TCONS_00001134-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00001134-protein
Unique NameTCONS_00001134-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1927

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00001134-protein ID=TCONS_00001134-protein|Name=TCONS_00001134-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1927bp
MDKAEALFNDKIDGNVVGPSTDSSGSELIYLCYNGNFQTIQLLIKSNQQL
LLDKACGGIGDCPKVEHKQTWKKLQEVLLRKHETYTVGDLLLCVACILQN
HTLVELLTNRGVDVNHGTTKHELLSPLYIACINEDIEMITYLMNNKAEVI
SVIAKEFPTLISQVLEKRIEEYKVPRRKGKMKNSQKKKTMYRLCWENSHL
HALNKDWFMVEKYNITRVELPRNKLTKLVDGFFQLLPLLEELDVASNHLM
ALPSDHLANSKLKRLDVSSNQLRSLPESLFFNQNIVVIDASSNQLSSLPH
THTNWKCSALEKFVCSKNELTELPKSIAGANRIQILNLSRNKFEVFNRWW
KCPLVDVNLSFNHIKDFTLKTDSFWSKTIKTLNLTRNNLDFIPSSILHLT
KLENLKLARNALKTLPRPDLWKTKRLLDLDLSYNQITTTPITDGFLDLET
EEVEYNNTCELPVKIFADTLQSLNLAHNLLDEIPETLCQLKALGRLDLSH
NTGLTFLPPKLGLLKNIWSLNLSGLDIKNVPHKFEGLNHVKVLSFLRAKL
RKSKPFNRIKLMLVGLQGRGKTTLVHAIQGKPPPPNISTVGIIVEQFVLP
LRNQYYFYSSPSPEIMFSVWDLAGQQVYYATHQCFLSGKTLYLVVYNVTH
GSEGIDSLGSWLLNIQARAPNSRCIIVGTHVDKMPVYRKEETLIKYRKQI
MDKFMKEGFPAISKCVFVSGTSNENIEELREVVYKEAEAMNHQSDLGKLA
PISYLELYDQIIMESVRRNEQQRPPVLTTEEMLQLAEQNTNNDIMDFEEL
CTASQFLHENGVLLHFNDHLRGLNNLFFIDPSWLIDIVALVVTVRQRNPY
VQKGYITEQELLYILKNPWLPEKFIPQYLRLLERFEILLSLEDGKFLIPC
MLSEEKPDIEHKMLHVITSEEIRHHQINVERTTNYLTRNYHMQYVPAGFW
ARFIARLVIAVQKWSLQIQQDGNTGYTKQLWRKGLMVTYEDGYFLIESFH
DQELRPKKWSNQGVSITVWSKTKDFSVMGFIVDHMEMLITEWYPGLEGIN
DYGDNLVQKLISCPICCAQKAIDLVQCCDQNTISLRNHYGSFFRNEFFIN
QFPLDTCAYAAIDHQEIICVKHPDQPVRLELLIPEIMMTDLPQKYCITED
SLDFDPHTSRKLGDGGAGVVYLGRYDDEDVAIKRSHSVIMKESQQGEGAF
DPSDRSVTQLLSLDDGRVVKSFWEMRQEVLVLCTLQHANIVKFLGVCFSP
LCFVIEFAPMGSLFGILEKEQKKAELPILGMQLTYLILFQITEAIKYLHS
WNIIYRDLKSENVLVMSLDPQQTINVKLSDYGIAAFATPQGVTGVAGTPA
FQAPEIQKDYTYDEKVDIFSYGIWMYELLTGCLPYLEYRSSSEIKKAIQT
GVRPDFRKEGYRLSYPYAELLMNECWQQSPPSRPSSYEMSAFFKSTDMMT
LRALYPSNQDSIYLEHVTCHTIWHTNFPDTMQCDPSDKILLWNNKKENRT
FVLFDLKCHTIRYNDSLPGPRVSCACQVEENVWLGCETNRVIEIFGFVNS
EVPKVLWTFSDFEDDILMMQKHESEGILTVFTTLANGTLVIFTKMVHHRK
SELIEEEDLWSRQVINLQTRGRPAKCMTITNNQTELWVGSGNCIVVLNIQ
TREIVDRLAVTKMSDQNALISVMCGDGEDTVWTSLWKSGFVTQWNVKERT
KTFEYYCSEDKPLHRGVRYECGTFKNLFRQPTIEERDLKVKVQSPICEEM
KTFRSNNNRLAEDTLYKRPSLRFPTRTYVRHKSSTASTSSTLDELTSNST
SKRNNMFNKTVTALRFVKGILWIGRTNGDVIVIDHVTGHVTGVLADDHLK
LLGNDNRYIQSMVPMEKDSKMTACVRIRNEARGRRSLVPNLSLERKQKEC
YQILVYDIWPSGQFNHFNDKVQEIFNE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000630XLOC_000630Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00001134TCONS_00001134Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR003591Leu-rich_rpt_typical-subtyp
IPR000719Prot_kinase_dom
IPR002110Ankyrin_rpt
