TCONS_00069498-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00069498-protein
Unique NameTCONS_00069498-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length365

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00069498-protein ID=TCONS_00069498-protein|Name=TCONS_00069498-protein|organism=Clytia hemisphaerica|type=polypeptide|length=365bp
SFRTSARSWKKGRTCSLRSVVCNKRGVLTTIQRLGISSSSVCQCETAPPQ
NEAESTPKEENETPQQKGTIGFIGLGNMGHHMGMNLIKDGYNLVVYDVYP
EAMKPFKELGSTAVTSPRMVAEQVTKIITMLPSSPDVFEAYNGDQGILRG
MQPDTLMIDSSTIDPSASKEVATIAADAGGTYIDAPVSGGVVAARDGALT
FMVGAKREDFEQAEILLTSMAKNVVHCGATGTGQAAKICNNMLLAVSMIG
TAEVMNMGTRLGLDKKMLAHILNISTGRCWSSELYNPCPGVIEGVPSSND
YQGGFGTQLMTKDLGLAQNASTATKSATPMGSLAHQIYRVMCNSGYAKMD
FSSVYKFLREDSFRF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_043320XLOC_043320Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00069498TCONS_00069498Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR0061156PGDH_NADP-bd
IPR011548HIBADH
IPR0133286PGD_dom_2
IPR029154NADP-bd
IPR016040NAD(P)-bd_dom
IPR0089276-PGluconate_DH_C-like
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
Vocabulary: Molecular Function
TermDefinition
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity
GO:0051287NAD binding
GO:00084423-hydroxyisobutyrate dehydrogenase activity
GO:0016491oxidoreductase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0008442 3-hydroxyisobutyrate dehydrogenase activity
molecular_function GO:0051287 NAD binding
molecular_function GO:0016491 oxidoreductase activity
molecular_function GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0061156-phosphogluconate dehydrogenase, NADP-bindingPFAMPF03446NAD_binding_2coord: 69..228
e-value: 1.5E-45
score: 155.1
NoneNo IPR availableGENE3D3.40.50.720coord: 47..239
e-value: 9.3E-32
score: 109.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 43..67
IPR0115483-hydroxyisobutyrate dehydrogenaseTIGRFAMTIGR01692TIGR01692coord: 72..359
e-value: 2.5E-123
score: 409.0
IPR0133286-phosphogluconate dehydrogenase, domain 2GENE3D1.10.1040.10coord: 240..360
e-value: 6.3E-32
score: 109.9
IPR0291543-hydroxyisobutyrate dehydrogenase, NAD-binding domainPFAMPF14833NAD_binding_11coord: 231..358
e-value: 7.0E-33
score: 113.4
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 69..229
IPR0089276-phosphogluconate dehydrogenase C-terminal domain-likeSUPERFAMILY481796-phosphogluconate dehydrogenase C-terminal domain-likecoord: 230..360

Blast
[Close]
BLAST of TCONS_00069498-protein vs. Swiss-Prot (Human)
Match: 3HIDH (3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens GN=HIBADH PE=1 SV=2)

HSP 1 Score: 392.119 bits (1006), Expect = 1.792e-136
Identity = 185/295 (62.71%), Postives = 233/295 (78.98%), Query Frame = 0 
Query:   67 KGTIGFIGLGNMGHHMGMNLIKDGYNLVVYDVYPEAMKPFKELGSTAVTSPRMVAEQVTKIITMLPSSPDVFEAYNGDQGILRGMQPDTLMIDSSTIDPSASKEVATIAADAGGTYIDAPVSGGVVAARDGALTFMVGAKREDFEQAEILLTSMAKNVVHCGATGTGQAAKICNNMLLAVSMIGTAEVMNMGTRLGLDKKMLAHILNISTGRCWSSELYNPCPGVIEGVPSSNDYQGGFGTQLMTKDLGLAQNASTATKSATPMGSLAHQIYRVMCNSGYAKMDFSSVYKFLRED 361
            K  +GFIGLGNMG+ M  NL+K GY L++YDV+P+A K F++ G   V+SP  VAE+  +IITMLP+S +  EAY+G  GIL+ ++  +L+IDSSTIDP+ SKE+A      G  ++DAPVSGGV AAR G LTFMVG   ++F  A+ LL  M  NVV+CGA GTGQAAKICNNMLLA+SMIGTAE MN+G RLGLD K+LA ILN+S+GRCWSS+ YNP PGV++GVPS+N+YQGGFGT LM KDLGLAQ+++T+TKS   +GSLAHQIYR+MC  GY+K DFSSV++FLRE+
Sbjct:   39 KTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQFLREE 333
The following BLAST results are available for this feature:
BLAST of TCONS_00069498-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
3HIDH1.792e-13662.713-hydroxyisobutyrate dehydrogenase, mitochondrial ... [more]
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