TCONS_00000567-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00000567-protein
Unique NameTCONS_00000567-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length973

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00000567-protein ID=TCONS_00000567-protein|Name=TCONS_00000567-protein|organism=Clytia hemisphaerica|type=polypeptide|length=973bp
MFSIKMTHRCSCILFCLYLMITSVKSVEKVLTYKVNTKTDSIWEYDDIDA
DGCEKIKYKRGFQLFCVDARFSCTLKSKPLILDEFKSEFFNITIENSLGG
SDPCVSCSGEISGTVDLFQTYKKDSDGKIDSTRSHNFALAESVTKTIQKK
PNLEYIEIWLTLSRICKQSLIVKLSSAACKPVESIKNLIDVPKDQVFPAP
SKEQETNDVGLSCVDNAVVKEEPVLKCMADASYQITGSCQCNVSYEKFED
RCQKCSANSFKLDIGNGKCEQCKANSNYSEALQMCVCQGDYLRALDEKTN
RNAPCYKKPVMLFSKDIYILNNKNTSVTIQMLDYGPSTTYIINLPHNVRK
VANKPIFKIDHLRPNSQYNITIEVQNDVLSAIGVEIKVTKSFWTNVKKPG
AVKNIRLERETILIWDPITDAGPVEYVIEMQNETLTTPNNFHSLENNMKF
VSGKIHAEVNGPTGKIKGYPIAFTFTPTTPKEKNDFHLIIGGSVGGFLLI
LIILMIALLVKKHRKPAQFEVTRMEDGTMTIPRMTLFKTSRLYVDPTTYS
HVDEAVEEFALELDRSCLTMDQLIGGGEFANVFKGILSTESRNSDVAIKV
LKSGANRSDRDDFLSEAAILGQFSDPNVVSIEGVVLKDYPSLIVLEYMAN
GSLDKYLVKNDSQFSVAKLLGMARGVASGMKYLSDLGFIHRDLAARNVLV
NSEDCCKIADFGMSRELKTDDTYDTKGGKIPIKWTAPEAIEYKKFTTASD
VWSYGIVCWEIFSYGERPYWEWSNYEVMERLSTGYRLPPPMECPKGIHDL
MLQCWHKDRLKRPRFSNILQKVEEWLKNPDRLTDIASVITKRDENLDYSV
LDDLASWLEAINMKQYLKMFTESGYMTPKDILYLTNEDLESLGVGLIGHR
KKLLKAIKNTKNQTESTNKSDTDSKASKVSRTSSFAGFGSSLSKKVSFLA
SPNSSISFKKTVGKRTSLGYQLQ
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000336XLOC_000336Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00000567TCONS_00000567Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR001660SAM
IPR027936Eph_TM
IPR013783Ig-like_fold
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR000719Prot_kinase_dom
IPR013761SAM/pointed
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005515protein binding
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 749..771
score: 57.67
coord: 645..658
score: 45.26
coord: 730..740
score: 68.1
coord: 793..815
score: 44.72
coord: 682..700
score: 64.93
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 568..821
e-value: 2.7E-92
score: 308.6
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 568..822
e-value: 7.3E-131
score: 450.7
IPR001660Sterile alpha motif domainSMARTSM00454SAM_4coord: 846..913
e-value: 2.7E-14
score: 63.5
IPR001660Sterile alpha motif domainPFAMPF00536SAM_1coord: 852..909
e-value: 5.7E-16
score: 58.6
IPR001660Sterile alpha motif domainPROSITEPS50105SAM_DOMAINcoord: 849..913
score: 18.503
IPR027936Ephrin receptor, transmembrane domainPFAMPF14575EphA2_TMcoord: 489..564
e-value: 4.3E-10
score: 40.2
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 315..487
e-value: 6.9E-5
score: 22.2
NoneNo IPR availableGENE3D1.10.150.50coord: 846..909
e-value: 7.5E-17
score: 60.8
NoneNo IPR availableGENE3D1.10.510.10coord: 645..828
e-value: 7.1E-49
score: 165.1
NoneNo IPR availableGENE3D3.30.200.20coord: 549..644
e-value: 7.2E-21
score: 73.6
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 688..700
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 574..599
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 568..826
score: 37.107
IPR013761Sterile alpha motif/pointed domainSUPERFAMILY47769SAM/Pointed domaincoord: 846..915
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 561..840

