TCONS_00068835-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00068835-protein
Unique Name	TCONS_00068835-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	506

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00068835-protein ID=TCONS_00068835-protein|Name=TCONS_00068835-protein|organism=Clytia hemisphaerica|type=polypeptide|length=506bp
FLRGISNSVQFLSNLSKFEVENEDCKMKKEITFVFIIVVLLDVVRCNDAE
LRLFEKLFTGYNNKVRPINDKSKPVNTTLDIAYVQLVQLDDREQTLISNV
WVRQNWQNDKLTWDPKDFDNITVINVHPSKVWLPDVILYNNAKSGVGAGM
MYRFKTKVSIFHNGLNKWYAPAIVRSSCSIDIKNFPFDEQKCDLEFGSWT
YNGYELDLFYANDKADTSFYLASAEFDLISAKAKRFVKRYECCPEPYPNI
IYTVHVRRQPGFFLFNVIIPSMVITFFAILTFSSPPNVGERISLAIESFL
SLSFLCMMVADSIPVNSDVSPLITNFLMVCMMLISLALVFNMISMNLTGT
KPVPRWLHTLAFVYIGPLVGYCRDTNATTNSLGRFFSSRVPSKIENKVRF
MIHKLHTQLSEKKLYYGEKMLRHLCRSEHCMPQNREEGLHEEERQNMRQI
LKRSSVENNQKFNRDFWRCIAQTVDRVCVVSFSTSFLFVSAAVLMKGYGH
QLELQK

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_042913	XLOC_042913	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00068835	TCONS_00068835	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR002394	Nicotinic_acetylcholine_rcpt
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0022848	acetylcholine-gated cation-selective channel activity
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Cellular Component**
Term	Definition
GO:0045211	postsynaptic membrane
GO:0016021	integral component of membrane

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
cellular_component	GO:0045211	postsynaptic membrane
molecular_function	GO:0022848	acetylcholine-gated cation-selective channel activity
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002394	Nicotinic acetylcholine receptor	PRINTS	PR00254	NICOTINICR	coord: 84..100 score: 33.99 coord: 118..132 score: 25.85 coord: 158..176 score: 35.61
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 178..192 score: 51.37 coord: 254..266 score: 31.36 coord: 97..113 score: 30.13 coord: 130..141 score: 47.74
None	No IPR available	GENE3D	1.20.58.390		coord: 266..502 e-value: 8.0E-29 score: 99.7
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 40..265 e-value: 9.6E-70 score: 234.0
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 52..260 e-value: 2.3E-58 score: 197.1
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 50..260
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 267..491 e-value: 2.4E-21 score: 76.8
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 260..496
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 178..192

Blast

[Close]

BLAST of TCONS_00068835-protein vs. Swiss-Prot (Human)
Match: ACHA6 (Neuronal acetylcholine receptor subunit alpha-6 OS=Homo sapiens GN=CHRNA6 PE=1 SV=1)

HSP 1 Score: 266.159 bits (679), Expect = 3.214e-83
Identity = 151/460 (32.83%), Postives = 244/460 (53.04%), Query Frame = 0

Query:   49 AELRLFEKLFTGYNNKVRPINDKSKPVNTTLDIAYVQLVQLDDREQTLISNVWVRQNWQNDKLTWDPKDFDNITVINVHPSKVWLPDVILYNNAKSGVGAGMMYRFKTKVSIFHNGLNKWYAPAIVRSSCSIDIKNFPFDEQKCDLEFGSWTYNGYELDLFYANDKADTSFYLASAEFDLISAKAKRFVKRYECCPEPYPNIIYTVHVRRQPGFFLFNVIIPSMVITFFAILTFSSPPNVGERISLAIESFLSLSFLCMMVADSIPVNSDVSPLITNFLMVCMMLISLALVFNMISMNLTGTKP----VPRWLHTLAFVYIGPLVGYCRDTNATTNSLGRFFSSRVPSKIENKVRFMIHKLHTQLSE-------KKLYYGEKMLRHLCRSEHCMPQNREEGLHEEERQNMRQILKRSSVENNQ-KFNRDFWRCIAQTVDRVCVVSFSTSFLFVSAAVLMK 496
             E RLF KLF+ YN  +RP+ + S PV    ++A  QL  +D+  Q + +N+W+R  W + KL WDP ++D I  + V   K+W PD++LYNNA   VG       KTK  + +NG+  W  PAI +SSC +DI  FPFD Q C L+FGSWTY+  E+DL     K D + +  ++E+++I A   +   +Y CC E Y +I Y+ ++RR P F+  N+IIP + I+F  +L F  P + GE+++L I   LSL+   +++ ++IP  S V PL+  +L+  M+ ++L++V  +  +N+    P    +PRW+ T+ F+ + P V   R     T   G     R  ++   K +   H     L E        +L   ++ L H  +    + +N E     E+  N  Q +  +   +N+ K   D W+ +A  VDRV +  F    +F +A + ++
Sbjct:   33 TEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VG-DFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTV-FLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHGEPRHLKECFHCHKSNELATSKRRLSH--QPLQWVVENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQ 485

The following BLAST results are available for this feature:

BLAST of TCONS_00068835-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00068835-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA6	3.214e-83	32.83	Neuronal acetylcholine receptor subunit alpha-6 OS...	[more]

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TCONS_00068835-protein (polypeptide) - C. hemisphaerica