TCONS_00071687-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00071687-protein
Unique Name	TCONS_00071687-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1634

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00071687-protein ID=TCONS_00071687-protein|Name=TCONS_00071687-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1634bp
MSEDDKNKNNSNSENLDAAVEGDQPHNDSVREITQQEKEILNSQSKTFTK
CHGGNTHVWKLDGEICSVFSDIQVKTIAFGSEHCLVLTEDHNIYTYGSNT
HGQLGQGDCEERKELCLIDNLSENTIHHISCGERHNVVLDDAGILYTWGD
STHGQCGLGCTGIFPKPQRVRFLPTRNMSLKKEISPENFIETLIRDVSCG
EVFSVAIDTKGCIWSWGSGCALGHGQDYEISTSPKLLKSLSNKKAIFLSC
GAYHCVVITQDEFIDDMLNIPSSPDYRTASVSSNYYSELKAKKVSSAMAN
LQQSTMLSTTAEMSPIFEPKHSKSESALKEKAQTNTIDFEPSNSINNQKK
EGPGDTDSIASSRDESLSSSQFYSASDISSLESPIQSQHWEEKETNDDKS
LEKLSSSSSIDKDGEITPLQNKDNEIFSGKKAFFSEENIQESESPIPGRS
RSSEVVTRKISLPTFNSAISIDDTLNTNLFEMSTSTQVWTFGKNSYGQLG
HGDVEDRFVPTLVEKLGCKGIIKVAAGSYHTLLLSSQGKVYSCGDNAFGQ
LGQMKTMMKLPKKVKVLDGVRVWDFAAGRNFSLFLGDSDRNKSDVFFCGD
GVEHRNNVTQRRSSISEPIIEISHLEKRSKWRLSSRKKTAPARSTSPNMI
DIKLRKITHFQEKELIKLVTAKDYSFACISQSFSHELLLEPIYKFARAER
LIYQQMMTIQKVVIEPFISTDAWNNLSKQIAGDALLLLIDSFVDLLNGIS
TELMNLSEIIRKSLPVQDLFSYVFSDSFRTVYERYAKCYADALAVGLIQM
AVKPCNNIISKRKELMKNLEKQLSLTQANFESLLKVPLLRCHVYCDLAKR
LSTHCQGENETKQLKEVIQRWLVFSESSISKLTLANATNSFWNDSHTKLI
ETLKEPSRRVLKSSKTDPLTLARASRLSSHSYILCNNVFVHVQYNRTFQT
FPLVTLWADAENDTEHTHNAIKVTTPEESFVLVAGTPDGKLAWLKELNQA
IALALAASSQQGVDIGSVNSSGLLLAAVAREATYTYQNHMTYRQATYVGM
WMSGQPHGRGRMNWEDGMWYEGEFVQGRFEGFGQMFFPKNATNLTEKTYE
GEWKEGKMFGYGKMNYGQNEEYTGYFKENARHGHGTLKYSSNKTSLDTIY
VGDWINDMKFGYGVIDYIIRGEKYMGMWSNDQRQGFGVVVTVDGVYYEGK
FIQNRLAGRGILLSEDDTRYEGEFTADMLLNGKGILTMPNGDFIDGSFYG
TWGENIKVNGTFSKFSNPRTTGIPHSASDLDRLRNTDFTIHADTKWQSLF
NECLYQLGCQSPGDDVTPDKAWRSVYDHVLKAAGSLSTIRGTNARIDYEF
IRNNEYKETMNLAHNLKGLKEFLSQAFDIFGHPLHTLVEGLSDVYRATYV
GVGAHRRLLPHAVNEAKSYVTRLFKLLRILFPDLHDEEFVFLSNETVDGY
TDPPVNSMSLLHPLLLPRLYPPLFTLYALQTEKTDAEYIEKLHYLNKRSD
IALMSYLEIKRDFWLLPPDIDPDDTDIKHEAYKEAIDTLGQISTMYSPME
KIDVLMKTFDKIHEEVENYFKTLASAQGKVKMLSMDDLLPIFHFILIRAR
IPHLGSEIQFIDDMVGQGISHGEASHRFTTLSVC

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_044530	XLOC_044530	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00071687	TCONS_00071687	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR003409	MORN
IPR011993	PH_dom-like
IPR000408	Reg_chr_condens
IPR003123	VPS9
IPR009091	RCC1/BLIP-II
IPR000219	DH-domain

