DNA replication licensing factor (polypeptide) - C. hemisphaerica

Overview
NameDNA replication licensing factor
Unique NameTCONS_00072983-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length774

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00072983-protein ID=TCONS_00072983-protein|Name=DNA replication licensing factor|organism=Clytia hemisphaerica|type=polypeptide|length=774bp
MPSQGTPKPSKKRNRSTTSPGSERSRRSSRLSSNLSEEQPSDPVEAPTKQ
RKTEDKPSSPLPLAPTSPNVSQNEHDRSGDHDRSLLSRTGLLNTSEIDLS
SPLNYGTPASSRLGSMAVGTPRGTPVRLRSDIQSTRKLKQVNVGGGSEPT
DNNDPVVSSEAPAEPKLVIWGTDVVVSETKERFRQFILNFKDDTVEEYDP
DQALYMQKLDEISITEKPFFNVDCLHLKAYHAELYRQLVCYPQEVIPTFD
MAVNEVFNENHENIELEHQIQVRTFNVDKTMNMRSLNPEDIDQMITISGM
IIRTSNIIPEMRESFFQCHVCRATRTVEIDRGTINEPTSCANCNTQQSMM
LVHNRSQFTDKQMIKMQESPDDMPAGQTPHTVIMYGYGDLVDSVQPGDRV
TVTGIYRATPLRVNPRMRNVKSVYKTYIDVIHFRKTDKKKLHERDADSQV
AFTPERVEYLKELSAMPDIYERLARALAPSIYENIDIKKGILLQLFGGTF
KDFTAAGRGKFRSDINILLCGDPGTSKSQLLQYVHNLVPRGQYTSGKGSS
AVGLTAYVTRDPETNQLVLQTGALVLSDNGICCIDEFDKMSEGTRSVLHE
VMEQQTLSIAKAGIICQLNARTSILAAANPQKSQWDPNLTTVENIQLPHT
LLSRFDLIFLILDPQDEHFDRRLATHLVSLYHMSEQEADEEDVDMSTLRD
YLAYAKNNVSPKLNDEASQTLISSYVEMRKAGSNRGAVSAYPRQLEALIR
LAEAHARMRFSNVVDIVDVEEAKR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_045266XLOC_045266Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00072983TCONS_00072983Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR008047MCM_4
IPR001208MCM_dom
IPR003593AAA+_ATPase
IPR031327MCM
IPR027925MCM_N
IPR033762MCM_OB
IPR018525MCM_CS
IPR012340NA-bd_OB-fold
IPR027417P-loop_NTPase
Vocabulary: Molecular Function
TermDefinition
GO:0003677DNA binding
GO:0005524ATP binding
GO:0003678DNA helicase activity
Vocabulary: Cellular Component
TermDefinition
GO:0042555MCM complex
Vocabulary: Biological Process
TermDefinition
GO:0006270DNA replication initiation
GO:0006260DNA replication
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006260 DNA replication
biological_process GO:0006270 DNA replication initiation
cellular_component GO:0042555 MCM complex
molecular_function GO:0005524 ATP binding
molecular_function GO:0003677 DNA binding
molecular_function GO:0003678 DNA helicase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR008047Mini-chromosome maintenance complex protein 4PRINTSPR01660MCMPROTEIN4coord: 353..365
score: 74.36
coord: 633..650
score: 61.11
coord: 485..496
score: 84.03
coord: 305..318
score: 66.07
IPR001208MCM domainPRINTSPR01657MCMFAMILYcoord: 572..586
score: 75.77
coord: 624..636
score: 52.36
coord: 651..659
score: 78.85
coord: 600..613
score: 80.88
coord: 512..527
score: 67.54
IPR001208MCM domainPFAMPF00493MCMcoord: 458..773
e-value: 1.2E-130
score: 435.4
IPR001208MCM domainPROSITEPS50051MCM_2coord: 469..677
score: 92.536
IPR003593AAA+ ATPase domainSMARTSM00382AAA_5coord: 513..665
e-value: 0.0029
score: 26.9
IPR031327Mini-chromosome maintenance proteinSMARTSM00350mcmcoord: 279..774
e-value: 1.9E-279
score: 944.3
NoneNo IPR availableGENE3D3.40.50.300coord: 436..661
e-value: 1.0E-15
score: 57.3
NoneNo IPR availableGENE3D3.30.1640.10coord: 169..280
e-value: 1.8E-22
score: 79.2
NoneNo IPR availableGENE3D2.40.50.140coord: 281..435
e-value: 8.1E-48
score: 161.6
NoneNo IPR availableGENE3D1.10.8.300coord: 668..774
e-value: 0.0018
score: 18.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..85
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 98..160
NoneNo IPR availableCDDcd00009AAAcoord: 516..661
e-value: 1.03131E-6
score: 46.7555
IPR027925MCM N-terminal domainPFAMPF14551MCM_Ncoord: 180..276
e-value: 9.5E-18
score: 64.6
IPR033762MCM OB domainPFAMPF17207MCM_OBcoord: 283..409
e-value: 1.9E-39
score: 134.3
IPR018525Mini-chromosome maintenance, conserved sitePROSITEPS00847MCM_1coord: 580..588
IPR012340Nucleic acid-binding, OB-foldSUPERFAMILY50249Nucleic acid-binding proteinscoord: 182..430
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 480..773

