TCONS_00002428-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00002428-protein
Unique NameTCONS_00002428-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length336

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00002428-protein ID=TCONS_00002428-protein|Name=TCONS_00002428-protein|organism=Clytia hemisphaerica|type=polypeptide|length=336bp
VEMKETSTYGKVLENPFENDENSGPEINPNSLTIVQMLSNGKSLDISKGA
LLKNGEMKTVVIKTLKETATESDRIDFLQEASLVGKMNHTNIIKYEGIIL
KSQPHTIALEYMLNGTLNLYLKKHDMKLTNLQLLGMARGVASGMKYLNEL
GFIHRDIAARNVVLADNGECKISNFGMCRELDGKGCFMAKDGKIAIIWAA
PESAHQKIFTTASDVWSYGILLWEIMSYGERPYWNMESPADVLEAIDQGY
RLPPLKNCPRVAYDMMLECWEIEHTKRPTINEILNRIDKWIDNPEELLDE
ATPDGYSSLYSNHSNKNGADYAEISDYADLKSVNDW
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001306XLOC_001306Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00002428TCONS_00002428Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR000719Prot_kinase_dom
IPR020635Tyr_kinase_cat_dom
IPR008266Tyr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0004713protein tyrosine kinase activity
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 109..122
score: 42.66
coord: 146..164
score: 50.75
coord: 258..280
score: 37.86
coord: 194..204
score: 44.58
coord: 213..235
score: 61.45
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 33..286
e-value: 4.8E-77
score: 258.7
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 32..291
e-value: 1.2E-27
score: 107.9
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 32..291
score: 34.195
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 32..287
e-value: 1.2E-89
score: 313.8
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 40..132
e-value: 0.038
score: 10.0
coord: 121..329
e-value: 5.4E-46
score: 155.1
NoneNo IPR availableGENE3D3.30.200.20coord: 13..118
e-value: 1.0E-13
score: 50.7
NoneNo IPR availableGENE3D1.10.510.10coord: 119..304
e-value: 8.0E-45
score: 151.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..26
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 152..164
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 25..310

Blast
BLAST of TCONS_00002428-protein vs. Swiss-Prot (Human)
Match: EPHA3 (Ephrin type-A receptor 3 OS=Homo sapiens GN=EPHA3 PE=1 SV=2)

HSP 1 Score: 283.878 bits (725), Expect = 5.850e-88
Identity = 133/287 (46.34%), Postives = 199/287 (69.34%), Query Frame = 0
Query:   14 ENPFENDENSGPEINPNSLTIVQMLSNGKSLDISKGAL-LKNGEMKTVVIKTLKETATESDRIDFLQEASLVGKMNHTNIIKYEGIILKSQPHTIALEYMLNGTLNLYLKKHDMKLTNLQLLGMARGVASGMKYLNELGFIHRDIAARNVVLADNGECKISNFGMCREL--DGKGCFMAKDGKIAIIWAAPESAHQKIFTTASDVWSYGILLWEIMSYGERPYWNMESPADVLEAIDQGYRLPPLKNCPRVAYDMMLECWEIEHTKRPTINEILNRIDKWIDNPEEL 297
            E+P +       E++  +++I +++  G+  ++  G L L + +  +V IKTLK   TE  R DFL EAS++G+ +H NII+ EG++ KS+P  I  EYM NG+L+ +L+KHD + T +QL+GM RG+ASGMKYL+++G++HRD+AARN+++  N  CK+S+FG+ R L  D +  +  + GKI I W +PE+   + FT+ASDVWSYGI+LWE+MSYGERPYW M S  DV++A+D+GYRLPP  +CP   Y +ML+CW+ +   RP   +I++ +DK I NP  L
Sbjct:  603 EDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEM-SNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSL 888          
The following BLAST results are available for this feature:
BLAST of TCONS_00002428-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
EPHA35.850e-8846.34Ephrin type-A receptor 3 OS=Homo sapiens GN=EPHA3 ... [more]
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