Vocabulary: **Biological Process**
Term	Definition
GO:0035023	regulation of Rho protein signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005089	Rho guanyl-nucleotide exchange factor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035023	regulation of Rho protein signal transduction
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 809..836
None	No IPR available	GENE3D	2.130.10.30		coord: 265..661 e-value: 5.8E-37 score: 127.0
None	No IPR available	GENE3D	2.130.10.30		coord: 1..264 e-value: 1.3E-50 score: 171.9
None	No IPR available	GENE3D	1.20.900.10		coord: 681..877 e-value: 8.8E-4 score: 18.5
None	No IPR available	GENE3D	2.20.110.10		coord: 1100..1178 e-value: 1.1E-13 score: 51.1 coord: 1029..1099 e-value: 6.0E-10 score: 39.0 coord: 1179..1287 e-value: 1.2E-14 score: 54.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 320..422
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..27
None	No IPR available	SUPERFAMILY	109993	VPS9 domain	coord: 1372..1632
None	No IPR available	SUPERFAMILY	82185	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	coord: 1044..1143
None	No IPR available	SUPERFAMILY	82185	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	coord: 1121..1249
IPR003409	MORN motif	SMART	SM00698	morn	coord: 1120..1141 e-value: 0.1 score: 21.6 coord: 1097..1118 e-value: 1.2 score: 13.5 coord: 1148..1169 e-value: 41.0 score: 2.0 coord: 1218..1240 e-value: 12.0 score: 5.9 coord: 1045..1066 e-value: 0.097 score: 21.7 coord: 1172..1193 e-value: 0.17 score: 19.8 coord: 1070..1089 e-value: 1.4 score: 13.1
IPR003409	MORN motif	PFAM	PF02493	MORN	coord: 1070..1090 e-value: 0.015 score: 15.0 coord: 1220..1242 e-value: 4.9 score: 7.1 coord: 1099..1115 e-value: 0.076 score: 12.9 coord: 1122..1142 e-value: 0.0044 score: 16.7 coord: 1047..1067 e-value: 0.015 score: 15.1 coord: 1174..1194 e-value: 0.024 score: 14.4 coord: 1150..1167 e-value: 0.61 score: 10.0
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 898..1014 e-value: 5.5E-7 score: 28.9
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 933..1002
IPR000408	Regulator of chromosome condensation, RCC1	PFAM	PF00415	RCC1	coord: 90..139 e-value: 7.3E-8 score: 32.8 coord: 143..207 e-value: 2.4E-8 score: 34.4 coord: 487..534 e-value: 9.9E-13 score: 48.4 coord: 210..258 e-value: 2.4E-5 score: 24.8 coord: 538..585 e-value: 2.0E-7 score: 31.4
IPR000408	Regulator of chromosome condensation, RCC1	PROSITE	PS00626	RCC1_2	coord: 524..534
IPR000408	Regulator of chromosome condensation, RCC1	PROSITE	PS50012	RCC1_3	coord: 143..210 score: 11.167
IPR000408	Regulator of chromosome condensation, RCC1	PROSITE	PS50012	RCC1_3	coord: 211..261 score: 11.308
IPR000408	Regulator of chromosome condensation, RCC1	PROSITE	PS50012	RCC1_3	coord: 538..588 score: 11.368
IPR000408	Regulator of chromosome condensation, RCC1	PROSITE	PS50012	RCC1_3	coord: 486..537 score: 15.067
IPR000408	Regulator of chromosome condensation, RCC1	PROSITE	PS50012	RCC1_3	coord: 91..142 score: 12.072
IPR003123	VPS9 domain	PFAM	PF02204	VPS9	coord: 1533..1632 e-value: 7.4E-16 score: 58.2
IPR003123	VPS9 domain	PROSITE	PS51205	VPS9	coord: 1497..1634 score: 26.158
IPR009091	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	SUPERFAMILY	50985	RCC1/BLIP-II	coord: 69..262
IPR009091	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	SUPERFAMILY	50985	RCC1/BLIP-II	coord: 485..604
IPR000219	Dbl homology (DH) domain	SUPERFAMILY	48065	DBL homology domain (DH-domain)	coord: 703..870

