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TCONS_00001030-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00001030-protein
Unique NameTCONS_00001030-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length792

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00001030-protein ID=TCONS_00001030-protein|Name=TCONS_00001030-protein|organism=Clytia hemisphaerica|type=polypeptide|length=792bp
MAATSENNLSNIARISGGDLTREHRSLTIDNLNCGAEVDTGHFQSNGIRA
SQILSEAQNVEELFQLTSEQLQEMTNMYNTGNFAHPPSILFEEIEELKTK
LGTISKQRDEYSDAMKNGTAPPPVPPQQQTSTNSNNSDSDSQPSSPNLTR
STLNSFSDGSYNQSNGNSPHSSLRAHIRAFLPNNQRTMIKYKLGQTVREA
LYKAMSRRSLTTDSYRVYNKANRELIAWDSDVSLLDGAEVIVEMIDEEDP
STQNISHNFVRKTFFRLAFCDKCTKLLITGFRCTTCNYRFHQKCAQGIPP
LCEQAEHSQIYKRLLAKQNPNSNTNIPSTPRPISQRERSISAPNVNMIGQ
PDSGLIEAVLEKHYKNRTNQETATISGGLTRQMSSGPSSGRGRITNTLFT
PTSVSAPNSGENYFDFNTANSLPAPGNSKAQQISGIPDSLIHPARDRKNR
IRSSSEEHKKPRRRDSNDDWEIYADDLKIGERIGSGSYGTVYKGYWHGTV
AVKTLNVKDPNPQQLLAFQNEVGVLRKTRHVNVLLFMGCLSSPNLAIVTQ
WCEGSSLYRHLHVLEKKFPMHNLIEIARQTAQGIDYLHAKQIIHRDLKSN
NIFLQQDLTVKIGDFGLATVKTRWSGDHGCEQPSGSILWMAPEVIKMQDP
NPYTFFSDAYAFGICIYELITGSLPYCNIGNKDILIYRIGRGFIRPDQSK
IRSDCPKALKRLYLDCIKYNRDERPLFKQIVNSLETILMALPKITRSTSE
PILGRAKPSTDVEIAYPCPTPHTPIQGQDVFSFLSGQPQPVY
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000587XLOC_000587Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00001030TCONS_00001030Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR003116RBD_dom
IPR002219PE/DAG-bd
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR008271Ser/Thr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR029071Ubiquitin-rel_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0005057signal transducer activity, downstream of receptor
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007165signal transduction
GO:0035556intracellular signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007165 signal transduction
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0005057 signal transducer activity, downstream of receptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 94..114
NoneNo IPR availableGENE3D3.10.20.90coord: 177..243
e-value: 3.0E-16
score: 58.7
NoneNo IPR availableGENE3D1.10.510.10coord: 553..752
e-value: 2.5E-48
score: 164.0
NoneNo IPR availableGENE3D3.30.60.20coord: 250..314
e-value: 1.1E-12
score: 47.2
NoneNo IPR availableGENE3D3.30.200.20coord: 457..552
e-value: 4.7E-22
score: 77.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 105..171
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 422..466
NoneNo IPR availableCDDcd14062STKc_Rafcoord: 483..735
e-value: 0.0
score: 521.954
NoneNo IPR availableSUPERFAMILY57889Cysteine-rich domaincoord: 253..303
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 477..739
e-value: 6.4E-53
score: 191.8
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 477..738
score: 40.725
IPR003116Raf-like Ras-bindingSMARTSM00455RBD_5coord: 175..245
e-value: 2.7E-11
score: 53.5
IPR003116Raf-like Ras-bindingPFAMPF02196RBDcoord: 177..243
e-value: 9.6E-18
score: 63.9
IPR003116Raf-like Ras-bindingPROSITEPS50898RBDcoord: 175..245
score: 21.875
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainSMARTSM00109c1_12coord: 257..302
e-value: 1.0E-9
score: 48.3
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainPFAMPF00130C1_1coord: 257..304
e-value: 1.4E-11
score: 44.0
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainPROSITEPS00479ZF_DAG_PE_1coord: 257..302
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainPROSITEPS50081ZF_DAG_PE_2coord: 256..302
score: 13.558
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainCDDcd00029C1coord: 257..302
e-value: 6.35895E-13
score: 63.6652
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 477..734
e-value: 4.5E-57
score: 193.2
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 592..604
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 483..503
IPR029071Ubiquitin-related domainSUPERFAMILY54236Ubiquitin-likecoord: 176..244
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 464..755

