TCONS_00071059-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00071059-protein
Unique NameTCONS_00071059-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length985

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00071059-protein ID=TCONS_00071059-protein|Name=TCONS_00071059-protein|organism=Clytia hemisphaerica|type=polypeptide|length=985bp
MENNLLEEEGEDYLTQYDVELYLKKNPQFAKQFVYTYLKNNLDVADEFFQ
AWYDNMIGLSLKRVSRRDRGAPPHDRNHVKSNFNTNPVDEPQCIMGDIET
EPRDHKSYNNNVLPNMKHAYLENNANRRRSDPVNNDVKKLCYGSDECLDT
IEEDLITRTSRSNSVVLPQETRYRTISMDENNNSLQKAIELLQLPAISTD
TQQKPHLRKAQSAPTYKKNLSNLIRSSVYSGSGVSKHINVENHTGLRDSN
ESHYLVEIIKDISKDMSLTKVCFKILVNLGFLLNTEKASIFLVHMDGENG
FLKLLLNDVSIAKGVRKESLSSSVSKQPQSIPIGSGIVGHVAENGQSLIV
NDISKFSEYHPIFDSWWTKNTRNALLQPVKNSEGKTIAVIVSSNNKSGEF
VDEDKQIGASFLSYCGISITNALIFELTKEEFERNKMLLEFSHDIFEEQS
SLTNAIQKILNKALEMFNCKRASLMLLDDPKEVEERQVFSKLFQVTSEID
KKEKRFSKFQRDSMVFSSNFDPFSDVVADTKTLKSKNQKKMILSSTPVSS
VPAGILCEDGLISIPVRNNSSQIIGVLKLYDREDVSSTNSLSANEEQLLE
AFAIFAGLGINNCIMYDNIVKGQAHQKVALEALSYHTAARQTDVDKLKFA
SIPSCSKFHLTSFTFDDFSLLDHEMLAAAIRMFMEFGFLKKFQIDYEVLC
RFLITVKNNYRRVIYHNWRHAFNVTQSMFAMLTTGKMSEQLSSSECLALL
VGCLCHDLDHRGTNNEFQMKTDSPLQKLYGTSTMEQHHFNCAVTILNSEG
NNIFAHLQSQEYRKVMKLLKHAILATDLSNYIRQRDKFSNAVETKSLDTS
LSENRAMLRSMLMTASDLSGITKPWDIQKRVVHLVTSEFFHQGDIERDQL
HVQPKQMMDRNYILQLPKLQVNFFQFMGIPVYKVLSDYNSLLSPFLEGAK
SNKETWFEMNAEIEKGHVHPDIEPVLHPVRQEEIP
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_044146XLOC_044146Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00071059TCONS_00071059Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR023088PDEase
IPR003018GAF
IPR003607HD/PDEase_dom
IPR029016GAF_dom-like
IPR002073PDEase_catalytic_dom
IPR023174PDEase_CS
Vocabulary: Molecular Function
TermDefinition
GO:0008081phosphoric diester hydrolase activity
GO:0005515protein binding
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity
Vocabulary: Biological Process
TermDefinition
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007165 signal transduction
molecular_function GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function GO:0008081 phosphoric diester hydrolase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0230883'5'-cyclic nucleotide phosphodiesterasePRINTSPR00387PDIESTERASE1coord: 863..876
score: 56.29
coord: 880..896
score: 48.24
coord: 742..755
score: 29.29
coord: 782..798
score: 36.59
coord: 711..724
score: 59.14
coord: 756..771
score: 58.62
IPR003018GAF domainSMARTSM00065gaf_1coord: 451..620
e-value: 0.0031
score: 24.2
coord: 267..429
e-value: 8.1E-10
score: 48.6
IPR003018GAF domainPFAMPF13185GAF_2coord: 296..419
e-value: 4.8E-7
score: 30.1
IPR003607HD/PDEase domainSMARTSM00471hd_13coord: 713..881
e-value: 4.7E-8
score: 42.8
IPR029016GAF domain-likeGENE3D3.30.450.40coord: 549..618
e-value: 1.1E-6
score: 28.3
IPR029016GAF domain-likeGENE3D3.30.450.40coord: 437..515
e-value: 0.0014
score: 17.7
IPR029016GAF domain-likeGENE3D3.30.450.40coord: 246..436
e-value: 1.1E-19
score: 70.3
IPR029016GAF domain-likeSUPERFAMILY55781GAF domain-likecoord: 251..445
IPR029016GAF domain-likeSUPERFAMILY55781GAF domain-likecoord: 432..637
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainGENE3D1.10.1300.10coord: 619..969
e-value: 7.8E-106
score: 353.3
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPFAMPF00233PDEase_Icoord: 715..947
e-value: 5.7E-75
score: 252.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 67..92
NoneNo IPR availableCDDcd00077HDccoord: 715..890
e-value: 2.04372E-9
score: 55.8085
NoneNo IPR availableSUPERFAMILY109604HD-domain/PDEase-likecoord: 654..969
IPR0231743'5'-cyclic nucleotide phosphodiesterase, conserved sitePROSITEPS00126PDEASE_Icoord: 756..767