Blast
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BLAST of DNA replication licensing factor vs. Swiss-Prot (Human)
Match: MCM4 (DNA replication licensing factor MCM4 OS=Homo sapiens GN=MCM4 PE=1 SV=5)

HSP 1 Score: 976.082 bits (2522), Expect = 0.000e+0
Identity = 485/744 (65.19%), Postives = 585/744 (78.63%), Query Frame = 0 
Query:   42 DPVEAPTKQRKTEDKPSS-PLPLAPTSPNVSQNEHDRSGDHDRSLLSRTGLLNTSEI----DLSSPLNYGTPASSRLGSMAVGTPRGTPVRLRSDIQSTRKLKQVNVGGGSEPTDNNDPVVSSEAPAEPKLVIWGTDVVVSETKERFRQFILNFKDDTVEE-----YDPDQALYMQKLDEISITEKPFFNVDCLHLKAYHAELYRQLVCYPQEVIPTFDMAVNEVFNENHENIELEHQIQVRTFNVDKTMNMRSLNPEDIDQMITISGMIIRTSNIIPEMRESFFQCHVCRATRTVEIDRGTINEPTSCANCNTQQSMMLVHNRSQFTDKQMIKMQESPDDMPAGQTPHTVIMYGYGDLVDSVQPGDRVTVTGIYRATPLRVNPRMRNVKSVYKTYIDVIHFRKTDKKKLHERDADS-QVAFTPERVEYLKELSAMPDIYERLARALAPSIYENIDIKKGILLQLFGGTFKDFTAAGRGKFRSDINILLCGDPGTSKSQLLQYVHNLVPRGQYTSGKGSSAVGLTAYVTRDPETNQLVLQTGALVLSDNGICCIDEFDKMSEGTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPQKSQWDPNLTTVENIQLPHTLLSRFDLIFLILDPQDEHFDRRLATHLVSLYHMSEQEADEEDVDMSTLRDYLAYAKNNVSPKLNDEASQTLISSYVEMRKAGSNRGAVSAYPRQLEALIRLAEAHARMRFSNVVDIVDVEEAKR 774
            D   +P+++R+ ED  S+  L   PTSP V      +S      L S    +++S I    D+SSPL YGTP+S   G+   G  RGTPVR R D+ S +K  QV++       ++   +V+SE     KLVIWGTDV V+  KE F++F+  F D   +E      D  + LYMQ+L EI++  +PF NV+C H+K++   LYRQL+ YPQEVIPTFDMAVNE+F + + +  LEHQIQVR FN  KT NMR+LNPEDIDQ+ITISGM+IRTS +IPEM+E+FFQC VC  T  VE+DRG I EP+ C  C+T  SM L+HNRS F+DKQMIK+QESP+DMPAGQTPHTVI++ + DLVD VQPGDRV VTGIYRA P+RVNPR+ NVKSVYKT+IDVIH+RKTD K+LH  D ++ Q  F+ +RVE LKELS  PDIYERLA ALAPSIYE+ DIKKGILLQLFGGT KDF+  GRGKFR++INILLCGDPGTSKSQLLQYV+NLVPRGQYTSGKGSSAVGLTAYV +DPET QLVLQTGALVLSDNGICCIDEFDKM+E TRSVLHEVMEQQTLSIAKAGIICQLNARTS+LAAANP +SQW+P  TT+ENIQLPHTLLSRFDLIFL+LDPQDE +DRRLA HLV+LY+ SE++A+EE +DM+ L+DY+AYA + + P+L++EASQ LI +YV+MRK GS+RG VSAYPRQLE+LIRLAEAHA++R SN V+ +DVEEAKR
Sbjct:   28 DARSSPSQRRRGEDSTSTGELQPMPTSPGVDL----QSPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSRVEGTPRSGV-RGTPVRQRPDLGSAQKGLQVDLQSDGAAAED---IVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKR 763
The following BLAST results are available for this feature:
BLAST of DNA replication licensing factor vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MCM40.000e+065.19DNA replication licensing factor MCM4 OS=Homo sapi... [more]
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