TCONS_00000567-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00000567-protein
Unique Name	TCONS_00000567-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	973

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00000567-protein ID=TCONS_00000567-protein|Name=TCONS_00000567-protein|organism=Clytia hemisphaerica|type=polypeptide|length=973bp
MFSIKMTHRCSCILFCLYLMITSVKSVEKVLTYKVNTKTDSIWEYDDIDA
DGCEKIKYKRGFQLFCVDARFSCTLKSKPLILDEFKSEFFNITIENSLGG
SDPCVSCSGEISGTVDLFQTYKKDSDGKIDSTRSHNFALAESVTKTIQKK
PNLEYIEIWLTLSRICKQSLIVKLSSAACKPVESIKNLIDVPKDQVFPAP
SKEQETNDVGLSCVDNAVVKEEPVLKCMADASYQITGSCQCNVSYEKFED
RCQKCSANSFKLDIGNGKCEQCKANSNYSEALQMCVCQGDYLRALDEKTN
RNAPCYKKPVMLFSKDIYILNNKNTSVTIQMLDYGPSTTYIINLPHNVRK
VANKPIFKIDHLRPNSQYNITIEVQNDVLSAIGVEIKVTKSFWTNVKKPG
AVKNIRLERETILIWDPITDAGPVEYVIEMQNETLTTPNNFHSLENNMKF
VSGKIHAEVNGPTGKIKGYPIAFTFTPTTPKEKNDFHLIIGGSVGGFLLI
LIILMIALLVKKHRKPAQFEVTRMEDGTMTIPRMTLFKTSRLYVDPTTYS
HVDEAVEEFALELDRSCLTMDQLIGGGEFANVFKGILSTESRNSDVAIKV
LKSGANRSDRDDFLSEAAILGQFSDPNVVSIEGVVLKDYPSLIVLEYMAN
GSLDKYLVKNDSQFSVAKLLGMARGVASGMKYLSDLGFIHRDLAARNVLV
NSEDCCKIADFGMSRELKTDDTYDTKGGKIPIKWTAPEAIEYKKFTTASD
VWSYGIVCWEIFSYGERPYWEWSNYEVMERLSTGYRLPPPMECPKGIHDL
MLQCWHKDRLKRPRFSNILQKVEEWLKNPDRLTDIASVITKRDENLDYSV
LDDLASWLEAINMKQYLKMFTESGYMTPKDILYLTNEDLESLGVGLIGHR
KKLLKAIKNTKNQTESTNKSDTDSKASKVSRTSSFAGFGSSLSKKVSFLA
SPNSSISFKKTVGKRTSLGYQLQ

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_000336	XLOC_000336	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00000567	TCONS_00000567	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR020635	Tyr_kinase_cat_dom
IPR001660	SAM
IPR027936	Eph_TM
IPR013783	Ig-like_fold
IPR008266	Tyr_kinase_AS
IPR017441	Protein_kinase_ATP_BS
IPR000719	Prot_kinase_dom
IPR013761	SAM/pointed
IPR011009	Kinase-like_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding

Vocabulary: **Biological Process**
Term	Definition
GO:0006468	protein phosphorylation

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006468	protein phosphorylation
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0005515	protein binding
molecular_function	GO:0004672	protein kinase activity
molecular_function	GO:0004713	protein tyrosine kinase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PRINTS	PR00109	TYRKINASE	coord: 749..771 score: 57.67 coord: 645..658 score: 45.26 coord: 730..740 score: 68.1 coord: 793..815 score: 44.72 coord: 682..700 score: 64.93
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 568..821 e-value: 2.7E-92 score: 308.6
IPR020635	Tyrosine-protein kinase, catalytic domain	SMART	SM00219	tyrkin_6	coord: 568..822 e-value: 7.3E-131 score: 450.7
IPR001660	Sterile alpha motif domain	SMART	SM00454	SAM_4	coord: 846..913 e-value: 2.7E-14 score: 63.5
IPR001660	Sterile alpha motif domain	PFAM	PF00536	SAM_1	coord: 852..909 e-value: 5.7E-16 score: 58.6
IPR001660	Sterile alpha motif domain	PROSITE	PS50105	SAM_DOMAIN	coord: 849..913 score: 18.503
IPR027936	Ephrin receptor, transmembrane domain	PFAM	PF14575	EphA2_TM	coord: 489..564 e-value: 4.3E-10 score: 40.2
IPR013783	Immunoglobulin-like fold	GENE3D	2.60.40.10		coord: 315..487 e-value: 6.9E-5 score: 22.2
None	No IPR available	GENE3D	1.10.150.50		coord: 846..909 e-value: 7.5E-17 score: 60.8
None	No IPR available	GENE3D	1.10.510.10		coord: 645..828 e-value: 7.1E-49 score: 165.1
None	No IPR available	GENE3D	3.30.200.20		coord: 549..644 e-value: 7.2E-21 score: 73.6
IPR008266	Tyrosine-protein kinase, active site	PROSITE	PS00109	PROTEIN_KINASE_TYR	coord: 688..700
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 574..599
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 568..826 score: 37.107
IPR013761	Sterile alpha motif/pointed domain	SUPERFAMILY	47769	SAM/Pointed domain	coord: 846..915
IPR011009	Protein kinase-like domain	SUPERFAMILY	56112	Protein kinase-like (PK-like)	coord: 561..840