Blast
BLAST of TCONS_00001030-protein vs. Swiss-Prot (Human)
Match: BRAF (Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4)

HSP 1 Score: 600.512 bits (1547), Expect = 0.000e+0
Identity = 350/782 (44.76%), Postives = 463/782 (59.21%), Query Frame = 0
Query:   53 ILSEAQNVEELFQLTSEQLQEMTNMYNTGNFAHPPSILFEEIEELKTKLGTISKQRDEYSDAMKNGTAPPPVPPQQQTSTNSNNSDSDSQPSSPNLTRSTLNSFSDGS-YNQSNGNSPHSSLRAHIRAFLPNNQRTMIKYKLGQTVREALYKAMSRRSLTTDSYRVY--NKANRELIAWDSDVSLLDGAEVIVEMIDEEDPSTQNISHNFVRKTFFRLAFCDKCTKLLITGFRCTTCNYRFHQKCAQGIPPLC----------------------EQAEHSQ----------------IYKRLLAKQNPNSNTNIPSTPRP--------ISQRERSISAPNVNMIGQPDSGLIEAVLEKHYKNRTNQETATISGGLTRQMSSGP-SSGRGRITNTLFTPTSVSAPNSGENYFDFNTANSLPAPGNSKAQQISGIPDSLIHPARDRKNRIRSSSEEHKKPR-RRDSNDDWEIYADDLKIGERIGSGSYGTVYKGYWHGTVAVKTLNVKDPNPQQLLAFQNEVGVLRKTRHVNVLLFMGCLSSPNLAIVTQWCEGSSLYRHLHVLEKKFPMHNLIEIARQTAQGIDYLHAKQIIHRDLKSNNIFLQQDLTVKIGDFGLATVKTRWSGDHGCEQPSGSILWMAPEVIKMQDPNPYTFFSDAYAFGICIYELITGSLPYCNIGNKDILIYRIGRGFIRPDQSKIRSDCPKALKRLYLDCIKYNRDERPLFKQIVNSLETILMALPKITRSTSEPILGRAKPSTDVEIAYPCPTPHTPIQGQDVFSF 783
            I  E  N++++ +LT E ++ + + +  G   +PPSI  E  EE  +KL  + ++  +  +++ NGT          +S+ S ++ + S  SS ++  S+L+ F + +   +SN  SP   +   +R FLPN QRT++  + G TVR++L KA+  R L  +   VY      ++ I WD+D+S L G E+ VE++ E  P T   +HNFVRKTFF LAFCD C KLL  GFRC TC Y+FHQ+C+  +P +C                      E+A  ++                I  ++L   +P+ +  IP   RP          QR+RS SAPNV++       + + + ++ ++           GG T  +S+ P +S  G +TN                                KA Q S        P R+RK+   S      K   RRDS+DDWEI    + +G+RIGSGS+GTVYKG WHG VAVK LNV  P PQQL AF+NEVGVLRKTRHVN+LLFMG  + P LAIVTQWCEGSSLY HLH++E KF M  LI+IARQTAQG+DYLHAK IIHRDLKSNNIFL +DLTVKIGDFGLATVK+RWSG H  EQ SGSILWMAPEVI+MQD NPY+F SD YAFGI +YEL+TG LPY NI N+D +I+ +GRG++ PD SK+RS+CPKA+KRL  +C+K  RDERPLF QI+ S+E +  +LPKI RS SEP L RA   T+    Y C +P TPIQ     +F
Sbjct:   43 IPEEVWNIKQMIKLTQEHIEALLDKF--GGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTD------FSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPI---VRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVL-ENVPLT---THNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRG---------DGGSTTGLSATPPASLPGSLTNV-------------------------------KALQKSP------GPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAF 763          
The following BLAST results are available for this feature:
BLAST of TCONS_00001030-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
BRAF0.000e+044.76Serine/threonine-protein kinase B-raf OS=Homo sapi... [more]
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