TCONS_00002230-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00002230-protein
Unique NameTCONS_00002230-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length672

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00002230-protein ID=TCONS_00002230-protein|Name=TCONS_00002230-protein|organism=Clytia hemisphaerica|type=polypeptide|length=672bp
FWQFETNNLMVLISKWNKNKKSKLTYKNNTHKDKMGYKNFKNQDFKSIKS
QCASNNQLFEDPEFPANDRALYFSKQPSFKAEWKRPKELCDEPHMFVQGA
DAADVTQGRVGNCWFVAAAACLALEKDLWKKVIPDYKEQIFSPEKPEDYQ
GIFHFRFWRFGEWTDVVIDDRLPTINGELIYVKSKAKNEFWSALLEKAYA
KMSGSYEALESGNPADALVDFTGGTSETIDLVKGGYKDDLEKRKELHQKL
VKLLSRNAMASASIKVTNRDEMEKQLDTGLVKGHAYGLSDVKKIEKGMFS
SESDKIYLVKLRNPWGEKEWNGPWSDGSTEWNTLSQKDKDKIGVKVENDG
EFWMSFEDFCTQFTTVTICMLVNTSMFTIHKTYNEGFYKGSWEGRNAGGC
VNNKETFLHNPQIKFDMTGSKLKDVAFISLMQPDMRALKHEGKANNTMGF
HVMRVEGNRSYRVHQNYEKAGDSSFINSREIFARLELDPGRYIIVPSTFE
PNTSGQFLLRVYTDHSNHMRPLVEEKPEPGCLSCLPCCKPPGVQLSVTVT
EVNNLKKKGSMSMTVDPYVVIECEGTKVSSYHLTDNVNPKISYGGLFYVK
KPDSTYKVQVWDHNVIKDTFLGETTEQTIDVNNKLVQITHQLMDKKDRNG
EQPKADGTVTIRVAASSNLEFM
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001180XLOC_001180Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00002230TCONS_00002230Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR022684Calpain_cysteine_protease
IPR000008C2_dom
IPR001300Peptidase_C2_calpain_cat
IPR022683Calpain_III
IPR022682Calpain_domain_III
IPR000169Pept_cys_AS
IPR033883C2_III
Vocabulary: Cellular Component
TermDefinition
GO:0005622intracellular
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
Vocabulary: Molecular Function
TermDefinition
GO:0004198calcium-dependent cysteine-type endopeptidase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0005622 intracellular
molecular_function GO:0004198 calcium-dependent cysteine-type endopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 237..257
NoneNo IPR availableGENE3D3.90.70.10coord: 224..374
e-value: 7.3E-43
score: 145.0
NoneNo IPR availableGENE3D2.60.120.380coord: 375..523
e-value: 2.1E-36
score: 124.5
NoneNo IPR availableSUPERFAMILY54001Cysteine proteinasescoord: 36..381
IPR022684Peptidase C2, calpain familyPRINTSPR00704CALPAINcoord: 396..413
score: 56.48
coord: 486..514
score: 53.33
coord: 179..202
score: 68.61
coord: 83..105
score: 45.36
coord: 204..231
score: 52.98
coord: 149..174
score: 74.74
coord: 107..123
score: 57.65
coord: 348..369
score: 58.94
coord: 43..66
score: 40.14
IPR000008C2 domainSMARTSM00239C2_3ccoord: 544..643
e-value: 0.0065
score: 25.7
IPR000008C2 domainGENE3D2.60.40.150coord: 543..667
e-value: 2.4E-13
score: 49.8
IPR000008C2 domainPFAMPF00168C2coord: 544..625
e-value: 1.0E-8
score: 35.3
IPR000008C2 domainPROSITEPS50004C2coord: 544..625
score: 10.308
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 527..651
IPR001300Peptidase C2, calpain, catalytic domainSMARTSM00230cys_prot_2coord: 40..380
e-value: 2.0E-168
score: 575.5
IPR001300Peptidase C2, calpain, catalytic domainPFAMPF00648Peptidase_C2coord: 59..369
e-value: 2.1E-118
score: 394.6
IPR001300Peptidase C2, calpain, catalytic domainPROSITEPS50203CALPAIN_CATcoord: 58..372
score: 73.087
IPR001300Peptidase C2, calpain, catalytic domainCDDcd00044CysPccoord: 48..369
e-value: 2.22553E-121
score: 365.887
IPR022683Peptidase C2, calpain, domain IIISMARTSM007202calcoord: 382..520
e-value: 1.1E-43
score: 161.1
IPR022682Peptidase C2, calpain, large subunit, domain IIIPFAMPF01067Calpain_IIIcoord: 390..516
e-value: 2.6E-34
score: 118.4
IPR022682Peptidase C2, calpain, large subunit, domain IIISUPERFAMILY49758Calpain large subunit, middle domain (domain III)coord: 387..521
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 107..118
IPR033883Calpain subdomain IIICDDcd00214Calpain_IIIcoord: 381..522
e-value: 1.55122E-41
score: 147.06