IPR020683Ankyrin_rpt-contain_dom
IPR013684MIRO-like
IPR032675L_dom-like
IPR015943WD40/YVTN_repeat-like_dom
IPR001611Leu-rich_rpt
IPR032171COR
IPR008271Ser/Thr_kinase_AS
IPR020859ROC_dom
IPR011047Quinoprotein_ADH-like_supfam
IPR027417P-loop_NTPase
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0005515protein binding
GO:0005525GTP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007264small GTPase mediated signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007264 small GTPase mediated signal transduction
molecular_function GO:0005524 ATP binding
molecular_function GO:0005525 GTP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003591Leucine-rich repeat, typical subtypeSMARTSM00369LRR_typ_2coord: 399..423
e-value: 5.7
score: 15.3
coord: 260..282
e-value: 0.63
score: 19.1
coord: 236..259
e-value: 2.6
score: 17.1
coord: 470..490
e-value: 27.0
score: 9.7
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 1156..1443
e-value: 4.4E-43
score: 159.1
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 1158..1438
e-value: 1.0E-39
score: 136.4
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 1156..1443
score: 34.732
NoneNo IPR availableSMARTSM00364LRR_bac_2coord: 259..278
e-value: 0.11
score: 21.6
coord: 399..418
e-value: 220.0
score: 3.5
coord: 467..486
e-value: 61.0
score: 7.7
coord: 236..255
e-value: 53.0
score: 8.2
coord: 282..301
e-value: 97.0
score: 6.2
coord: 376..395
e-value: 360.0
score: 1.8
coord: 307..326
e-value: 290.0
score: 2.6
NoneNo IPR availableGENE3D3.30.200.20coord: 923..1293
e-value: 1.1E-24
score: 86.5
NoneNo IPR availableGENE3D3.40.50.300coord: 557..791
e-value: 1.6E-23
score: 82.4
NoneNo IPR availableGENE3D1.10.510.10coord: 1294..1446
e-value: 4.4E-30
score: 103.7
NoneNo IPR availableCDDcd00204ANKcoord: 88..149
e-value: 1.59905E-5
score: 44.2967
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 122..152
e-value: 1.0
score: 18.4
coord: 87..116
e-value: 45.0
score: 12.9
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 19..191
e-value: 6.8E-11
score: 41.4
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 87..149
score: 10.79
IPR020683Ankyrin repeat-containing domainSUPERFAMILY48403Ankyrin repeatcoord: 84..149
coord: 28..52
IPR013684Mitochondrial Rho-likePFAMPF08477Roccoord: 560..683
e-value: 3.9E-21
score: 75.4
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 192..294
e-value: 4.6E-14
score: 51.4
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 295..362
e-value: 3.1E-9
score: 35.7
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 363..556
e-value: 2.0E-27
score: 95.1
