TCONS_00072678-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00072678-protein vs. Swiss-Prot (Human)
Match: VP13A (Vacuolar protein sorting-associated protein 13A OS=Homo sapiens GN=VPS13A PE=1 SV=2)

HSP 1 Score: 758.829 bits (1958), Expect = 0.000e+0
Identity = 517/1518 (34.06%), Postives = 810/1518 (53.36%), Query Frame = 0

Query: 2173 ETSEENADIITTRQ-----EELVLDVQGISLRVEGYLGGVLTPMLKMDSKITANLKDWSSQMNAHATVSLEASYYNENVAEWEPVIEPLMEKRRE--RPWQLSVNYTMEGDDNSASSTSNELVLQKPE--SNLKIKSQDNLELTISKSCLALLGELGQVFGDAV--ESVDVLPQVLVEKEPFMIENLLSKKVTVTLNELLQGPNGDSTIELASSSNPVGITFAPKKFEKRKTNDLYT--INLSVDGF--------HDIKDIVVQRKRSVIYDLVPIKLLSAQSSYSIVVQVKTTDGQRIIVLRSPLQLKNHFPMPLDVSYISKENQPVKLTTVGSGDIYSFPLLLTYHSVFHLKPAGFDYGDCTEALNWSDLKTSNEKQFS--CPSPDKSADPFYMQVVMKEE--TYSSVHGMLDCVPRYTLECFPVITLHNYLPCTINYKIKGMAKSE-SLPGGHNWPLFTVNFSDKPSIYIEIESYNNQRWEGGLTLPTKPVDSLNKPSLSFVMMSGERKME-----LGVYYQLD-GSLNITLYSPYWLLNKTGKPLVYQPAGSSIQQVHQENDVNALMMLVKGKH----KKAKVKVKNSESWSNEFSLDTVGSGGSLKCNGPRDRVYEIGLNISLSYFGLTKIVTFTPLRMLSNHTKYTISMAESNSKSSEWHTVNPDENIPFWP----TKLPLVNLYININGQDSVKFNPEVGKTLLLKFQNEVGGVCVDYQEKDSSSVLSFNPYFAGAAPVRLENLCKKIGMIAYKQAG-SVMGHVLTHDQSVLYTWDDPTMEQEL--ICSIVNDEASETRIKLDANDFGRMRVGDGAIYWVSFLDGLQRVLLFTDN---FKSAYCACQEQNLRPTMEVDFEIESFGLSLVNVDKRMEIGYLAIRQSKTVWEQR-KKKNRWKALPLAMCEALEEGYLNYQNRKGAVKEKVLDKEVDY--------EKMFITKPEKIKIRRTYHSGLGFKYTISPNEMRVHASISSIQLDSHVPGSTFPTVLHMVEPPKSVASENAPKPFFELSLMTRIGDKNVVNEVSYCHVLIQEMDVRVDIGFLLALMELFSHAR-ARTTEKEQYALDIGQAATKFEESAEFQAAKQDRYYVLNDFHLSPLKIHVSFSLTGG------SKDENAIASLHGNVLNLLLQSVGLAFTEIQDVQFKLACYEVHKSMQSNSQLGDGITKHYQTQAIKQLYVLVLGLDVLGNPYGLISGVGTGAKNFFYEPYQGLIQGPEEFAEGLAYGVKSLVGGTVGGVSGAVSKITGTFGKGLAALTLDEEYQQKRRENMSQRPTNLGEGLAKGGKGLVKGIVSGVTGIVTKPYEGAKNDGAGGFFKGVGKGLIGVVARPVGGVVDMASNTFDGLKSTTSGVKAIELSRVTRVFHADKVLRPFNLYEADGNKILMQCNKGEYAKKNFYITHVVDKKNYLILTQSNILYVGKNELKMGEWESVWVIEFNELKREPEVKETKIIFHIHNTDTRRSIFKKSTNTREVILESSAVADWFILKLRDAK 3628
            E S E   I  T +     E + +++  I + +E  +G    PML   S+ +   K+WSS +N H  + LE  YYNE    WEP++EPL   + E  RPW L +    +       S   E   + PE  + +   S+D L +T+SK  L +L  L + F +A    S D +  +     PFMI N L   ++V+ ++     N    I +A S            + + K ND +    +LS   F        H   D +   K  V   L  ++   +    SIV Q+ T +G + + +RSP+Q++NHF +PL V           L T    + ++ PL  +Y S   LKP   +Y  C E +++ ++  ++       C S + S + F + +V +++  T  SV+        Y +  +P I L N LP  I Y I+G+  S  +L  GH+  + T     K  +++++  Y N  W+    +  KP    N+  +SFV  +   +ME     + V+   + G   +  +SPYW++NKTG+ L Y+  G  I + H  N    ++   +  