TCONS_00051806-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00051806-protein
Unique Name	TCONS_00051806-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	902

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00051806-protein ID=TCONS_00051806-protein|Name=TCONS_00051806-protein|organism=Clytia hemisphaerica|type=polypeptide|length=902bp
MMSKLTMFSLAFCTIFCLSVESAKLTKDHSKLDFIEITSFEKIGDRRKRD
TKNQDTTEEYALKTPSKDYHLVLKPSSHIIGPNLFEDEKSWEQENCHYQG
LEKNFGGQVLLSTCGGTLNGLLVDGKQNKTYMVEYEESLANHIVYEVDKL
PQNKRITMATDIQRNEITKVEGVNIKANHRARRDVSVDASDVSVDASDVE
KYASLVMVVDNSAFVHLGSDKTKVIHFVLAIVNHMDFLFRQANIHVILTH
LEIWDVSDKFTVTATTSDNLNHFTQYNKDIMINQNGWRHDNAHFLTHVDQ
QGGLVGLGAVGSICGQGGLSQAMSQIWSDNPLITAGTVAHEFGHNVGLYH
FTSECICDNPPCLMSSYANWSPVRGLTDCTKKVIEDRCSLGKCSCLTDQP
AASYMGATCGNGIVEKGEDCDCGQPEYCTNKCCDASTCKFQTHAQCAEGE
CCTDDCQLKAKDVLCRDAQGECDLPETCDGKQATCPLDVYLQDYQDCNSK
TSYCYKGKCTKTLNEQCETLWGNEADHSRTCIRNYKGDKFGHCGTDKNGK
FIPCETKNEFCGKVQCHGDIASHFIVFGRSRSTAVYGSQCRSGLTYVGEN
INPTMAFDGTKCDAGKVCQNQQCIATDIAKSTSKCDDRCHFGRCTNVGAC
YCPPKFKCPDCSRMDPNNINGQVCSEQPSQTHRHHDGKLNWEEYLDLLTS
NLFLTRWKARVTFKNRVSTGDTLDKYVPTKKIDSVDHAIDNLFKDLKDMN
LAPTTTTTTTTTTTTTTPTTTPTTTPTTTPTTTPTTTTTVAPLCLDAVGM
INIGCRSKSGGTMIANYRNAMDWNNPSDSIEKMICDCAKTAKDDGYVGFG
LVYWGECWGYSTKDEAVNQSGSTNCSNDQYNSCAEEDRICIGKADASYAF
LL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_032802	XLOC_032802	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00051806	TCONS_00051806	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001762	Disintegrin_dom
IPR006586	ADAM_Cys-rich
IPR024079	MetalloPept_cat_dom
IPR002870	Peptidase_M12B_N
IPR001590	Peptidase_M12B
IPR018358	Disintegrin_CS
IPR034027	Reprolysin_adamalysin

Vocabulary: **Molecular Function**
Term	Definition
GO:0008237	metallopeptidase activity
GO:0004222	metalloendopeptidase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006508	proteolysis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
molecular_function	GO:0004222	metalloendopeptidase activity
molecular_function	GO:0008237	metallopeptidase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001762	Disintegrin domain	SMART	SM00050	DISIN_2	coord: 415..491 e-value: 1.8E-34 score: 130.5
IPR001762	Disintegrin domain	GENE3D	4.10.70.10		coord: 419..489 e-value: 2.0E-21 score: 76.0
IPR001762	Disintegrin domain	PFAM	PF00200	Disintegrin	coord: 415..488 e-value: 9.9E-19 score: 67.8
IPR001762	Disintegrin domain	PROSITE	PS50214	DISINTEGRIN_2	coord: 406..493 score: 18.357
IPR001762	Disintegrin domain	SUPERFAMILY	57552	Blood coagulation inhibitor (disintegrin)	coord: 415..491
IPR006586	ADAM, cysteine-rich	SMART	SM00608	acr	coord: 492..626 e-value: 4.4E-28 score: 109.3
IPR006586	ADAM, cysteine-rich	PFAM	PF08516	ADAM_CR	coord: 493..569 e-value: 3.9E-17 score: 62.6
IPR024079	Metallopeptidase, catalytic domain	GENE3D	3.40.390.10		coord: 197..418 e-value: 1.3E-40 score: 138.9
IPR002870	Peptidase M12B, propeptide	PFAM	PF01562	Pep_M12B_propep	coord: 43..136 e-value: 1.9E-9 score: 37.8
IPR001590	Peptidase M12B, ADAM/reprolysin	PFAM	PF01421	Reprolysin	coord: 201..400 e-value: 3.0E-38 score: 131.6
IPR001590	Peptidase M12B, ADAM/reprolysin	PROSITE	PS50215	ADAM_MEPRO	coord: 201..400 score: 32.873
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 753..785
None	No IPR available	SUPERFAMILY	55486	Metalloproteases ("zincins"), catalytic domain	coord: 201..400
IPR018358	Disintegrin, conserved site	PROSITE	PS00427	DISINTEGRIN_1	coord: 446..466
IPR034027	Reprolysin domain, adamalysin-type	CDD	cd04269	ZnMc_adamalysin_II_like	coord: 201..398 e-value: 2.78475E-40 score: 146.992

