TCONS_00069465-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00069465-protein
Unique NameTCONS_00069465-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length932

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00069465-protein ID=TCONS_00069465-protein|Name=TCONS_00069465-protein|organism=Clytia hemisphaerica|type=polypeptide|length=932bp
VKTDKKMDINYIKLHGVDSTRYNLTSSVVEKGGGRRRSPSPRVVHKRAQS
PIIDPQLEADMNRVKKQVPKVQKARLYLLQQPGPNSFLIGGDSPDHKYKV
IVGPQTCTCGKDPFCIHILFVMLRVFKVKENDPLLWNRELKNFEVESLFR
KYHKRLALLTKQKVRPSTLAVKDKISTSISPLPDPLHAAGHTTHGHHTVK
EEEEVCPICLSDLVEGESMTLCKEGCQNRLHHHCMAVWAEECRRRKEALN
CPLCRTIWQSRRSSSPFKMTRSGTPTEQVDIQQDDHGLPRGEVIPEQYQE
MAQSWVQVFGNDPVACLFSKDWKHRECGLRFISRKAVKVLSEKRTTVSYR
ETKWELLSVCTAVLAYIVSDPVYNVYVAALRAFRAIVTNVRYQTQEELNT
LHLTIKPVIEKILIKCSDSNRRVTILSMKILMEFVSGETASIQNPSNSTI
NNTQQHMDLIASCLNQEEDQTQWQWWLGRLTFVRRLFDEHHSQLLLASEN
RINMASSLPVSPNSDVDLREFLNSLAENVHSDTKFTSKTCERILLLARFS
ARALSCPHQKVHRHALFLMIKCIAISSQDSVLYPSIKQIVYGLTSNHQST
LHRHLSNESQREQADILNILGEHGEERNEQNATSVVEEEEQHSLEEVSLQ
HQTPTSARLQDVSTSPIASPSTPEVHPPHLSPPTSSYDPHLKCVRAVEDE
EAAAIAIALDRSQRRPENVIPEQLIPTDDLTIVHIQPDGDKKSKDGEVCK
PRNVYLEEIHWKKGGLVGTGAFSSCYEAMDFKSGRIMAVKQISFVRNTEE
EQEKVHQIVLEEIALLHRIKHPNIVSCLGATQHEAHYNLFMELMPGGSIS
SLLGKFGAFRESVTKSYTQQILQAVTYLHQHHTLHRDLKGANLLVDSTGQ
IVKLSDFGTAARLMAHGTGTKEFCXISARPLV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_043292XLOC_043292Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00069465TCONS_00069465Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR001841Znf_RING
IPR007527Znf_SWIM
IPR013083Znf_RING/FYVE/PHD
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom
IPR016024ARM-type_fold
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0008270zinc ion binding
GO:0005488binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005488 binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 761..932
e-value: 1.2E-16
score: 71.3
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 762..923
e-value: 1.9E-39
score: 135.6
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 761..932
score: 28.838
NoneNo IPR availableGENE3D1.10.510.10coord: 833..926
e-value: 8.0E-28
score: 97.0
NoneNo IPR availableGENE3D3.30.200.20coord: 594..832
e-value: 9.8E-19
score: 66.9
NoneNo IPR availableSUPERFAMILY57850RING/U-boxcoord: 200..263
IPR001841Zinc finger, RING-typePFAMPF13639zf-RING_2coord: 206..255
e-value: 1.1E-6
score: 28.8
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 206..255
score: 10.085
IPR007527Zinc finger, SWIM-typePFAMPF04434SWIMcoord: 98..124
e-value: 6.4E-4
score: 19.2
IPR007527Zinc finger, SWIM-typePROSITEPS50966ZF_SWIMcoord: 98..126
score: 8.852
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3D3.30.40.10coord: 188..286
e-value: 3.3E-10
score: 38.9
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 767..790
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 761..920
IPR016024Armadillo-type foldSUPERFAMILY48371ARM repeatcoord: 315..603