Blast

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BLAST of TCONS_00071687-protein vs. Swiss-Prot (Human)
Match: ALS2 (Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=2)

HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0
Identity = 429/1227 (34.96%), Postives = 636/1227 (51.83%), Query Frame = 0

Query:  451 RSSEVVTRKISL-PTFNSAISIDDTLNTNLFEMSTSTQVWTFGKNSYGQLGHGDVEDRFVPTLVEKLGCKGIIKVAAGSYHTLLLSSQGKVYSCGDNAFGQLGQMKTMMKLPKKVKVLDGVRVWDFAAGRNFSLFLGDSDRNKSDVFFCG--DGVEHRNNVTQRRSSISEPIIEISHLEKRSKWRLSSRKKTAPARSTSPNMIDIKLRKITHFQEKELIKLVTAKDYSFACISQSFSHELLLEPIYKFARAERLIYQQMMTIQKVVIEPFISTDAWNNLSKQIAGDALLLLIDSFVDLLNGISTELMNLSEIIRKSLPVQDLFSYVFSDSFRTVYERYAKCYADALAVGLIQMAVKPCNNIISKRKELMKNLEK---QLSLTQANFESLLKVPLLRCHVYCDLAKRLSTHCQ-GENETKQLKEVIQRWLVFSESSISKLTLANATNSFWNDSHTKLIETLKEPSRRVLKSSKTDPLTLARASRLSSHSYILCNNVFVHVQYNRTFQTFPLVTLWADAENDTEHTHNAIKVTTPEESFVLVAGTPDGKLAWLKELNQAIALALAASSQQGVDIGSVNSSGLLLAAVAREATYTYQNHMTYRQATYVGMWMSGQPHGRGRMNWEDGMWYEGEFVQGRFEGFGQMFFPKNATNLTEKTYEGEWKEGKMFGYGKMNYGQNEEYTGYFKENARHGHGTLKYSSNKTSLDTIYVGDWINDMKFGYGVIDYIIRGEKYMGMWSNDQRQGFGVVVTVDGVYYEGKFIQNRLAGRGILLSEDDTRYEGEFTADMLLNGKGILTMPNGDFIDGSFYGTWGENIKVNGTFSKFSNPRTTGIPHSASDLDRLRN----TDFTIHADTKWQSLFNECLYQLGCQSPGDDVTPDKAWRSVYDHVLKAAGSLSTIRGTNARIDYEFIRNNEYKETMNL-----------AHNLKGLKEFLSQAFDIFGHPLHTLVEGLSDVYRATYVGVGAHRRLLPHAVNEAKSYVTRLFKLLRILFPDLHDE------------EFVFLSNETVDGYTDPP-----VNSMSLLHPLLLPRLYPPLFTLYALQTEKTDAEYIEKLHYLNKRSDIALMSYLEIKRDFWLLPPDIDPDDTDI----KHEAYKEAIDTLGQISTMYSPMEKIDVLMKTFDKIHEEVENYFKTLASAQGKVKMLSMDDLLPIFHFILIRARIPHLGSEIQFIDDMVGQGISHGEASHRFTTLSVC 1634
            +++ V TR + L PT++      D L  +L      T+VWT+GK   GQLGHGDV  R  P  V+ L  K +I + AG YH+L L+++ +VYS G N FGQLG       +P+  K+     VW  AAGR++SLFL D++  +  +++ G  D  E  +N+ +  S    P++            LS  K    +R T+                         KD   A + ++      +  +++ A  ER  Y ++  I+  ++ P +S +   NL        L  +   F  L   I     +LS  +      + L     S  F   Y  Y     + L +G  Q+  KP  + ++K +EL+++L +   + +       +L  +P+ R H Y  +  +L+T  +    E ++L++    +   +     K   A  T  FW     K+ ++L++P RR+L  S    L+L  A R S + +IL N+  VH Q++ T   FPL TLWA+  ++     N +K+TTPEE F L++ TP  K  WL+ ++QA+  AL   S      GS +S       ++R A YT+      + ATY G W+SG+PHGRG + W DG  Y G F  G  +G+G+   P  A N  E  Y G WKEGKM G G  +Y   E + G F++N RHGHG L+     +S  ++++G W+ D K GYGV D I RGEKYMGMW +D  QG GVVVT  G+YYEG F  N++ G G+LLSEDDT YEGEF+ D  L+GKG LTMPNGD+I+G F G WG  IK+ GT+ K S           SD DR +      +  + AD KW+++F+EC  QLGC+ PG      + W++ +D++   A +L+T R  + R   E +  ++ +   +L                 ++++L +A D   HPL  LVE L  VYR TYVGVGA+RRLL  AV E KSY+ R+F+L+R LFP+L +E            E         D  ++ P     V S  LL P+LLPRLYPPLF LYAL  ++ +  Y E +  LNK+ DIAL+ +L ++R FW     I  +   +    K   +  A++ L QIST ++P +K+ V+ +TF++I + V      LAS      + SMDDL P+F ++++RARI +LGSE+  I+D++   + HGE    FTTL  C
Sbjct:  498 KAARVKTRTVVLTPTYSGEA---DALLPSL-----RTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTEDFQPGLYYSGRQDPTEG-DNLPENHSGSKTPVL------------LSCSKLGYISRVTA------------------------GKDSYLALVDKNIMG--YIASLHELATTERRFYSKLSDIKSQILRPLLSLE---NLGTTTTVQLLQEVASRFSKLCYLIGQHGASLSSFLHGVKEARSLVILKHSSLFLDSYTEYCTSITNFLVMGGFQLLAKPAIDFLNKNQELLQDLSEVNDENTQLMEILNTLFFLPIRRLHNYAKVLLKLATCFEVASPEYQKLQDSSSCYECLALHLGRKRKEAEYTLGFWKTFPGKMTDSLRKPERRLLCESSNRALSLQHAGRFSVNWFILFNDALVHAQFS-THHVFPLATLWAEPLSEEAGGVNGLKITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGMSDL-PPYGSGSSVQRQEPPISRSAKYTFYKDPRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMN-KEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGEWGSGIKITGTYFKPS--------LYESDKDRPKVFRKLGNLAVPADEKWKAVFDECWRQLGCEGPGQ----GEVWKA-WDNI---AVALTTSRRQH-RDSPEILSRSQTQTLESLEFIPQHVGAFSVEKYDDIRKYLIKACDTPLHPLGRLVETLVAVYRMTYVGVGANRRLLQEAVKEIKSYLKRIFQLVRFLFPELPEEGSTIPLSAPLPTERKSFCTGKSDSRSESPEPGYVVTSSGLLLPVLLPRLYPPLFMLYALDNDREEDIYWECVLRLNKQPDIALLGFLGVQRKFWPATLSILGESKKVLPTTKDACFASAVECLQQISTTFTPSDKLKVIQQTFEEISQSV------LASLHEDF-LWSMDDLFPVFLYVVLRARIRNLGSEVHLIEDLMDPYLQHGEQGIMFTTLKAC 1647

