Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
The following browser provides a quick view for new visitors. Use the searching mechanism to find specific features.
NameUnique NameType
transcript:BL00646_cuf1transcript:BL00646_cuf1mRNA
transcript:BL00648_cuf0transcript:BL00648_cuf0mRNA
transcript:BL00649_evm0transcript:BL00649_evm0mRNA
transcript:BL00650_cuf2transcript:BL00650_cuf2mRNA
transcript:BL00651_cuf1transcript:BL00651_cuf1mRNA
transcript:BL00652_evm0transcript:BL00652_evm0mRNA
transcript:BL00653_evm0transcript:BL00653_evm0mRNA
transcript:BL00654_evm0transcript:BL00654_evm0mRNA
transcript:BL00655_evm0transcript:BL00655_evm0mRNA
transcript:BL00657_cuf1transcript:BL00657_cuf1mRNA
transcript:BL00658_evm0transcript:BL00658_evm0mRNA
transcript:BL00659_cuf0transcript:BL00659_cuf0mRNA
transcript:BL00660_cuf11transcript:BL00660_cuf11mRNA
transcript:BL00661_evm0transcript:BL00661_evm0mRNA
transcript:BL00662_cuf4transcript:BL00662_cuf4mRNA
transcript:BL00663_evm0transcript:BL00663_evm0mRNA
transcript:BL00664_evm0transcript:BL00664_evm0mRNA
transcript:BL00665_cuf4transcript:BL00665_cuf4mRNA
transcript:BL00666_evm0transcript:BL00666_evm0mRNA
transcript:BL00667_cuf1transcript:BL00667_cuf1mRNA
transcript:BL00668_evm1transcript:BL00668_evm1mRNA
transcript:BL00669_evm0transcript:BL00669_evm0mRNA
transcript:BL00670_cuf4transcript:BL00670_cuf4mRNA
transcript:BL00671_cuf3transcript:BL00671_cuf3mRNA
transcript:BL00672_evm0transcript:BL00672_evm0mRNA

Pages