TCONS_00000215-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00000215-protein
Unique NameTCONS_00000215-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length950

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00000215-protein ID=TCONS_00000215-protein|Name=TCONS_00000215-protein|organism=Clytia hemisphaerica|type=polypeptide|length=950bp
MVCYRKFIKYLYPKPRRKTMVVLSLIAIVFIFFSVQRTTHRKHIKNTLWV
SHQNLSPDTWQGDTNFGGSFNSIENKDETKQKVEPEVEFVPKSRFESMEN
VYNITFEPSRSVLVFTGSETSNTKDQLKALFRSMKIVFDFLTWNKMDDNY
LTMPRFIDKYGHTRYQTFIFTDENIYDDFDGYNWELVKRHCQRFNIGIII
LCHPVHTETIKTKQLTSLPLTLIYGVNNLKTAEIPSNDVLKLVKSPNVLK
GDLPGKRHVLFHSKHPTFKTLMMTDSAFTGGRKRRDTGQQDLINFNEKHT
LYSISKSAIALYDQGLFDGVRKFIFGVSFWESWLYQLVLMDCLQLSSNGF
LGNDLQRYIQIDVDDIFVGKTGKRLVKEDVQAMIEAQEYLSTKITNFKFN
IGYSGQRYQLSNDSREREGDAYLMQSDVHKHFRWFCHTSNHIKPHQFSRD
ELIKDFEWNKKFAERFGLDVDHTYAVAPHHSGVYPVHDALYKAWQSVYGI
QVTSTEGYPHLKPAYGRKGFLYEDIMVLPRQTCGLFTKTLSAATHPKGPT
YLYDMTQGGELFWTILFNPILIFMTHMNNYGMKERLALSVFKNVTDFVDR
WTNLRMQSIPPVEMANKYFELFPKQIEPLWTDPCDDLRHQLIWNHTNKYC
IPDKRSTISRLPDVLILGPQKTGTTALLTFLAIHPDIVTSVRSNHSFEEI
QFFNKRNYKFGLDWYLNFFPETRKSKDLVYIDKSANYFDSLKAPLRASSF
LPQAKLVVILIDPRLRAYSWFQHMRSKSPMVPYPHTFYEVISTKNLTNDH
EFDMLTAKCLLPGRYAESIERWLQYYDSSKLLVLDGDELKHKPIMTMSKV
QTFLRLSPYPFHKHITYSSKKKYFCRFFHNKHYCLGKGKGRDYGKMTGKE
WQFLSNYYHLPNLKLYDLLKKLGKIIPVWLQKEIDLVQNNKHKRRRRRSV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000118XLOC_000118Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00000215TCONS_00000215Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR021930Heparan_SO4_deacetylase
IPR000863Sulfotransferase_dom
IPR027417P-loop_NTPase
Vocabulary: Molecular Function
TermDefinition
GO:0016787hydrolase activity
GO:0015016[heparan sulfate]-glucosamine N-sulfotransferase activity
GO:0008146sulfotransferase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity
molecular_function GO:0016787 hydrolase activity
molecular_function GO:0008146 sulfotransferase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR021930Heparan sulphate-N-deacetylasePFAMPF12062HSNSDcoord: 93..562
e-value: 1.1E-110
score: 370.6
NoneNo IPR availableGENE3D3.40.50.300coord: 627..938
e-value: 1.0E-55
score: 188.7
IPR000863Sulfotransferase domainPFAMPF00685Sulfotransfer_1coord: 662..880
e-value: 5.6E-30
score: 104.6
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 629..933

Blast
BLAST of TCONS_00000215-protein vs. Swiss-Prot (Human)
Match: NDST4 (Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 OS=Homo sapiens GN=NDST4 PE=2 SV=1)

