Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
The following browser provides a quick view for new visitors. Use the searching mechanism to find specific features.
NameUnique NameType
transcript:BL00161_evm5transcript:BL00161_evm5mRNA
transcript:BL00162_evm0transcript:BL00162_evm0mRNA
transcript:BL00163_evm0transcript:BL00163_evm0mRNA
transcript:BL00164_evm0transcript:BL00164_evm0mRNA
transcript:BL00165_evm0transcript:BL00165_evm0mRNA
transcript:BL00166_evm0transcript:BL00166_evm0mRNA
transcript:BL00167_evm0transcript:BL00167_evm0mRNA
transcript:BL00168_evm0transcript:BL00168_evm0mRNA
transcript:BL00169_evm0transcript:BL00169_evm0mRNA
transcript:BL00170_evm0transcript:BL00170_evm0mRNA
transcript:BL00171_evm0transcript:BL00171_evm0mRNA
transcript:BL00172_evm0transcript:BL00172_evm0mRNA
transcript:BL00173_evm0transcript:BL00173_evm0mRNA
transcript:BL00174_cuf3transcript:BL00174_cuf3mRNA
transcript:BL00175_evm0transcript:BL00175_evm0mRNA
transcript:BL00176_cuf25transcript:BL00176_cuf25mRNA
transcript:BL00177_evm0transcript:BL00177_evm0mRNA
transcript:BL00179_cuf2transcript:BL00179_cuf2mRNA
transcript:BL00180_evm0transcript:BL00180_evm0mRNA
transcript:BL00181_evm0transcript:BL00181_evm0mRNA
transcript:BL00182_cuf7transcript:BL00182_cuf7mRNA
transcript:BL00184_evm0transcript:BL00184_evm0mRNA
transcript:BL00185_evm9transcript:BL00185_evm9mRNA
transcript:BL00186_evm0transcript:BL00186_evm0mRNA
transcript:BL00188_cuf0transcript:BL00188_cuf0mRNA

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