TCONS_00071693-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00071693-protein
Unique NameTCONS_00071693-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length486

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00071693-protein ID=TCONS_00071693-protein|Name=TCONS_00071693-protein|organism=Clytia hemisphaerica|type=polypeptide|length=486bp
TQRSMNLKILKSNDVYVLTICLILVVGSGANFSNGTGNITRGKSLTDIYD
KIFGESANYKPEVKASQEEGRRRLDVIFDINIRTILGLEVKTQTFHLTAV
IHMRWKDKRLTWNESEFDGIDTLNVGNSIVWTPDIMLYNDVNEETLSHTE
IFRSKVLIQNDGTVIWTNPVTIKSTCQVDVTWFPVDYQVCNLTFGSWSYS
EQVMNIKFRNKKKDRDMIKSDFHIPSGEWSMEEIKFFEEEKTFECCKNPF
SVITLQVFMKRYPDFYYLYVFLPFISQIILFLLIFHIHPDQGDRLSYGVA
LLLNMTMYMIFLSDKLPEKSDSVPYVGALFVTFFFLLSIALVLSAVTMHC
STRDTPLPMIAHKVKAITNRIWPCGKKSNARSKSSKYGSYNMKLRKPKSE
TDSNFNDPRGPKGDANRKVSDLIESDSESSSVEIARNDKYENRFEGWFEF
MRFTEKWLTVIFAFLLVVIPIIIAGSVNTRMTQPDY
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_044535XLOC_044535Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00071693TCONS_00071693Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006029Neurotrans-gated_channel_TM
IPR006202Neur_chan_lig-bd
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 96..112
score: 29.01
coord: 176..190
score: 47.03
coord: 129..140
score: 44.19
coord: 257..269
score: 24.05
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 273..424
e-value: 2.3E-10
score: 40.9
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 263..477
NoneNo IPR availableGENE3D1.20.58.390coord: 269..484
e-value: 1.8E-20
score: 72.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 395..425
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 32..268
e-value: 1.5E-53
score: 181.0
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 47..262
e-value: 5.1E-49
score: 166.6
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 46..261
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 176..190

Blast
BLAST of TCONS_00071693-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 181.415 bits (459), Expect = 2.983e-51
Identity = 90/297 (30.30%), Postives = 157/297 (52.86%), Query Frame = 0
Query:   58 NYKPEVKASQEEGRRRLDVIFDINIRTILGLEVKTQTFHLTAVIHMRWKDKRLTWNESEFDGIDTLNVGNSIVWTPDIMLYNDVNEETLSHTEIFRSKVLIQNDGTVIWTNPVTIKSTCQVDVTWFPVDYQVCNLTFGSWSYSEQVMNIKFRNKKKDRDMIKSDFHIPSGEWSMEEIKFFEEEKTFECCKNPFSVITLQVFMKRYPDFYYLYVFLPFISQIILFLLIFHIHPDQGDRLSYGVALLLNMTMYMIFLSDKLPEKSDSVPYVGALFVTFFFLLSIALVLSAVTMHCSTRD 354
            NY P  +    + +  L V F +++  I+ ++ K Q       + M W D  L WN SE+ G+ T+   +  +W PDI+LYN  +E        F + VL+ + G   +  P   KS+C +DV WFP D Q C L FGSWSY    ++++ +             +IP+GEW +  I     E+ +ECCK P+  +T  V M+R   +Y L + +P +    L LL+F +  D G+++S G+ +LL++T++M+ +++ +P  SDSVP +   F +   ++ +++V++ + +     D
Sbjct:   36 NYNPLERPVANDSQP-LTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADER---FDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISG-------YIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHD 321          
The following BLAST results are available for this feature:
BLAST of TCONS_00071693-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACHA72.983e-5130.30Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
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