Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
The following browser provides a quick view for new visitors. Use the searching mechanism to find specific features.
NameUnique NameType
BlTCONS00000151BlTCONS00000151transcript
BlTCONS00000152BlTCONS00000152mRNA
BlTCONS00000153BlTCONS00000153mRNA
BlTCONS00000154BlTCONS00000154transcript
BlTCONS00000155BlTCONS00000155mRNA
BlTCONS00000156BlTCONS00000156mRNA
BlTCONS00000157BlTCONS00000157mRNA
BlTCONS00000158BlTCONS00000158mRNA
BlTCONS00000159BlTCONS00000159mRNA
BlTCONS00000160BlTCONS00000160mRNA
BlTCONS00000161BlTCONS00000161mRNA
BlTCONS00000162BlTCONS00000162mRNA
BlTCONS00000163BlTCONS00000163mRNA
BlTCONS00000164BlTCONS00000164mRNA
BlTCONS00000165BlTCONS00000165transcript
BlTCONS00000166BlTCONS00000166mRNA
BlTCONS00000167BlTCONS00000167mRNA
BlTCONS00000168BlTCONS00000168mRNA
BlTCONS00000169BlTCONS00000169mRNA
BlTCONS00000170BlTCONS00000170mRNA
BlTCONS00000171BlTCONS00000171mRNA
BlTCONS00000172BlTCONS00000172mRNA
BlTCONS00000173BlTCONS00000173mRNA
BlTCONS00000174BlTCONS00000174mRNA
BlTCONS00000175BlTCONS00000175mRNA

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