IPR032675Leucine-rich repeat domain, L domain-likeSUPERFAMILY52058L domain-likecoord: 215..546
IPR015943WD40/YVTN repeat-like-containing domainGENE3D2.130.10.10coord: 1447..1596
e-value: 0.083
score: 11.6
IPR015943WD40/YVTN repeat-like-containing domainGENE3D2.130.10.10coord: 1612..1863
e-value: 2.9E-6
score: 26.0
IPR001611Leucine-rich repeatPFAMPF13855LRR_8coord: 379..436
e-value: 3.9E-7
score: 29.6
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 261..282
score: 7.681
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 238..259
score: 5.255
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 378..399
score: 6.133
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 425..446
score: 6.287
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 353..374
score: 4.893
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 284..305
score: 5.186
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 469..490
score: 7.481
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 492..514
score: 5.687
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 401..422
score: 6.064
IPR032171C-terminal of Roc (COR) domainPFAMPF16095CORcoord: 751..986
e-value: 8.2E-28
score: 97.4
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 1303..1315
IPR020859Roc domainPROSITEPS51424ROCcoord: 552..740
score: 42.392
IPR011047Quinoprotein alcohol dehydrogenase-like superfamilySUPERFAMILY50998Quinoprotein alcohol dehydrogenase-likecoord: 1798..1844
coord: 1469..1696
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 557..751
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 1220..1478
coord: 1159..1192

Blast
BLAST of TCONS_00001134-protein vs. Swiss-Prot (Human)
Match: LRRK1 (Leucine-rich repeat serine/threonine-protein kinase 1 OS=Homo sapiens GN=LRRK1 PE=1 SV=3)

HSP 1 Score: 711.064 bits (1834), Expect = 0.000e+0
Identity = 548/1872 (29.27%), Postives = 865/1872 (46.21%), Query Frame = 0
Query:   91 LLCVACILQNHTLVELLT-NRGVDV-NHGTTKHELLS----PLYIACINEDIEMITYLMNNKAEVISVIAKEFPTLISQVLEKR-IEEYKVPRRKGKMKNSQKKKTMYRLCWENSHLHALNKDWFMVEKYNITRVELPRNKLTKLVDGFFQLLPLLEELDVASNHLMALP----SDHLANSKLKRLDVSSNQLRSLPESLFFNQNIVVIDASSNQLSSL--PHTHTNW-KCSALEKFVCSKNELTELPK-SIAGANRIQILNLSRNKFEVFNRWWKCPLVDVNLSFNHIKDFTLKTDSFWSKTIKTLNLTRNNLDFIPSSILHLTKLENLKLARNALKTLPRPDLWKTKRLLDLDLSYNQITTTPITDGFLDLETEEVEYNNT-------------CELPVKIFADTLQSLNLAHNLLDEIPETLCQLKALGRLDLSHNTGLTFLPPKLGLLKNIWSLNLSGLDIKNVPHKFEGLNHVKVLSFLRAKLRKSKPFNRIKLMLVGLQGRGKTTLVHAIQGKPPPPNI---STVGIIVEQFVLPLRNQYYFYSSPSPEIMFSVWDLAGQQVYYATHQCFLSGKTLYLVVYNVTHGSEGIDSLGSWLLNIQARAPNSRCIIVGTHVDKMPVYRKEETLIKYRKQIM------DKFMKEGFPAIS--KCVFVSGTSNENIEELREVVYKEAEAMNH-------QSDLGKLAPISYLELYDQIIMESVRRNEQQRPPVLTTEEMLQLAEQNTNNDIMDFEELCTASQFLHENGVLLHFNDHLRGLNNLFFIDPSWLIDIVALVVTVRQRNPYVQKGYITEQELLYILKNPWLPEKFIPQYLRLLERFEILLSLEDGKFLIPCMLSEEKPDIE-HKMLHVITSEEIRHHQINVERTTNYLTRNYHMQYVPAGFWARFIARLVIAVQKWSLQIQQDGNTGYTKQ---------------------------LWRKGLMVTYEDGYFLIESFHDQELRPKKWSNQGVSITVWSKTKDFSVMGFIVDHMEMLITEWYPGLEGINDYGDNLVQKLISCPICCAQKAIDLVQCCDQNTISLRNHYGSFFRNEFFINQFPLDTCAYAAIDHQEIICVKHPDQPVRLELLIPEIMMTDLPQKYCITEDSLDFDPHTSRKLGDGGAG-VVYLGRYDDEDVAIKRSHSVIMKESQQGEGAFDPSDRSVTQLLSLDDGRVVKSFWEMRQEVLVLCTLQHANIVKFLGVCFSPLCFVIEFAPMGSLFGILEKEQKKAELPILGMQLTYLILFQITEAIKYLHSWNIIYRDLKSENVLVMSLDPQQTINVKLSDYGIAAFATPQGVTGVAGTPAFQAPEIQKDYTYDEKVDIFSYGIWMYELLTGCLPYLEYRSSSEIKKAIQTGVRPDFRKEGYRLSYPYAELLMNECWQQSPPSRPSSYEMSAFFKSTDMMT-LRALYPSNQDSIYLEHVTCHTIWHTNFPDTMQCDPSDKILLWNNKKENRTFVLFDLKCHTIRYND-SLPGPRVSCACQVEENVWLGCETNRV----IEIFGFVNS-----EVPKVLWTF---SDFEDDILMMQKHESEGILTVFTTLANGTLVIFTKMVHH---RKSELIEEEDLWSRQVINLQTRGRPAKCMTITNNQTELWVGSGNCIVVLNIQTREIVDRLAVTKMSDQNALISVMC---GDGEDTVWTSLWKSGFVTQWNVKERTKTFEYYCSEDKPLH-----RGVRYECGTFKNLFRQPTIEERDLKVKVQSPICEEMKTFRSNNNRLAEDTLYKRPSLRFPTRTYVR---------------------------HKSSTASTSSTLDELTSNSTSKRNNMFNKTVTALRF--VKGILWIGRTNGDVIVI 1833
            +L +AC   +  +V+LL    G D  ++   K+E       PLY A  + + ++  +L+ + A   S I  + P     +L K  IE   +P       +S   KT  R+ W +  L  ++ DW +     IT ++L  N L  L       L  L +L+++ NHL  LP    SD +  S+L  +D+SSN+L  LP        +  + AS N L  L      TNW     L++   S N+LTELP   +     +  LN+SRN  +VF   W CPL     S N ++    K   FW   +K ++ + N L  +P  +  L  L  L+L  N L  LP  + W  ++L  LDLS NQ+      DG   L+T+ + +  T              E P    +++L+ L L  N LD +P ++C LK+L  L L +N GL  LPP+LG L N+W L+   L I NVP + +      +LS+LRA+LRK++    +K+++VG   +GK+TL+  +Q    P  +   +T+     +   P  ++    S     + F+VWD+ G       +QCF + K LY+VV+N+  G E + +L  WLLNI+A+APN+  ++VGTH+D +    + E +   R  ++            GFP I+      +S  S E  E LR++++    +M         Q   G+L P SYL L + ++ E  RR+       LT  ++ QL EQ  +NDI D+E+L +A  FL E G LLHF D   GL NL+F+DP WL + +  +  ++      + G I  ++L  +L      ++   QY + L +FEI L + +  +L+P +L   KP ++ H M H                T N + R + M +VP GFW RFIAR++I++ +  LQ+ ++     ++                             W++GL+VT++ GY  +ES    ++  KK  + G+ I   S+ +DFS M FI DH+  LI +W+P L      G  L+++ + CP+C    A    Q  D +  S    Y            F ++ C   AI+   I C +HPD PV L+ L+PE+ MTD P +  +    L+        LG GG+G V+Y  RY  + VA+KR H    K       A  P+D  +  L + D    +K+F E RQE  +L  LQH  IV  +G+   PLCF +E AP+ SL  +L +  + +    LG  LT  I +QI   + YLH  NII+ DLKS+N+LV SLD ++ IN+KLSDYGI+  +  +G  GV GTP +QAPEI+    YDEKVD+FSYG+ +YELL+G  P L +    +I K +  G+RP    +   + +   + LM ECW   