TCONS_00009740-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00009740-protein
Unique NameTCONS_00009740-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length583

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00009740-protein ID=TCONS_00009740-protein|Name=TCONS_00009740-protein|organism=Clytia hemisphaerica|type=polypeptide|length=583bp
MKILLALFIFVNLISLSLQIPIKKDHNLHTFKSIFQNLGAHSSTGCTICK
GLVEILHGVGSTGLGEGELINIATKICLKAKIEDNNVCNSVTREFADELW
YVLMDAALQPEKVCGWIFGDSCLHYVDYFPSWNITIPPRTRPATNSWKTQ
KSNVNPKKILHFSDTHIDFDYLQGSNAVCNEPLCCRPVNGKAGPNDTAAP
KWGFPGNCDANPLLVNNLFNHIALAHEDAEYIYWTGDVPAHNVWNQSRED
QIFTIKQATKLLVQYFPHKKVFPALGNHEGAPVNSFPPPYITGQQSLSWL
LDTLAEDWTTWLPKDTEETIRRGGFYTVLVEEGFRVISLNMNYGNEGNWW
LWINSKDPAGQLQWLADTLYKAEQNNEKVHILGHIPPSGTLLWFRFNYYR
IVDRFHDTIAAQFFGHTHHDEFSLFYHSDDTEVPNNIAYIGPSVTTYNNM
NPGYRTYDVDGSTTNATWNVINHDTFYAEIQKTDDTHPPEWLHEYNAKEA
YGMKDLSPGQWHSLIQRMYNDPELFQIMFKAYRKQYKYDTCDTLKCRRSF
LCGMMDGPFKSCDLSAEEYAIFERIRAQASTNC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_005447XLOC_005447Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00009740TCONS_00009740Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR008139SaposinB_dom
IPR011160Sphingomy_PDE
IPR004843Calcineurin-like_PHP_ApaH
IPR029052Metallo-depent_PP-like
IPR011001Saposin-like
Vocabulary: Molecular Function
TermDefinition
GO:0004767sphingomyelin phosphodiesterase activity
GO:0016787hydrolase activity
Vocabulary: Biological Process
TermDefinition
GO:0006685sphingomyelin catabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006685 sphingomyelin catabolic process
molecular_function GO:0016787 hydrolase activity
molecular_function GO:0004767 sphingomyelin phosphodiesterase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR008139Saposin B type domainSMARTSM00741sapb_4coord: 44..122
e-value: 1.6E-4
score: 31.0
IPR008139Saposin B type domainPROSITEPS50015SAP_Bcoord: 42..126
score: 12.7
NoneNo IPR availableGENE3D1.10.225.10coord: 41..118
e-value: 1.6E-5
score: 24.9
NoneNo IPR availableCDDcd00842MPP_ASMasecoord: 159..455
e-value: 1.92401E-123
score: 367.395
IPR011160Sphingomyelin phosphodiesterasePIRSFPIRSF000948Sphingomyelin_Pdiesterasecoord: 18..577
e-value: 4.0E-185
score: 614.6
IPR004843Calcineurin-like phosphoesterase domain, ApaH typePFAMPF00149Metallophoscoord: 158..420
e-value: 2.4E-18
score: 67.3
IPR029052Metallo-dependent phosphatase-likeGENE3D3.60.21.10coord: 156..476
e-value: 6.9E-32
score: 110.3
IPR029052Metallo-dependent phosphatase-likeSUPERFAMILY56300Metallo-dependent phosphatasescoord: 156..467
IPR011001Saposin-likeSUPERFAMILY47862Saposincoord: 43..117

Blast
BLAST of TCONS_00009740-protein vs. Swiss-Prot (Human)
Match: ASM (Sphingomyelin phosphodiesterase OS=Homo sapiens GN=SMPD1 PE=1 SV=4)

HSP 1 Score: 397.897 bits (1021), Expect = 2.090e-131
Identity = 204/538 (37.92%), Postives = 297/538 (55.20%), Query Frame = 0
Query:   21 PIKKDHNLHTFKSIFQNLGAHSSTGCTICKGLVEILHGVGSTGLGEGELINIATKICLKAKIEDNNVCNSVTREFADELWYVLMDAALQPEKVCGWIFGDSCLHYVDYFPSWNITIPPRTRPATNSWKTQKSNVNPKKILHFSDTHIDFDYLQGSNAVCNEPLCCRPVNGKAGPNDTAAPKWGFPGNCDANPLLVNNLFNHIALAHEDAEYIYWTGDVPAHNVWNQSREDQIFTIKQATKLLVQYFPHKKVFPALGNHEGAPVNSFPPPYITGQQSLSWLLDTLAEDWTTWLPKDTEETIRRGGFYTVLVEEGFRVISLNMNYGNEGNWWLWINSKDPAGQLQWLADTLYKAEQNNEKVHILGHIPPSGTLLWFRFNYYRIVDRFHDTIAAQFFGHTHHDEFSLFYHSDDTEVPNNIAYIGPSVTTYNNMNPGYRTYDVDGSTTNATWNVINHDTFYAEIQKTDDTHP-PEWLHEYNAKEAYGMKDLSPGQWHSLIQRMYNDPELFQIMFKAYRKQYKYDTCDTLKCRRSFLCGMMDG 557
            P      LH      +++    +  C ICKGL   ++           + ++A K+C   KI    VC S+   F D++  V   + L P + CG + G +C H+ D F SWNI++P   +P               +IL  +D H D DYL+G++  C +PLCCR  +G    +   A  WG    CD     + +L + +  A    + +YWTGD+PAH+VW+Q+R+DQ+  +   T L+ ++     V+PA+GNHE  PVNSFPPP+I G  S  WL + +A+ W  WLP +   T+R GGFY +    G R+ISLNMN+ +  N+WL INS DPAGQLQWL   L  AE   +KVHI+GHIPP   L  + +NYYRIV R+ +T+AAQFFGHTH DEF +FY  +    P  +A++ PS TTY  +NPGYR Y +DG+ + ++  V++H+T+   + + +     P W   Y A+E YG+ +  P  WH+L+ RM  D +LFQ  +  Y K +         CR + LC  +  
Sbjct:   64 PQGHPARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGHW-DIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSSRWLYEAMAKAWEPWLPAEALRTLRIGGFYALSPYPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPGHCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETLSRPLAVAFLAPSATTYIGLNPGYRVYQIDGNYSGSSHVVLDHETYILNLTQANIPGAIPHWQLLYRARETYGLPNTLPTAWHNLVYRMRGDMQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSA 599          
The following BLAST results are available for this feature:
BLAST of TCONS_00009740-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ASM2.090e-13137.92Sphingomyelin phosphodiesterase OS=Homo sapiens GN... [more]
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