TCONS_00000162-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00000162-protein
Unique Name	TCONS_00000162-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1365

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00000162-protein ID=TCONS_00000162-protein|Name=TCONS_00000162-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1365bp
MFNHAQTISKIAFLHAKYENIVQSFLPRHSGLVVESNHPFDPKIFINSNW
IVSIDYFLLDMKYRMITLFKFMVLLYAGSQVLAQTNIRKDGYCVMYGQMA
PGTEIVNPYNGPAKNFSEESYKILAETCPHLAHGINETVGCCGIGQLKSL
EKNLKTAATLFSRCPSCSKNFYNMWCDFTCSPNQSEFMDYTYGMATYYVS
DKYANDLYGSCKDVTFPGSNGKVMDLMCGTTAKLCTTEKFLKFVGTPGNG
APFNIMFNIGLNVSGVENHDAHMVGCNETYAISSDKNSTVCSCQDCQPSC
PVPPSPPQPKPIKYIMGIRETYFITGVVLLVWVFVFLAFSVFEIFRSRDS
SLEARADAVHSGSVSSNGSGYHNSTTALYGGYQQNPGKCVGLGIKAEEFL
QKIFQKWGTLCASHPWKVILGSLFFILVCSLGLLKFTVITNPVELWSSPT
TQARMEKSYYDEKFTPFYRTEQVIITSTVKNNTEEFYPYQVSSPTNFSGI
MTKEMLFRVLDLQLDLMNLTAEYNGETVALNDICYQPLYPDNKDCAVMSV
LQYWQLDAKKLNMCITNMDSDCSAGFGSRAADWHDQFSGCTKNPTAMELE
PHMKLPCMGKFGGPVTPKLALGGFEGDDYSTATTLIITFVVNNHRDESKN
KKAEAWEKVFIDYLKKWEQDPELSANLTIAYTSERSIQDEITRASESDVL
TIAISYCLMFLYIAVGLGQFRSLSRMLIDAKVTVGIIGVLIVLLSVAASL
GACSYFGTPATLIIIEVIPFLVLAVGVDNIFILVQALQRDIRLPAENTSE
QVGRVVGVVGPSMLLSSLSESVAFGFGALSTMPAVHTFAVFACFAVFFNF
ILQMTMLVAVVTLDKKRQDNSRYDILCCASGDKNAPNSEECCEGGVLHFI
VKKIYAPTLMLYPVRVTVILVFSIYLGISACFITNLSLGISQTIALPRDS
FLMNYFGNLSTYLKTGAPVYFVVKDGFDYSKVENQNLLCGSSGCNSNSLL
GEVFFSSLNPNYTSVALPASSWLDDYFSWLDPDVKCCRLRNGSTPLNMNF
CPATDPLEWRNCTSCLPKNESAQRPRPAEFRKFLQQYLKDNPSKDCSKGG
HAAYGGAVKLNAPVDGEYSVDASYFMTYHTVSTTSDEFTHSMKYARELAS
NMTERINHDVFAYSVFYVFYEQYLTIVSDTWKDLLICASGVFAVTFLLMG
FNFGLAFCIIVTVAMIVVDLMGLMYLWNISLNAVSLVNLMMAIGISVEFC
AHIGRAFSTSPYSSRVKRAEDALGTVGSSVLSGITITKFVGVFVLWFSKS
ELFEIYYFRMYMGIIIMGFLHGLVFLPVFLSYVGPASRATEEDVKRASMA
TNAHPAAREKKLISA

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_000094	XLOC_000094	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00000162	TCONS_00000162	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR004765	NP_C_type
IPR032190	NPC1_N
IPR003392	Ptc/Disp
IPR000731	SSD

Vocabulary: **Molecular Function**
Term	Definition
GO:0005319	lipid transporter activity

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005319	lipid transporter activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

ZOOM

x 1

POSITION

0


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	1.20.1640.10		coord: 644..874 e-value: 6.5E-42 score: 142.7 coord: 1137..1347 e-value: 1.5E-31 score: 108.8
None	No IPR available	SUPERFAMILY	82866	Multidrug efflux transporter AcrB transmembrane domain	coord: 663..863
None	No IPR available	SUPERFAMILY	82866	Multidrug efflux transporter AcrB transmembrane domain	coord: 1144..1334
IPR004765	Niemann-Pick C type protein	TIGRFAM	TIGR00917	TIGR00917	coord: 93..1334 e-value: 0.0 score: 1256.7
IPR032190	Niemann-Pick C1, N-terminal	PFAM	PF16414	NPC1_N	coord: 91..316 e-value: 2.0E-59 score: 201.0
IPR003392	Protein patched/dispatched	PFAM	PF02460	Patched	coord: 1115..1333 e-value: 6.8E-32 score: 110.4 coord: 627..985 e-value: 5.8E-49 score: 166.8
IPR000731	Sterol-sensing domain	PROSITE	PS50156	SSD	coord: 698..863 score: 40.228

Blast

[Close]

BLAST of TCONS_00000162-protein vs. Swiss-Prot (Human)
Match: NPC1 (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 1009.98 bits (2610), Expect = 0.000e+0
Identity = 567/1318 (43.02%), Postives = 799/1318 (60.62%), Query Frame = 0

Query:   79 SQVLAQTNIRKDGYCVMYGQ--MAPGTEIVN-PYNGPAKNFSEESYKILAETCPHLAHGINETVGCCGIGQLKSLEKNLKTAATLFSRCPSCSKNFYNMWCDFTCSPNQSEFMDYT----------------YGMATYYVSDKYANDLYGSCKDVTFPGSNGKVMDLMCGTTAKLCTTEKFLKFVGTPGNG-APFNI--MFNIGLNVSGVENHDAHMVGCNETYAISSDKNSTVCSCQDCQPSCPVPPSPPQPKPIKYIMGIRETYFITGVVLLVWVFVFL-AFSVFEIFRSR---------DSSLEARADAVHSGSVSSNGSGYHNSTTALYGGYQQNPGKCVGLGIKAEEFLQKIFQKWGTLCASHPWKVILGSLFFILVCSLGLLKFTVITNPVELWSSPTTQARMEKSYYDEKFTPFYRTEQVIITSTVKNNTEEFYPYQVSSPTNFSGIMTKEMLFRVLDLQLDLMNLTAEYNGETVALNDICYQPLYPDNKDCAVMSVLQYWQ-----LDAKKLNMCITNMDSDCSAGFGSRAADWHDQFSGCTKNPTAMELEPHMKLPCMGKFGGPVTPKLALGGFEGDDYSTATTLIITFVVNNH-RDESKNKKAEAWEKVFIDYLKKWEQDPELSANLTIAYTSERSIQDEITRASESDVLTIAISYCLMFLYIAVGLGQFRSLSRMLIDAKVTVGIIGVLIVLLSVAASLGACSYFGTPATLIIIEVIPFLVLAVGVDNIFILVQALQRDIRLPAENTSEQVGRVVGVVGPSMLLSSLSESVAFGFGALSTMPAVHTFAVFACFAVFFNFILQMTMLVAVVTLDKKRQDNSRYDILCCASGDKNAPNSEECCEGGVLHFIVKKIYAPTLMLYPVRVTVILVFSIYLGISACFITNLSLGISQTIALPRDSFLMNYFGNLSTYLKTGAPVYFVVKDGFDYSKVENQNLLCGSSGCNSNSLLGEVFFSSLNPNYTSVALPASSWLDDYFSWLDPDVKCCRLRNGSTPLNMNFCPAT--DPLEWRNCTSCLPKN-ESAQRPRPAEFRKFLQQYLKDNPSKDCSKGGHAAYGGAVKLNAPVDGEYSVDASYFMTYHTVSTTSDEFTHSMKYARELASNMTERIN-----HDVFAYSVFYVFYEQYLTIVSDTWKDLLICASGVFAVTFLLMGFNFGLAFCIIVTVAMIVVDLMGLMYLWNISLNAVSLVNLMMAIGISVEFCAHIGRAFSTSPYSSRVKRAEDALGTVGSSVLSGITITKFVGVFVLWFSKSELFEIYYFRMYMGIIIMGFLHGLVFLPVFLSYVGPA-----SRATEEDVK 1345
            +QV +Q+       CV YG+  +A G +  N  Y+GP K   ++ Y ++ E CP    G N ++ CC + QL++L+ NL+      SRCPSC  N  N++C+ TCSP QS+F++ T                     YYV   +AN +Y +C+DV  P SN K + L+CG  A  C    +++++    NG APF I  +F+    V G+E  +    GC+E    S D+ +  CSCQDC   C   P PP P     I+G+   Y I  +  + ++ VF  AF     +R R         DS++    +A   G  S                       C  +    E  L+++F +WG+ C  +P  VI  SL FI  CS GL+   V TNPV+LWS+P++QAR+EK Y+D+ F PF+RTEQ+II + + +    + PY   +   F   +  ++L +VLDLQ+ + N+TA Y+ ETV L DIC  PL P N +C ++SVL Y+Q     LD KK +                  AD+H  F  C + P ++     +  PC+G FGGPV P L LGG++  +Y+ AT L+ITF VNN+  D  K ++A+AWEK FI+++K ++     + NLTI++T+ERSI+DE+ R S+SDV T+ ISY +MFLYI++ LG  +S  R+L+D+KV++GI G+LIVL SVA SLG  SY G P TLI+IEVIPFLVLAVGVDNIFILVQA QRD RL  E   +Q+GRV+G V PSM LSS SE+VAF  GALS MPAVHTF++FA  AVF +F+LQ+T  V+++ LD KRQ+ +R DI CC  G ++   S +  E  +  F  K  Y+P L+   +R  VI +F   L  S   +  + +G+ Q++++P DS++++YF ++S YL  G PVYFV+++G DY+  + QN++CG  GCN++SL+ ++F ++   NYT +    SSW+DDYF W+ P   CCR+ N    +   FC A+  DP     C  C P   E  QRP+  +F +FL  +L DNP+  C KGGHAAY  AV  N  +     V A+YFMTYHTV  TS +F  ++K AR +ASN+TE +      + VF YSVFYVFYEQYLTI+ DT  +L +    +F VT +L+G     A  +  T+AM++V++ G+M+LW ISLNAVSLVNL+M+ GISVEFC+HI RAF+ S   SRV+RAE+AL  +GSSV SGIT+TKF G+ VL F+KS++F+I+YFRMY+ ++++G  HGL+FLPV LSY+GP+     S ATEE  K
Sbjct:   18 AQVFSQS-------CVWYGECGIAYGDKRYNCEYSGPPKPLPKDGYDLVQELCPGFFFG-NVSL-CCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFS-DFPVHGMEPMNNATKGCDE----SVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAFSVNASDKGEASC----------------------CDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDK-HIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFV-------------YADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYK-----NPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDG-TSVQASESCLFRFF-KNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDN----ITDQFCNASVVDP----ACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAV--NILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKSCATEERYK 1268

The following BLAST results are available for this feature:

BLAST of TCONS_00000162-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00000162-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

ZOOM

x 1

POSITION

0


Match Name	E-value	Identity	Description
NPC1	0.000e+0	43.02	Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE...	[more]

You are here

TCONS_00000162-protein (polypeptide) - C. hemisphaerica

ZOOM

x 1

POSITION

0

ZOOM

x 1

POSITION

0