Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
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NameUnique NameType
BlTCONS00000376BlTCONS00000376mRNA
BlTCONS00000377BlTCONS00000377mRNA
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BlTCONS00000379BlTCONS00000379mRNA
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BlTCONS00000382BlTCONS00000382mRNA
BlTCONS00000383BlTCONS00000383mRNA
BlTCONS00000384BlTCONS00000384mRNA
BlTCONS00000385BlTCONS00000385mRNA
BlTCONS00000386BlTCONS00000386mRNA
BlTCONS00000387BlTCONS00000387mRNA
BlTCONS00000388BlTCONS00000388mRNA
BlTCONS00000389BlTCONS00000389mRNA
BlTCONS00000390BlTCONS00000390mRNA
BlTCONS00000391BlTCONS00000391mRNA
BlTCONS00000392BlTCONS00000392mRNA
BlTCONS00000393BlTCONS00000393mRNA
BlTCONS00000394BlTCONS00000394mRNA
BlTCONS00000395BlTCONS00000395mRNA
BlTCONS00000396BlTCONS00000396transcript
BlTCONS00000397BlTCONS00000397mRNA
BlTCONS00000398BlTCONS00000398mRNA
BlTCONS00000399BlTCONS00000399mRNA
BlTCONS00000400BlTCONS00000400mRNA

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