TCONS_00000609-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00000609-protein
Unique Name	TCONS_00000609-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	556

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00000609-protein ID=TCONS_00000609-protein|Name=TCONS_00000609-protein|organism=Clytia hemisphaerica|type=polypeptide|length=556bp
MWRTTKQFINNYVYKLKLNKIERSNVLLLYTIAIILINTNTILGIQDNHV
MSINNNSSATDHMRELSKDNGTITPLANHNVTHSLKWHVNHERMLWQNKC
TEYDWSIEKGCNISALLQKLLKGYDKRLRPLMDFQEPVMVTVGFWILSID
SINVIDMDYQIDFFFRQSWTDERLKHSYPQTLTLSNSMLDKLWVPDTYFE
NSKNSQFHSVTVPNKMLKIKPDGTVLYNARISVRASCPMDLRMFPMDSQE
CNLNIESYGYSVYDIRFQWEEDKQKRLSIGTKVRTLPQYNLTQFDTANST
EAYVVGNYSRLTAIFVLQRRTGYFFLHLYAPCALIVMISWISFCIPKDST
AARVALGITSVLTITTILNMLNTAMPKVSYIKAVDWYLIVSFLFVFAVLI
EYTLVLYLTDKEKQTQEENKNKFKKKRPPNMDKQFVGANGHVIDRNNHHE
LRSRAYQNNNYKENHYDCSDGEFQTKPLIVVLEEKNLRNHRQNHHHHTRA
HNDDDHSAALQSHTGKFLCEFRVDVIDEYSRMIFPLAFIIFNIVYWLLFY
SKKNEK

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_000357	XLOC_000357	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00000609	TCONS_00000609	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006028	GABAA/Glycine_rcpt
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha	PRINTS	PR00253	GABAARECEPTR	coord: 350..371 score: 49.72 coord: 529..549 score: 51.16 coord: 324..344 score: 43.78 coord: 384..405 score: 44.25
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 315..327 score: 31.05 coord: 160..176 score: 37.8 coord: 237..251 score: 52.97 coord: 191..202 score: 46.91
IPR006201	Neurotransmitter-gated ion-channel	TIGRFAM	TIGR00860	TIGR00860	coord: 114..548 e-value: 3.9E-119 score: 396.3
None	No IPR available	GENE3D	1.20.58.390		coord: 327..556 e-value: 2.0E-51 score: 173.6
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 99..326 e-value: 3.4E-63 score: 212.6
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 115..321 e-value: 3.0E-49 score: 167.3
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 114..320
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 328..546 e-value: 3.2E-35 score: 122.2
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 321..550
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 237..251

Blast

[Close]

BLAST of TCONS_00000609-protein vs. Swiss-Prot (Human)
Match: GBRB1 (Gamma-aminobutyric acid receptor subunit beta-1 OS=Homo sapiens GN=GABRB1 PE=1 SV=2)

HSP 1 Score: 300.056 bits (767), Expect = 6.503e-96
Identity = 173/451 (38.36%), Postives = 246/451 (54.55%), Query Frame = 0

Query:  117 LQKLLKGYDKRLRPLMDFQ-EPVMVTVGFWILSIDSINVIDMDYQIDFFFRQSWTDERLKHS-YPQTLTLSNSMLDKLWVPDTYFENSKNSQFHSVTVPNKMLKIKPDGTVLYNARISVRASCPMDLRMFPMDSQECNLNIESYGYSVYDIRFQWEEDKQKRLSIGTKVRTLPQYNLTQFDTANSTEAYVVGNYSRLTAIFVLQRRTGYFFLHLYAPCALIVMISWISFCIPKDSTAARVALGITSVLTITTILNMLNTAMPKVSYIKAVDWYLIVSFLFVFAVLIEYTLVLYL---TDKEKQTQEENKNKFKKKRPPNMDKQFVGANGHV----IDRNNHHELRSRAYQNNNYKENHYDCSDGEFQ-TKPLIVVLEEKNLRNHRQNHHHHTRAHNDDDHSAALQSHTGKFLCEFRVDV--------IDEYSRMIFPLAFIIFNIVYWLLF 549
            + +LLKGYD RLRP  DF   PV V +   + SID ++ ++MDY +  +F+QSW D+RL +S  P  LTL N + D+LWVPDTYF N K S  H VTV N+M+++ PDGTVLY  RI+  A+C MDLR +P+D Q C L IESYGY+  DI F W   +      G     LPQ+++  +   +    +  G Y RL+  F L+R  GYF L  Y P  LI ++SW+SF I  D++AARVALGIT+VLT+TTI   L   +PK+ Y+KA+D YL+  F+FVF  L+EY  V Y+      +K+   +      +K    M+K  V A+G++    ++  N           ++ K   Y       Q  KPL              +   + RA   D H    +    +   + +V +        ID++SRM FP+ F +FN+VYWL +
Sbjct:   41 VDRLLKGYDIRLRP--DFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGA--VTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPL-------------SSREAYGRAL--DRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472

The following BLAST results are available for this feature:

BLAST of TCONS_00000609-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00000609-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
GBRB1	6.503e-96	38.36	Gamma-aminobutyric acid receptor subunit beta-1 OS...	[more]

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TCONS_00000609-protein (polypeptide) - C. hemisphaerica