pairSUPERFAMILY47473EF-handcoord: 1423..1528

Blast
BLAST of TCONS_00004552-protein vs. Swiss-Prot (Human)
Match: CAC1C (Voltage-dependent L-type calcium channel subunit alpha-1C OS=Homo sapiens GN=CACNA1C PE=1 SV=4)

HSP 1 Score: 404.445 bits (1038), Expect = 5.196e-115
Identity = 269/878 (30.64%), Postives = 440/878 (50.11%), Query Frame = 0
Query:  788 GEDRDYRNSSSDD-GDSEEEDENPHTQIEDIHDM------IRMSSRRRAYSLRLNPEINCPIPHHKALFLFKHTNEFRRHIFWLVTSSKFTYAVCAAIVISCGLMALDDPLNRDP-------------------ELTLW-LDRIDYVFSAVFLIEVILKSIAYGFVMGHKNCYLRSYMNIIDFVAVFFSVFNIFIMLVGESEHLQFKTIRIIRVVRMLKISTDLKRVINCLLNSLQRITYFLVLYVLILFIYAVIGVHLYHHALHVPSPIN-LVNASSNTPYLM-KDSHGSISSSPEMSWEGVKLSFNNFGHGMMTLFVASTLDDWFLVLTRLTTAGHSEVTGIVF---------LLSFLILMSFILMNVFIGFVVVLFHKEKEKDEQYNVLNTSGQECLVTALSANPTQLYDQPHGRFKIIFWRLASHPWFQKLSMIMILMNTGFMMTKHTRQDEVFFQIQRLSNIVFTSLFTIEIAIKLTAFSMKALLRDRWLLFDAIVILGSWFDIVLEELQIPF-------------------------------------------LKLSIFRLFRVARLAQVLGKGGNLRQLFATFLKSMKCVPSIACLMGLILYFYAILGMNLFGRLKIDDTTAINSNANFQSFTAAILVLIRVTTLDQWQGIMLTC-------ADTHLMNCANGSNENCGTTISYFYFGSFVFICSYIMTNLFLAFIMDNFVYLTHDWSELDSRHIHLFTAIWGQYDKSGAGFIKKEKLVSLLKNLNPPLGNGKMCPDRTIYARILKLRVPVEKDGTVRFNELLMTLVLDFLQLKVD------NVILREDIHKLFPIINDDLLDRVLPLSYDPRIINETEKEFYQDCASYVITGYCRLYK 1571
            GE       + DD   +E ED++P+   E   +       + +  R R  S     E   P+P   A F+F   N FR     +V  + FT  +   I++S   +A +DP+                       E+ L  L   DYVF+++F +E+ILK  AYG  + HK  + R+Y NI+D + V  S+ +  I     +     + +R++R +R +  +  LK V+ C+  +++ I   +++  L+ F++A IGV L+   L+  S  +    A     Y+  KD           SWE  K  F+N    MM LF  ST + W  +L R +   H+E  G ++          + ++I+++F +MN+F+GFV+V F ++ E++ +   L+ + ++C+  AL A P + Y  P  + +   W + +  +F+ L  ++IL+NT  +  +H  Q  +F     + N++FT LFT+E+ +KL AF  K    D W +FD ++++GS  D++L E    F                                           + ++ FRLFRV RL ++L +G  +R L  TF+KS + +P +A L+ ++ + YA++GM +FG++ ++DTT IN N NFQ+F  A+L+L R  T + WQ IML C        ++   N   G    CG++ + FYF SF  +C++++ NLF+A IMDNF YLT DWS L   H+  F  IW +YD    G IK   +V+LL+ + PPLG GK+CP R    R++ + +P+  DGTV FN  L  LV   L++K +      N  LR  I K++   +  LLD+V+P + D  +   T  +FY   A+++I  Y R +K
Sbjct:  813 GESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFL-HKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYR-SIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRY-IPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETP-CGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV---TVGKFY---ATFLIQEYFRKFK 1680          

