TCONS_00000718-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00000718-protein
Unique NameTCONS_00000718-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length482

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00000718-protein ID=TCONS_00000718-protein|Name=TCONS_00000718-protein|organism=Clytia hemisphaerica|type=polypeptide|length=482bp
MDSLERHANIYQNDNTGSFERAVRVVTAFYPPFVKQVSPDISNVTGDYKC
GQAKLCEVPKKNQNGTVTWTVSCCTGYIVDSFEMVQRKLNFEYTLYIVED
GKWGTLENETWNGMIGDLVDKKADLIINIMTPLEIRAKDIHFTHHFMESN
FGIVRVKEYNSDIPSFDFLKPVGGNLHFAILASTILTLLTISFLENYFLK
FTKKQGVFFQETMAYVFGLTFQRDMGGTNPRMWSGRLTALGYASAMTIIM
SVYTARITANSIGQVVMDDFKGFKDKKFQNPSEDYKFTLVGGQGWAIESF
FRDHPDESFQRMYKFMSKYFVKTEIEGVKKLLDGTIQAYIADSGSFPVVL
QRITSELGCPKEIELLEESFIGTHGLSFAYRKNFPYGKTISNTLLGLYQT
GALIRLRKKWFPSSHCKGKTPVQQFDWTYFSGILVIVGYTVIIGIFVNLI
EHFYMFLRKMYKSKSADLTEQKRSTKYTETNI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000452XLOC_000452Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00000718TCONS_00000718Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001508Iono_rcpt_met
IPR001320Iontro_rcpt
IPR019594Glu/Gly-bd
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0004872receptor activity
GO:0004970ionotropic glutamate receptor activity
GO:0005234extracellular-glutamate-gated ion channel activity
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016020 membrane
molecular_function GO:0005234 extracellular-glutamate-gated ion channel activity
molecular_function GO:0005216 ion channel activity
molecular_function GO:0004970 ionotropic glutamate receptor activity
molecular_function GO:0004872 receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001508Ionotropic glutamate receptor, metazoaPRINTSPR00177NMDARECEPTORcoord: 237..264
score: 25.0
coord: 91..119
score: 30.34
coord: 430..454
score: 31.6
IPR001320Ionotropic glutamate receptorSMARTSM00079GluR_14coord: 66..413
e-value: 1.4E-7
score: 14.9
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domainSMARTSM00918Lig_chan_Glu_bd_2coord: 65..120
e-value: 2.3E-12
score: 57.1
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domainPFAMPF10613Lig_chan-Glu_bdcoord: 72..155
e-value: 1.3E-20
score: 73.6
NoneNo IPR availableGENE3D3.40.190.10coord: 261..356
e-value: 1.0E-9
score: 38.2
NoneNo IPR availableGENE3D3.40.190.10coord: 19..162
e-value: 1.9E-22
score: 78.8
NoneNo IPR availableSUPERFAMILY53850Periplasmic binding protein-like IIcoord: 274..415
coord: 23..158

Blast
BLAST of TCONS_00000718-protein vs. Swiss-Prot (Human)
Match: NMD3A (Glutamate receptor ionotropic, NMDA 3A OS=Homo sapiens GN=GRIN3A PE=1 SV=2)

HSP 1 Score: 144.436 bits (363), Expect = 8.490e-37
Identity = 121/492 (24.59%), Postives = 210/492 (42.68%), Query Frame = 0
Query:    2 DSLERHANIYQNDNTGSFERAVRVVTAFYPPFVKQVSPDISNVTGDYKCGQAKLCEVPKKNQNGTVTWTVS---------------CCTGYIVDSFEMVQRKLNFEYTLYIVEDGKWGTLENETWNGMIGDLVDKKADLIINIMTPLEIRAKDIHFTHHFMESNFGIVRVKEYNSDIPSFDFLKPVGGNLHFAILASTILTLLTISFLE-----NYFLKFTKKQGVF-FQETMAYVFGLTFQRDMGGTNPRMWSGRLTALGYASAMTIIMSVYTARITANSIGQVVMDDFKGFKDKKFQNPSEDYKFTLVGGQGWAIESFFRDHPDESFQRMYKFMSKYFVKTEIEGVKKLLDGT--IQAYIADSGSFPVVLQRITSELGCPKEIELLEESFIGTHGLSFAYRKNFPYGKTISNTLLGLYQTGALIRLRKKWFPSSHCKGK----TPVQQFDWTYFSGILVIVGYTVIIGIFVNLIEHF-YMFLRKMYKSKS 465
            +  +RH   +Q+ +    +  +RVVT    PFV         V  +  C   +LC  P  N + T+    S               CC GY +D  E +   +NF++ LYIV DGK+G  +N  W G++GDL+   A + +   +    R++ I FT  F  ++ GI+ V+  ++  P   F+ P+   +   I  +  +T + ++  E         K   +  VF F   +   + L F R +    P+ W+GR     +A      +S YTA + A  +G+ + ++  G  D K  +PS+ ++F      G   ES   D+  +SF  M+++M +Y V    +GV+ L +    + A+I D     ++   ++ +  C  ++  + + F    G       N P    IS  +      G +  L  KW+    C  +    T   Q    +FSG+ V++     + I   + EH  Y  L    K+KS
Sbjct:  498 EQAQRHKTHFQHPS----KLHLRVVTLIEHPFVF-----TREVDDEGLCPAGQLCLDPMTNDSSTLDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEKIAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLRGTAHMAVTSFSINTARSQVIDFTSPFFSTSLGIL-VRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAVFLTLYEWKSPFGLTPKGRNRSKVFSFSSALNICYALLFGRTVAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRF------GTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVEYLKNDPEKLDAFIMDKA---LLDYEVSIDADC--KLLTVGKPF-AIEGYGIGLPPNSPLTANISELISQYKSHGFMDMLHDKWYRVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKS 967          
The following BLAST results are available for this feature:
BLAST of TCONS_00000718-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NMD3A8.490e-3724.59Glutamate receptor ionotropic, NMDA 3A OS=Homo sap... [more]
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