Blast
[Close]
BLAST of TCONS_00000567-protein vs. Swiss-Prot (Human)
Match: EPHB2 (Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2 PE=1 SV=5)

HSP 1 Score: 449.899 bits (1156), Expect = 1.010e-141
Identity = 290/798 (36.34%), Postives = 422/798 (52.88%), Query Frame = 0 
Query:  212 SCVDNAVVKEEPV-LKCMADASYQI-TGSCQCNVSYEKFEDR--CQKCSANSFKLDIGNGKCEQCKANS-NYSEALQMCVCQGDYLRA-LDEKTNRNAPCYKKPVMLFSKDIYILNNKNTSVTIQMLDYGPST--------TYII-----------------NLPHNVRKVA-NKPIFKIDHLRPNSQYNITIEVQNDV-----LSAIGVEIKVTKSFWTNVKKPGAVKNIRLERETI----LIWDPITDAGPVEYVIEMQ---------NET-LTTPNN---FHSLENNMKFVSGKIHAEVNGPTGKIKGYPIAFTFTP----TTPKEKNDFHLIIGGSVGGFLLILIILMIALLVKKH---RKPAQF--EVTRMEDGTMTIPRMTLFKTSRLYVDPTTYSHVDEAVEEFALELDRSCLTMDQLIGGGEFANVFKGILSTES-RNSDVAIKVLKSGANRSDRDDFLSEAAILGQFSDPNVVSIEGVVLKDYPSLIVLEYMANGSLDKYLVKNDSQFSVAKLLGMARGVASGMKYLSDLGFIHRDLAARNVLVNSEDCCKIADFGMSRELK---TDDTYDTK-GGKIPIKWTAPEAIEYKKFTTASDVWSYGIVCWEIFSYGERPYWEWSNYEVMERLSTGYRLPPPMECPKGIHDLMLQCWHKDRLKRPRFSNILQKVEEWLKNPDRLTDIASVITKRDENL------DYSVLDDLASWLEAINMKQYLKMFTESGYMTPKDILYLTNEDLESLGVGLIGHRKKLLKAIKNTK---NQTESTNKSDTDSKASKVSRT 932
            SC+ NA   + P+ L C  D  + +  G C C   +E  E+   C+ C + +FK + G+  C  C  NS   SE    CVC+  Y RA LD     + PC   P    S    ++++ N   T  ML++ P           Y I                 N+ +  R++   +P   I  L  ++QY   I+  N V      S     + +T    TN   P AV  +     T+    L W        V    E+Q         N T + +P N      L+    +V  ++ A      G+  G     T T     T+ +EK    LIIG S  G + ++ +++IA++  +    R  +++  ++     G MT P M      ++Y+DP TY   +EAV EFA E+D SC+ ++Q+IG GEF  V  G L     R   VAIK LKSG     R DFLSEA+I+GQF  PNV+ +EGVV K  P +I+ E+M NGSLD +L +ND QF+V +L+GM RG+A+GMKYL+D+ ++HRDLAARN+LVNS   CK++DFG+SR L+   +D TY +  GGKIPI+WTAPEAI+Y+KFT+ASDVWSYGIV WE+ SYGERPYW+ +N +V+  +   YRLPPPM+CP  +H LML CW KDR  RP+F  I+  +++ ++NP+ L  +A + +  +  L      DY+  + +  WLEAI M QY + F  +G+ +   +  +  ED+  +GV L GH+KK+L +I+  +   NQ +S        +     RT
Sbjct:  225 SCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDP---LDMPCTTIP----SAPQAVISSVNE--TSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNIT----TNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVF-QVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK--LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMT-PGM------KIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEGQPLARRPRATGRT 999
The following BLAST results are available for this feature:
BLAST of TCONS_00000567-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
EPHB21.010e-14136.34Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2 ... [more]
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