Blast
BLAST of TCONS_00071059-protein vs. Swiss-Prot (Human)
Match: PDE11 (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Homo sapiens GN=PDE11A PE=1 SV=2)

HSP 1 Score: 551.592 bits (1420), Expect = 0.000e+0
Identity = 309/778 (39.72%), Postives = 468/778 (60.15%), Query Frame = 0
Query:  199 TDTQQKPHLRKAQS-APTYKKNLSNLIRSSVYSGSGVSKHINVENHTGLRDSNESHYLVEIIKDISKDMSLTKVCFKILVNLGFLLNTEKASIFLVHMDGENGFLKLLLNDV-SIAKGVRKESLSSSVSKQPQSIPIGSGIVGHVAENGQSLIVNDISKFSEYHPIFDSWWTKNTRNALLQPVKNSEGKTIAVIVSSNN--KSGEFVDEDKQIGASFLSYCGISITNALIFELTKEEFERNKMLLEFSHDIFEEQSSLTNAIQKILNKALEMFNCKRASLMLLDDPKEVEERQV-FSKLFQVTSEIDKKEKRFSKFQRDSMVFSSNFD-----PFSDVVADT----KTLKSKNQKKMILSSTPVSSVPA-GILCEDGLISIPVRNNSSQIIGVLKLYDREDVSSTNSLSANEEQLLEAFAIFAGLGINNCIMYDNIVKGQAHQKVALEALSYHTAARQTDVDKLKFASIPSCSKFHLTSFTFDDFSLLDHEMLAAAIRMFMEFGFLKKFQIDYEVLCRFLITVKNNYRRVIYHNWRHAFNVTQSMFAMLTTGKMSEQLSSSECLALLVGCLCHDLDHRGTNNEFQMKTDSPLQKLYGTS-TMEQHHFNCAVTILNSEGNNIFAHLQSQEYRKVMKLLKHAILATDLSNYIRQRDKFSNAVETKSLDTSLSENRAMLRSMLMTASDLSGITKPWDIQKRVVHLVTSEFFHQGDIERDQLHVQPKQMMDRNYILQLPKLQVNFFQFMGIPVYKVLSDYNSLLSPFLEGAKSNKETWFEMN 960
            +  +++  LRKA S  PT    LS L+ S V         I+ + H  L+  NE  + +E++KDIS D+ LT + +KIL+ +  +++ ++ S+FLV  +G     K L++    +  G      SS+ +     +P G GI+G+V E+G+++ + D  +   ++   D      T++ L  P+++S+G+ I V  + N   +   F ++D+++   +L +CGI+I+NA +F  +++E+ER++ LLE  +D+FEEQ+ L   ++KI+++A  +  C+R S++LL+D   +E   V F+K F++ S     +   S   ++SM  SS  D       +++VA T        +    +    +  +S      +LC      +P+ N++ QIIGV ++ +R D          +++L EAF IF GLGINN IMYD + K  A Q VAL+ LSYH    + +VDK K A+IP  S+  +    FDDFSL    M+ AA+RMFME G ++KF+IDYE LCR+L+TV+ NYR V+YHNWRHAFNV Q MFAMLTT    + L+  E LA++VGCLCHDLDHRGTNN FQ K+ S L +LYGTS T+E HHFN AV IL SEG+NIFA+L S+EY  +M+LLK +ILATDL+ Y  +R +F   V     D ++  +R + RSMLMTA DL  +TKPW+I ++V  LVTSEFF QGD ER +L + P  + DRN   +LP+LQ+ +   + +P+Y+ L   N  L P L+   +N+  W E++
Sbjct:  150 SSVRRRALLRKASSLPPTTAHILSALLESRVNLPRYPPTAIDYKCH--LKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLV--EGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLED---IESPVVKFTKSFELMSPKCSADAENSF--KESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLC------VPIWNSNHQIIGVAQVLNRLD---GKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELH 909          
The following BLAST results are available for this feature:
BLAST of TCONS_00071059-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PDE110.000e+039.72Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 1... [more]
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