P  RP +  + +  K     T +  L    Q + +      +T                 ++ W+ K+E+R + + + +   +       PG +VSC  QV+ ++W   E  ++    ++    +N+     + P V+  F      + +  ++    ++G++ VF  +        + +  H   R    I +ED  +RQ         P K M + N+ +E+W  +G  ++V++  + EI  RL        + + SV+C   G GE+ VW    K+  +  ++         Y+C    PL      R +  E     +    P + E D    V     EE+ T    +     D          P R   R                           H    AS  S  D      T      F++ + A++   V+ ++W+ R  GDVIVI
Sbjct:  156 MLALACQRGHLGVVKLLVLTHGADPESYAVRKNEFPVIVRLPLYAAIKSGNEDIAIFLLRHGAYFCSYILLDSPDPSKHLLRKYFIEASPLP-------SSYPGKTALRVKWSHLRLPWVDLDWLIDISCQITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPDPWACPLKCCKASRNALECLPDKMAVFWKNHLKDVDFSENALKEVPLGLFQLDALMFLRLQGNQLAALPPQEKWTCRQLKTLDLSRNQLGKN--EDG---LKTKRIAFFTTRGRQRSGTEAASVLEFPA-FLSESLEVLCLNDNHLDTVPPSVCLLKSLSELYLGNNPGLRELPPELGQLGNLWQLDTEDLTISNVPAEIQKEGPKAMLSYLRAQLRKAEKCKLMKMIIVGPPRQGKSTLLEILQTGRAPQVVHGEATIRTTKWELQRPAGSRAKVES-----VEFNVWDIGGPASMATVNQCFFTDKALYVVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCRSPSGSRATGFPDITFKHLHEISCKSLEGQEGLRQLIFHVTCSMKDVGSTIGCQRLAGRLIPRSYLSLQEAVLAEQQRRSRDDDVQYLTDRQLEQLVEQTPDNDIKDYEDLQSAISFLIETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIRAEDLRMLLVGTGFTQQTEEQYFQFLAKFEIALPVANDSYLLPHLLP-SKPGLDTHGMRH---------------PTANTIQRVFKMSFVPVGFWQRFIARMLISLAEMDLQLFENKKNTKSRNRKVTIYSFTGNQRNRCSTFRVKRNQTIYWQEGLLVTFDGGYLSVES---SDVNWKKKKSGGMKIVCQSEVRDFSAMAFITDHVNSLIDQWFPALTATESDGTPLMEQYVPCPVCETAWA----QHTDPSEKSEDVQY------------FDMEDCVLTAIERDFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHSEDEGSVLGQGGSGTVIYRARYQGQPVAVKRFHIKKFKNF-----ANVPADTMLRHLRATD---AMKNFSEFRQEASMLHALQHPCIVALIGISIHPLCFALELAPLSSLNTVLSENARDSSFIPLGHMLTQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSLDVKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRPALGHH-QLQIAKKLSKGIRPVL-GQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQMKDPTFATFMYELCCGKQTAFFSSQGQEYT-----------------VVFWDGKEESRNYTVVNTEKGLMEVQRMCCPGMKVSCQLQVQRSLWTATEDQKIYIYTLKGMCPLNTPQQALDTPAVVTCFLAVPVIKKNSYLVLAGLADGLVAVFPVVRGTPKDSCSYLCSHTANRSKFSIADED--ARQ------NPYPVKAMEVVNSGSEVWYSNGPGLLVIDCASLEICRRL--EPYMAPSMVTSVVCSSEGRGEEVVWCLDDKANSLVMYHSTTYQLCARYFCGVPSPLRDMFPVRPLDTEPPAASHT-ANPKVPEGDSIADVSIMYSEELGTQILIHQESLTDYCSMSSYSSSPPRQAARSPSSLPSSPASSSSVPFSTDCEDSDMLHTPGAASDRSEHD-----LTPMDGETFSQHLQAVKILAVRDLIWVPRRGGDVIVI 1931          
The following BLAST results are available for this feature:
BLAST of TCONS_00001134-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
LRRK10.000e+029.27Leucine-rich repeat serine/threonine-protein kinas... [more]
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