Blast

[Close]

BLAST of TCONS_00051806-protein vs. Swiss-Prot (Human)
Match: ADA12 (Disintegrin and metalloproteinase domain-containing protein 12 OS=Homo sapiens GN=ADAM12 PE=1 SV=3)

HSP 1 Score: 273.478 bits (698), Expect = 2.075e-78
Identity = 198/590 (33.56%), Postives = 290/590 (49.15%), Query Frame = 0

Query:   95 NCHYQGLEKNFG-GQVLLSTCGGTLNGLLVDGKQNKTYMVEYEESLANHIVYEVDKLPQNKRITMATDIQRNEITKVEGVNIKANHRARRDVSVDASDVSVDASDVEKYASLVMVVDNSAFVHLGSDKTKVIHFVLAIVNHMDFLFRQANIHVILTHLEIWDVSDKFTVTATTSDNLNHFTQYNKDIMINQNGWRHDNAHFLTHVDQQGGLVGLGAVGSICGQGGLSQAMSQIWSDNPLITAGTVAHEFGHNVGLYHFTSE--CIC----DNPPCLMSSYANWSPVRGLTDCTKKVIEDRCSLGKCSCLTDQPAA--SYMGATCGNGIVEKGEDCDCGQPEYCTNKCCDASTCKFQTHAQCAEGECCTDDCQLKAKDVLCRDAQGECDLPETCDGKQATCPLDVYLQDYQDCNSKTSYCYKGKCTKTLNEQCETLWGNEADHSR-TCIR--NYKGDKFGHCGTDKNGKFIPCETKNEFCGKVQCHGDIASHFI-VFGRSRSTAVYGSQ-----CRSGLTYVGENI-NPTMAFDGTKCDAGKVCQNQQCIATDIAKSTSKCDDRCH-FGRCTNVGACYCPPKFKCPDCSRM 664
            +C+Y G  + +    V LSTC G L GL+V   +N++Y++E  +S  N   Y++    + K +  +     N        N+ A +         A     +     KY  LV+V DN  F   G D  KV   ++ I NH+D  +R  NI ++L  +E+W+  DK +V+     +L+ F  + K  ++ +    HDNA  ++ V  QG  +G+  + S+C     S  +    SDNPL  A T+AHE GHN G+ H T +  C C    +   C+M++   +      + C++K +E     G   CL + P    S+ G  CGN  VE+GE+CDCG+PE C N+CC+A+TC  +  A CA G CC +DCQLK     CRD+   CDLPE C G    CP +VYL D   C     YCY G C +T  +QC TLWG  A  +   C    N  GD +G+CG      F  CE ++  CGK+QC G  +   I     S  T +   Q     CR    Y+G+++ +P +   GTKC  GK+C N+QC    +     +C  +CH  G C N   C+C   +  P C + 
Sbjct:  118 HCYYHGHVRGYSDSAVSLSTCSG-LRGLIVF--ENESYVLEPMKSATNR--YKLFPAKKLKSVRGSCGSHHNT------PNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKS--HDNAQLVSGVYFQGTTIGMAPIMSMC-TADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCC-EDCQLKPAGTACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGIC-QTHEQQCVTLWGPGAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVF-GVHECAMQCHGRGVCNNRKNCHCEAHWAPPFCDKF 690

The following BLAST results are available for this feature:

BLAST of TCONS_00051806-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00051806-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ADA12	2.075e-78	33.56	Disintegrin and metalloproteinase domain-containin...	[more]

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TCONS_00051806-protein (polypeptide) - C. hemisphaerica