H     K ++ V +SE  SN+FS+DTVGS G++KC G +   Y++G+ I LS F +T+IVTFTP  M+ N +KY IS+AE  +   +W +++ ++ IPFWP    +KL L+ +  + +    + FN +    +LL+  NE+GG+  +    + S+V++F  Y  GAA   L N  K   ++ Y Q+  S +   L   ++V YTW DP   + L   C   + E ++    +   D     +G+  IY VSF +GLQR++LFT++   FK  Y +  E+      E+   ++  G+SLVN   + E+ Y+ I  S  VWE + KKK RWK + +   E LE  +  Y     + ++KV+  + +           M I +P  I +RR Y   L  +Y  S ++      I  IQ+ + + G+ FP V + V+PPKSV  ++APKPF ++S++ R    + ++ + Y  VLIQEMD+R+D+GF+ AL +L + A     TE E +  DI     +++ ++      Q +  +   FH+SP+K+H+S SL+ G      SK    +  +H   LNLLL+S+G   T++QDV FKLA +E++    + S L   + +HY  QAIKQ+YVL+LGLDVLGNP+GLI     G + FFYEPYQG IQGPEEF EG+A G+K+LVGG VGG++GA SKITG   KG+AA+T+DE+YQQKRRE M+++P    EG+ +GGKGLV G VSG+TGIVTKP +GA+  GA GFFKGVGKGL+G VARP GG++DMAS+TF G+K  T     +E  R  R F+ D V+RP+ L +  GN++L     G +AK  ++   +++K + L++T+  +L+V K     G+    W   F+E  +EP +   + +  I   +  +S+F      + +  ++   A W + KL++A+
Sbjct: 1701 EESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADFVKDL----APFMILNSLGLTISVSPSDSFSVLN----IPMAKSYVLKNGESLSMDYIRTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTK--VGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQIRNHFSVPLSVY-----EGDTLLGTASPENEFNIPLG-SYRSFIFLKPEDENYQMC-EGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLG-KARLHLKLLDYLNHDWKSEYHI--KP----NQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQYKADG--IHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSE-LSNQFSIDTVGSHGAVKCKGLKMD-YQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGN--DKWLSLDLEQCIPFWPEYASSKL-LIQVERSEDPPKRIYFNKQ-ENCILLRLDNELGGIIAEVNLAEHSTVITFLDYHDGAATFLLINHTKN-ELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWRCRKSHGEVTQKDDMMMPID-----LGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYES--EKAELAEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLEREFKEYTESSPS-EDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTAS---LVDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHS--LNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDGTGNQMLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTF--GQLTCEWQYSFDEFTKEPFIVHGRRL-RIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAR 3168          

HSP 2 Score: 617.461 bits (1591), Expect = 8.967e-178
Identity = 511/1832 (27.89%), Postives = 887/1832 (48.42%), Query Frame = 0