HSP 2 Score: 240.736 bits (613), Expect = 1.016e-63
Identity = 218/773 (28.20%), Postives = 349/773 (45.15%), Query Frame = 0
Query:   12 AKMTTRWTKTDKLKYRSLFLFNKDNKFRILLYNISTSQIFDFIILLAIIGSCILLTK----QRQQQYSLTDKLILIDLILNLLFAFEALMKIVSHGFVLHRHAYLRDPWNIFDFIVVLAGGLWDI----------AAVTTDGKSFSLKALRLFRVFRPLRLIVKSNNLKVVLDTIIKSFNVLFHVLMFILLLIFLYAITGMELFGDTVYTACVYNGTGQLCDPFLLCDFGDTTFCPERFGLNASCM---------EYPSKGVEYSHFENIFSSMLTVLQCITMEDWVLVAYDVAFYNSHYATWIYFISLIWIGGYFAIDLLMGVLGNQYLRTKECAIIA--MEKRKERERAERLL------------------------EEPKK---PLCNLWKILKPRL-------NQLGERISRQAAK-------------LQTKFKPINDHMAFFYLVNLVVLADVL--GSTYYGQNRPDALPSQLPTTYMGLKFSLFMFYVFENMIEGFSLGLHKVKKSPYFMMSAGITITAGIELFLAITGWTNEVFVGISFIRAVTLVELFKLTRWWERLKMIINSLFETLKGVIYLFVLLFIVLANYALLGNQFXLFVLLFIVLANYALLGNQFFGDPEKNLPTTSGTFDSFGSSLLLTFVMLTGDNWTGIMFDTVELMNAP-WEKVLTVLYFISFVVIGNFILMNVFLGIIVDNLTNDFEEKQIEQANKERRKKQKMLISQVFKAKTQLMQKWKSSHENNGSEEENTENKNEAKKDPNPTNTKNN 709
             K   + + T     R+L      N  R    +I   + F+ IILL I  +C+ L            +    L  ++ +  ++F  EA +K++++G + H +AYLR+ WN+ DFI+V+ G    I           A+   G  F +KALR FRV RPLRL+    +L+VVL++IIK+   L H+ + +L +I +YAI G+ELF   ++  C YN  G    P       D + C    G    C          + P  G+  ++F+N   +MLTV QCITME W  V Y V         WIYF++LI IG +F ++L++GVL  ++ + +E A      +K +E+++ E  L                        E+P+    P      +    +          G R++ + +K              + K +       F++LV  +V  + L   S +Y Q      P+ L         +L   +  E +++ +SLGL     S +      +     +E  L  T   + +  GIS +R V L+ +FK+TR+W  L  ++ SL  +++ +  L +LLF+ +  ++LLG Q               L G +F  D    + T   TFD+F  SLL  F +LTG++W  +M+D +     P +  +L  +YFI   + GN+IL+NVFL I VDNL  D E     Q  +E  K++K L       K Q + +  +  E   S+EE  E K+      +P  TK N
Sbjct:   87 GKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTC-YNQEGIADVPAE----DDPSPCALETGHGRQCQNGTVCKPGWDGPKHGI--TNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ------PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPL--GISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQ---------------LFGGKFNFD---EMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA-DAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGE---SKEEKIELKSITADGESPPATKIN 822          

HSP 3 Score: 110.923 bits (276), Expect = 3.988e-24
Identity = 85/315 (26.98%), Postives = 152/315 (48.25%), Query Frame = 0
Query:  846 KALFLFKHTNEFRRHIFWLVTSSKFTYAVCAAIVISCGLMALDDPLNRDPE--LTLWLDRIDYVFSAVFLIEVILKSIAYGFVMGHKNCYLRSYMNIIDFVAVFFSVFNIFI----------MLVGESEHLQFKTIRIIRVVRMLKIST---DLKRVINCLLNSLQRITYFLVLYVLILFIYAVIGVHLY----HHALHVPSPINLVNASSN-TPYLMKDSHGSISSSPEM---SWEGVK---LSFNNFGHGMMTLFVASTLDDWFLVLTRLTTAGHSEVTGIVFLLSFLILMSFILMNVFIGFVVVLFHKEKEK 1134
            +AL      N  RR    +V    F   +   I  +C  +A+  P   D        L+R++Y+F  +F +E  LK IAYG +  H N YLR+  N++DF+ V   +F+  +           L G+      K +R  RV+R L++ +    L+ V+N ++ ++  + +  +L + ++ IYA+IG+ L+    H   +    I  V A  + +P  ++  HG    +  +    W+G K    +F+NF   M+T+F   T++ W  VL  +  A   +   I F ++ +I+ SF ++N+ +G +   F KE+EK
Sbjct:  102 RALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLF-HPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYF-VTLIIIGSFFVLNLVLGVLSGEFSKEREK 414          
The following BLAST results are available for this feature:
BLAST of TCONS_00004552-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CAC1C5.196e-11530.64Voltage-dependent L-type calcium channel subunit a... [more]
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