Blast
[Close]
BLAST of TCONS_00069465-protein vs. Swiss-Prot (Human)
Match: M3K1 (Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4)

HSP 1 Score: 326.635 bits (836), Expect = 2.394e-94
Identity = 193/540 (35.74%), Postives = 281/540 (52.04%), Query Frame = 0 
Query:   30 EKGGGRRRSPSP------RVVH-KRAQSPI-IDPQLEADMNRVKKQVPKVQKARLYLLQQPGPNSFLIGGDSPDHKYKVIVGPQTCTCGKDPFCIHILFVMLRVFKVKENDPLLWNRELKNFEVESLFRKYHKRLALLTKQKVRPSTLAVKDKISTSISPLPDPLHAAGHTTHGHHTVKEEEEVCPICLSDLVEGESMTLCKEGCQNRLHHHCMAVWAEECRRRKEALNCPLCRTIWQS-----------------------------------RRSSSPFKMTRSGTPTEQVDIQQDDHGLPRGEVIPEQYQEMAQSWVQVFGNDPVACLFSKDWKHRECGLRFISRKAVKVL-------------------------SEKRTTVSYRETKWELLSVCTAVLAYIVSDPVYNVYVAALRAFRAIVTNVRYQTQEELNTLHLTIKPVIEKILIKCSDSNRRVTILSMKILMEFVSGETA------SIQNPSNSTINNTQQHMDLIASC-LNQEEDQTQWQWWLGRLTFVRRLFDEHHSQL 494
            E  G RR+  SP      R+   +RA SP    P    + NR   +V KV +ARLYLLQQ GPNSFLIGGDSPD+KY+V +GPQ C+C +  FCIH+LFVMLRVF+++ +DP+LW + LKNFEVESLF+KYH R +   K    PS   ++  +S   +       +   ++  +    EEE++CPICL  +++ ES+T+C++GC+N+LHHHCM++WAEECRR +E L CPLCR+ W+S                                   R   S F +T  GT       QQ          IP  Y+++A+ W+QVFG + V CLFS++W  RE  LR +S      L                            +T++S      +++  C +VL+ + +DPVY VYVAAL+  RA++      +  E   L   ++PV++ IL+KC+D+N R + LS+  L+E   G+         I    +  I      +D + +C L  + +   WQ  LGRL  + RL  E  ++ 
Sbjct:  265 ESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETNR---RVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCARGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKA---PSRNTIQKFVSRMSNSHTLSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVDSPSSLRAAQQQTVQQQPLAGSRRNQESNFNLTHYGT-------QQ----------IPPAYKDLAEPWIQVFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLANGESTGNSGGSSGSSPSGGATSGSSQTSIS-----GDVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLQPVVDTILVKCADANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGIGG----VDYVLNCILGNQTESNNWQELLGRLCLIDRLLLEFPAEF 772

HSP 2 Score: 210.305 bits (534), Expect = 9.701e-56
Identity = 92/174 (52.87%), Postives = 132/174 (75.86%), Query Frame = 0 
Query:  750 KPRNVYLEEIHWKKGGLVGTGAFSSCYEAMDFKSGRIMAVKQISFVRNTEEEQEKVHQIVLEEIALLHRIKHPNIVSCLGATQHEAHYNLFMELMPGGSISSLLGKFGAFRESVTKSYTQQILQAVTYLHQHHTLHRDLKGANLLVDSTGQIVKLSDFGTAARLMAHGTGTKEF 923
            K +  Y E+  W KG  +G GAFSSCY+A D  +G +MAVKQ+++VRNT  EQE+V + + EEI ++  + HPNI+  LGAT  +++YNLF+E M GGS++ LL K+GAF+ESV  +YT+Q+L+ ++YLH++  +HRD+KGANLL+DSTGQ ++++DFG AARL + GTG  EF
Sbjct: 1232 KAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEF 1405
The following BLAST results are available for this feature:
BLAST of TCONS_00069465-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
M3K12.394e-9435.74Mitogen-activated protein kinase kinase kinase 1 O... [more]
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