Blast
[Close]
BLAST of TCONS_00002230-protein vs. Swiss-Prot (Human)
Match: CAN5 (Calpain-5 OS=Homo sapiens GN=CAPN5 PE=1 SV=2)

HSP 1 Score: 600.897 bits (1548), Expect = 0.000e+0
Identity = 298/643 (46.35%), Postives = 415/643 (64.54%), Query Frame = 0 
Query:   38 KNFKNQDFKSIKSQCASNNQLFEDPEFPANDRALYFSKQPSFKAEWKRPKELCDEPHMFVQGADAADVTQGRVGNCWFVAAAACLALEKDLWKKVIPDYKEQIFSPEKPEDYQGIFHFRFWRFGEWTDVVIDDRLPTINGELIYVKSKAKNEFWSALLEKAYAKMSGSYEALESGNPADALVDFTGGTSETIDLVKGGYKDDLEKRKELHQKLVKLLSRNAMASASIKVTNRDEMEKQLDTGLVKGHAYGLSDVKKIEKG---MFSSESDKIYLVKLRNPWGEKEWNGPWSDGSTEWNTLSQKDKDKIGVKVENDGEFWMSFEDFCTQFTTVTICMLVNTSMFTIHKTYNEGFYKGSW------EGRNAGGCVNNKETFLHNPQIKFDMTGSKLKDVAFISLMQPDMRALKHEGKANN-TMGFHVMRVEGNRSYRVHQNYEKAGDSSFINSREIFARLELDPGRYIIVPSTFEPNTSGQFLLRVYTDHSNHMRPLVEEKPEPGCLSCLPCCKPPGVQLSVTVTEVNNLKKKGSMSMTVDPYVVIECEGTKVSSYHLTDNVNPKISYGGLFYVKKPDSTYKVQVWDHNVIKDTFLGETTEQTIDVNNKLVQITHQLMDKKDRNGEQPK-ADGTVTIRVAASSNL 669
            K +++Q++ +++  C     LFEDP FPA D +LY+   P     WKRPK +C++P +FV G  + D+ QG+VGNCWFVAA + LA  + LW+KVIPD+KEQ + PEKP  Y GIFHF FWRFGEW DVVIDDRLPT+N +LIY  S ++NEFW AL+EKAYAK++G Y+AL+ GN ADALVDFTGG SE IDL +G + +D  KR +L ++++K+ SR  + SASIK     +ME +L  GLVKGHAY ++DV+K+  G   +   +S+K+ +++LRNPWGE+EWNGPWSD S EW  +S+ +++K+GV V++DGEFWM+FED C  FT +  C ++NTS  +IHKT+ E    G+W           GGC+N+K+TF  NPQ  F++   K +D   I + Q   R+ + EGK  N  +GF + +VE NR YR+H    KA  S +INSR +F R +   GRY+I+P+TFEP  +G+FLLRV+TD  ++ R L  ++P   C S L  C  P +   V V     LK   + +   + YV+I+CEG KV S        P+ +  G+FY KK      VQVW+H V+KD FLG+   +  D +N  +Q  H L   +DRN  QP    GTV + + +S++L
Sbjct:    6 KPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLYYKGTPGPAVRWKRPKGICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEV--KKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSL--CGYPQLVTQVHVLGAAGLKDSPTGA---NSYVIIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLSQPITVQVWNHRVLKDEFLGQVHLKA-DPDN--LQALHTL-HLRDRNSRQPSNLPGTVAVHILSSTSL 637
The following BLAST results are available for this feature:
BLAST of TCONS_00002230-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CAN50.000e+046.35Calpain-5 OS=Homo sapiens GN=CAPN5 PE=1 SV=2[more]
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