HSP 2 Score: 90.1225 bits (222), Expect = 7.272e-18
Identity = 60/241 (24.90%), Postives = 113/241 (46.89%), Query Frame = 0

Query:   41 LNSQSKTFTKCHG----GNTHVWK-----LDGEICSVFSDIQVKTIAFGSEHCLVLTEDHNIYTYGSNTHGQLGQGDCEERKELCLIDN-LSENTIHHISCGERHNVVLDDAGILYTWGDSTHGQCGLGCTGIFPKPQRVRFLPTRNMSLKKEISPENFIETLIRDVSCGEVFSVAIDTKGCIWSWGSGCALGHGQDYEISTSPKLLKSLSNKKAIFLSCGAYHCVVITQDEFIDDMLNIP 271
            ++S+ ++ T+  G    G  H+W+     +  E    +    V   A G +H ++LTED  +Y++G+        G  E      +++N L    +  ++ G  H+  + D G+ Y WG+++ GQC +      P+P  V    +       E SP   +   I  ++CGE  ++A+     IW+WG+GC LG        T P+ ++ L+ +  + ++CGA+H + + Q     D+  +P
Sbjct:    1 MDSKKRSSTEAEGSKERGLVHIWQAGSFPITPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLP---WRSGPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADS-------EASP--LLAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQCLPSQDLKPVP 229

The following BLAST results are available for this feature:

BLAST of TCONS_00071687-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00071687-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
ALS2	7.272e-18	34.96	Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=2	[more]

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TCONS_00071687-protein (polypeptide) - C. hemisphaerica

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