Blast

[Close]

BLAST of TCONS_00000567-protein vs. Swiss-Prot (Human)
Match: EPHB2 (Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2 PE=1 SV=5)

HSP 1 Score: 449.899 bits (1156), Expect = 1.010e-141
Identity = 290/798 (36.34%), Postives = 422/798 (52.88%), Query Frame = 0

Query:  212 SCVDNAVVKEEPV-LKCMADASYQI-TGSCQCNVSYEKFEDR--CQKCSANSFKLDIGNGKCEQCKANS-NYSEALQMCVCQGDYLRA-LDEKTNRNAPCYKKPVMLFSKDIYILNNKNTSVTIQMLDYGPST--------TYII-----------------NLPHNVRKVA-NKPIFKIDHLRPNSQYNITIEVQNDV-----LSAIGVEIKVTKSFWTNVKKPGAVKNIRLERETI----LIWDPITDAGPVEYVIEMQ---------NET-LTTPNN---FHSLENNMKFVSGKIHAEVNGPTGKIKGYPIAFTFTP----TTPKEKNDFHLIIGGSVGGFLLILIILMIALLVKKH---RKPAQF--EVTRMEDGTMTIPRMTLFKTSRLYVDPTTYSHVDEAVEEFALELDRSCLTMDQLIGGGEFANVFKGILSTES-RNSDVAIKVLKSGANRSDRDDFLSEAAILGQFSDPNVVSIEGVVLKDYPSLIVLEYMANGSLDKYLVKNDSQFSVAKLLGMARGVASGMKYLSDLGFIHRDLAARNVLVNSEDCCKIADFGMSRELK---TDDTYDTK-GGKIPIKWTAPEAIEYKKFTTASDVWSYGIVCWEIFSYGERPYWEWSNYEVMERLSTGYRLPPPMECPKGIHDLMLQCWHKDRLKRPRFSNILQKVEEWLKNPDRLTDIASVITKRDENL------DYSVLDDLASWLEAINMKQYLKMFTESGYMTPKDILYLTNEDLESLGVGLIGHRKKLLKAIKNTK---NQTESTNKSDTDSKASKVSRT 932
            SC+ NA   + P+ L C  D  + +  G C C   +E  E+   C+ C + +FK + G+  C  C  NS   SE    CVC+  Y RA LD     + PC   P    S    ++++ N   T  ML++ P           Y I                 N+ +  R++   +P   I  L  ++QY   I+  N V      S     + +T    TN   P AV  +     T+    L W        V    E+Q         N T + +P N      L+    +V  ++ A      G+  G     T T     T+ +EK    LIIG S  G + ++ +++IA++  +    R  +++  ++     G MT P M      ++Y+DP TY   +EAV EFA E+D SC+ ++Q+IG GEF  V  G L     R   VAIK LKSG     R DFLSEA+I+GQF  PNV+ +EGVV K  P +I+ E+M NGSLD +L +ND QF+V +L+GM RG+A+GMKYL+D+ ++HRDLAARN+LVNS   CK++DFG+SR L+   +D TY +  GGKIPI+WTAPEAI+Y+KFT+ASDVWSYGIV WE+ SYGERPYW+ +N +V+  +   YRLPPPM+CP  +H LML CW KDR  RP+F  I+  +++ ++NP+ L  +A + +  +  L      DY+  + +  WLEAI M QY + F  +G+ +   +  +  ED+  +GV L GH+KK+L +I+  +   NQ +S        +     RT
Sbjct:  225 SCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDP---LDMPCTTIP----SAPQAVISSVNE--TSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNIT----TNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVF-QVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK--LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMT-PGM------KIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEGQPLARRPRATGRT 999

The following BLAST results are available for this feature:

BLAST of TCONS_00000567-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00000567-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
EPHB2	1.010e-141	36.34	Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2 ...	[more]

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TCONS_00000567-protein (polypeptide) - C. hemisphaerica

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