Query:    1 MVFESLVADLLNKYLGQYVKNLDASQLKIGIWGGNVVLTELELKDTALDDLDLPIKVVRGYLGKLVLSIPWKNLYTESTVVDIQDLHLVAKPNFDIKYNEEREEKSKHDKKQQQIHNIEEARQREEDKKKGAKKEESDGFAEKLATNVIKNLQVTIKNIHVRYEDSISDVNGPFSVGLTMESLTAQTTDEDFVPKIIKESVSLIHKMVKLDNLALYWNPGDELIDPSLDTKQWLEVSTKQISTHQSKPEKTKYILSPMVATKKLKLNTKPGSNLDIPKMFLNLVLEELGIIVARSQYHGVVQLIESFERMNRNQPFRKYRPHTSVLGNESIWWKYCMSSILEVDVKRRSQMWSWKHIQKHRVLCKAYKVKYKEKLKQKNPSKQILTELESMEDELNIASITIFRQLAATEVLTEQKKKG-------------TKGSFFSFFSRSK----EPEKSAANKIGDLMGDDQEKEMQKLYDAIGYTENEVITPFPKEYVAMSVESILQKLFISLIDDTDKAKEFKVLDFSLNNIIVEVFQRPSAQALKLCAKIGEMKLFGTASAQCTPLIIKNMLQGRGMEFLPLVDFIFETNPLKKPDIDQCITAICQPLEIIYDANTINHIISFFKPPEHVILQDLQDKAYSTFEDFKVSSTAGLLHAMEQRTVMDIDIDVGASHLIIPEKGSYNGCTDMLVIDFGKITMSSDPSQIRHLDPKDIE-DVNEVQSKAYDRFLLSLQALQILLVREGEDLKSAKSNVSKASSHILHPINFDGKLAKAILPQDPRLKQICVSGELSSLFVSVSDDKVSRLIKLADSIPLPQSPSHDNIDGEEKPEGLFTKALSMISLTGDNDTGVDIGGFS---IPVPTSPTSVTSD--EDEYGTPPDGSILQLQQEAGPDFSSGV--------------ANQVKVDLNFKIHKVMIAI-GLTDKALKQEKECLKFIVDDINTEVILRRWDLFVNAEVGRLVLNEMTW-GVDGEPFAIMSTPKNT--KMLKFSYRRCEFNESLNLGPSYFYSKEAQVRALHFKDEFGATDQILDVQVATLFLMLHQEALLSIMSLIYQVLEPLNKHDKEATQKIKRSLSTAGSRLSLSIEEKEKERQIQRKLANPKALEAANELKQQVGLEEEKKMRVTAHLDGVGIMICSAKVDLAQAFVKGLSAKVLMKDDLLEVKASMKDMQVQDNVGETKYKDIISMRSDEVFDLELAIYENGSSGSKQYDMSCVDTSVKLNFGQMRVVFLYRFIQDLMSFTENFEEAQKAVVEAGKAAKDKALETATDLNRHSSRVKLNVVLKAPTIIIPVGSNNELALLVDLGELRIYNTFKLLNDDQYHKKSIITDNMTIKLSNLKLLKA-LIQDGKDFLHQRAIIEPMMLQITIVRNLT-KGNHSIPDVSVQAKMPAILLSISEEDVTVALKIVQGNL--AEGESHAPKKQAKPAKQTLNVPQDRL-----ADIYEEPEDEDENRQGYLQTKLSFDLAKIDIKLYL---KPSDMTFEDEFLARTDDLLLALFTIGNLCVDGDIMSTQAMKMSVRLDTLVLDDMRPIEEHEGVKRMINYSPEPLLEEVKTSSHKRPIDNSRMIEIQFDQTSSQDKNIDIKLCNMLCIFNVEFIMVLLKTLQAAIPKDDSLQHGHSMSSLDSAAGSGGSDDEDSLEASEIVLCTGDQERPETKVSIFVHNPQIVLLADAKDVKTNALFLTTEINFQYFELRDTQKMIGAVSNTAILSTAFKNDHR-SDISTVLSLDSINLHSSSPINGKPHMSVSTTLIKLNISPKTIRTLSACAGYISNDPTDEEI-KEARKAMRDLWQIQTFTNKRPWYL 1777
            MVFES+V D+LN++LG YV +LD SQL +GIW G V L  L++K+ AL  LD+P KV  G++G L L IPWKNLYT+     +++++L+  P+  IKY+  +EEK   + KQQ++  IEEA+Q+  D+++    E+ D FAEKL T +IKNLQV I +IH+RYED I++ + P S G+++++L+ QTTD+ +VP +  E+  L+ K+++LDNL  YWN   ++   S D    L+     I      PE   ++  P+ A  KL +N +   +   PK+ L + L  + I   + QY  +++L+ES + M +N P+RK++P   +  +   WW Y +  +LEV+V  R  MWSWKHI+KHR   K YK  YK+KL  K P  ++L  LE +E  L++ +ITI RQ A  EV    KK G              KG F   +S S+    E +     +  + M   +EK +  LY+AIGY+E  V     K + A+     L+ + I L ++  K +   ++D  +      + QRP AQA+K   KI    + G       P ++ ++        + L    FE NPL +    +CI    +PLEIIYDA T+N I+ FF+PP+ V L  L     +  E+F+  +  GLL+ +E + V+D+ I++ AS++I+P+ G ++  +++L++D G + ++S  S+    D K  E ++ E+  +AYD F + L ++Q+L  R G++ + A+  +S ++ HIL P++F+ +L+KA++  D R+ +  + G+L  + + +SD K+  +++L +SIP              KPE +   +  + S      T +     S   IP+   P SV+ D  E+E+   P   +     E    F +GV               N     + F++ KV+I    L       E   ++ +V  +  E+ +R +DL  NA +    L    +   + +P  +++T  NT   +L   Y + E N                      K  +    Q++ V  ++L + LH EALL+ ++ ++ +L      +K A                +S  E E +  + +KLA          LK     E+   +++ A L  + I I   K ++++  ++GL ++++M+    E+ A ++++ V D+     YK  + +   EVF  ++  Y + ++GS   DM+ VD  V L  G + VVF+ +F+  +++F +NF+ A++A+ EA   A   A     +L + SSR+ L++ +KAP ++IP    +E   + D G + + NTF ++ + Q     +I D +TIKLS ++L ++  I D   +     ++ P+ L++ + RNL  +    +P  +V A++  +   +S+ED+T   K + GN+   +  S +P         T  V  +       A +      E  +R   ++T L+      D+ + L    P   +F D    R   L LA F + N+     + +  +   S  L   +LDD RP    +   RMI  +                 D   M++I++ +            C    +F   +I   ++ LQ             +++++   A + G+  E S++          QE  + ++++ + NP+IV +AD       AL +TT+    Y    +   M  A+ +  + +  F    R   I+TVL    +   ++        + +S   + L +SP  I T+      +    T E I +E   +   LW+ +     + W+L
Sbjct:    1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLP-EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLS-DYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEV----KKAGYKIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKAL--LYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPE---LVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSSLDDA-----MSLFQITFEINPLDETVSQRCIIE-AEPLEIIYDARTVNSIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSK-SRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREAR-KLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIP--------------KPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELP-SVSEDDSEEEFFDAPCSPL-----EEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGDC---ELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKN------------------VPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILP--QSEEKSA---------------PVSTTETEDKGDVIKKLA----------LKLSTN-EDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVI-DLITIKLSEMRLYRSRFINDA--YQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTD---VRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRP-HVKKATPRMIGLT--------------VGFDKKDMMDIKYRKVRDG--------CVTDAVFQEMYICASVEFLQ-------------TVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKNPEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYT--TKETIPEETASSTAHLWEKKDTKTLKMWFL 1700