Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
The following browser provides a quick view for new visitors. Use the searching mechanism to find specific features.
NameUnique NameType
transcript:BL00301_evm3transcript:BL00301_evm3mRNA
transcript:BL00302_evm2transcript:BL00302_evm2mRNA
transcript:BL00303_evm4transcript:BL00303_evm4mRNA
transcript:BL00304_cuf3transcript:BL00304_cuf3mRNA
transcript:BL00306_evm0transcript:BL00306_evm0mRNA
transcript:BL00307_evm0transcript:BL00307_evm0mRNA
transcript:BL00308_evm1transcript:BL00308_evm1mRNA
transcript:BL00309_evm2transcript:BL00309_evm2mRNA
transcript:BL00310_cuf2transcript:BL00310_cuf2mRNA
transcript:BL00311_cuf4transcript:BL00311_cuf4mRNA
transcript:BL00312_evm0transcript:BL00312_evm0mRNA
transcript:BL00313_evm0transcript:BL00313_evm0mRNA
transcript:BL00314_evm0transcript:BL00314_evm0mRNA
transcript:BL00316_cuf0transcript:BL00316_cuf0mRNA
transcript:BL00317_evm0transcript:BL00317_evm0mRNA
transcript:BL00318_evm2transcript:BL00318_evm2mRNA
transcript:BL00319_cuf18transcript:BL00319_cuf18mRNA
transcript:BL00320_evm0transcript:BL00320_evm0mRNA
transcript:BL00321_evm0transcript:BL00321_evm0mRNA
transcript:BL00322_cuf1transcript:BL00322_cuf1mRNA
transcript:BL00323_cuf1transcript:BL00323_cuf1mRNA
transcript:BL00324_cuf1transcript:BL00324_cuf1mRNA
transcript:BL00325_evm0transcript:BL00325_evm0mRNA
transcript:BL00326_cuf1transcript:BL00326_cuf1mRNA
transcript:BL00327_evm0transcript:BL00327_evm0mRNA

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