HSP 1 Score: 642.114 bits (1655), Expect = 0.000e+0
Identity = 347/834 (41.61%), Postives = 503/834 (60.31%), Query Frame = 0
Query:  111 SVLVFTGSETSNTKDQLKALFRSMKIVFDFLTWNKMDDNYLTMPRFIDKYGHTRYQTFIFTDENIYDDFDGYNWELVKRHCQRFNIGIIILCHPVHTETIKTKQLTSLPLTLIYGVNNLKTAEI---PSNDVLKLVKSPNVLKGDLPGKRHVLFHSKHPTFKTLMMTDSAFTGGRKRRDTGQQDLINFNEKHTLYSISKSAIALYDQGLFDGVRKFIFGVSFWESWLYQLVLMDCLQLSSNGFLGNDLQRYIQIDVDDIFVGKTGKRLVKEDVQAMIEAQEYLSTKITNFKFNIGYSGQRYQLSNDSREREGDAYLMQSDVHKHFRWFCHTSNHIKPHQF-SRDELIKDFEWNKKFAERFGLDVDHTYAVAPHHSGVYPVHDALYKAWQSVYGIQVTSTEGYPHLKPAYGRKGFLYEDIMVLPRQTCGLFTKTLSAATHPKGPTYLYDMTQGGELFWTILFNPILIFMTHMNNYGMKERLALSVFKNVTDFVDRWTNLRMQSIPPVEMANKYFELFPKQIEPLWTDPCDDLRHQLIWNHTNKYCIPDKRSTISRLPDVLILGPQKTGTTALLTFLAIHPDIVTSVRSNHSFEEIQFFNKRNYKFGLDWYLNFFPETRKSKDLVYIDKSANYFDSLKAPLRASSFLPQAKLVVILIDPRLRAYSWFQHMRSKSPMVPYPHTFYEVISTKNLTNDHEFDMLTAKCLLPGRYAESIERWLQYYDSSKLLVLDGDELKHKPIMTMSKVQTFLRLSP-YPFHKHITYSSKKKYFCRFFH-NKHYCLGKGKGRDYGKMTGKEWQFLSNYYHLPNLKLYDLLKKLGKIIPVWLQKEIDLVQ 938
            +VL+F  S+ S     + A+  S +  +  +      D    +P   D  G  +Y   I+ +   Y   D +N EL++++C  +++ II   H  +  ++ + QL   PL L    NNL   +    P + +L + K+P V KG LPG+   +F   H T++ +++T+              +  ++     TL+     A  + D GL DG+++ +FG +    WL++L+ +D +   S   L   L RYI +D+DDIFVGK G R+  +DV+A++E Q  L T++ NF FN+G+SG+ Y    +  E EGD  L++S     F WF H  +H++PH F +   L++    NK+FA   G+ ++  YAVAPHHSGVYPVH  LY AW+ V+GIQVTSTE YPHLKPA  RKGF++  IMVLPRQTCGLFT T+    +P GP  L    +GGELF TIL NPI IFMTH++NYG  +RL L  F N+ +FV  WTNL++Q++PPV++A++YFELFP+Q +PLW +PCDD RH+ IW+         +  T   LP  L++GPQKTGTTAL  FL +HP I++++ S  +FEE+QFFN  NY  G+DWY++FFP    +      +KSANYF S +AP RA+S +P+AK++ ILIDP  RAYSW+QH RS          FYEVIST +     +   L  +CL+PG YA  IERWL Y+ +S+LL++DG +L+  P   M +VQ FL ++P Y + + +T+  +K ++C+     K  CLGK KGR Y  M  +   FLSNYY   N++L  LL +LG+ +P WL++E+  V+
Sbjct:   79 TVLLFVESQYSQLGQDIIAILESSRFQYHMVIAPGKGD----IPPLTDN-GKGKYTLVIYENILKYVSMDSWNRELLEKYCVEYSVSIIGF-HKANENSLPSTQLKGFPLNLF---NNLALKDCFVNPQSPLLHITKAPKVEKGPLPGEDWTIFQYNHSTYQPVLLTE-----------LQTEKSLSSLSSKTLF-----ATVIQDLGLHDGIQRVLFGNNL-NFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTE-EEDEGDDLLLRSV--DEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINMGYAVAPHHSGVYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIRGGELFLTILLNPISIFMTHLSNYG-NDRLGLYTFVNLVNFVQSWTNLKLQTLPPVQLAHQYFELFPEQKDPLWQNPCDDKRHKDIWS---------REKTCDHLPKFLVIGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTPSNTTSDFLFEKSANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVISTGHWAPS-DLKTLQRRCLVPGWYAVHIERWLTYFATSQLLIIDGQQLRSDPATVMDEVQKFLGVTPRYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLSNYYRDHNVELSKLLHRLGQPLPSWLRQELQKVR 872          
The following BLAST results are available for this feature:
BLAST of TCONS_00000215-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NDST40.000e+041.61Bifunctional heparan sulfate N-deacetylase/N-sulfo... [more]
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