TCONS_00067595-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00067595-protein
Unique Name	TCONS_00067595-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1069

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00067595-protein ID=TCONS_00067595-protein|Name=TCONS_00067595-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1069bp
MAFVESIVNAPMEACKSMLKSISTKLGYSSDKQYINDTSLEKVLKEKTEF
RVTKVTVKKWEVIDQIKIHFDDDTEWSYGPDCGDEDPRALIMTEGEYLTR
ATHEKLYDHESAGASVEFETNKGRVFKFAPSEIDSISLGHDSNKKTVIAD
EGYEIVCLKIHRGELIGSEQQPVPKDDLNKTHPKSWYVLAYYAEKEDADL
DNELLLEGVAPTRPFQRTRNKPNEKEDKKDESNDKVDDNDENKRQFSESG
ATLGRRKSLRKRLTSEALNINDAVAVLQRASSRDDTLDEQIPLSPLYQRS
TSSFHRSTSREAKTPTEERKRPNLCRGVSLIEDKEFFPSDAFTSIPEKQE
EPALETTKKEADNENKSRPDEEPTKDVVETTTDDNATDVSDDESDSDSDQ
EILDLDLDYYHFHDQRQTQNAWKKIKDICSKKRGRGAILVDCLRSSVTKK
TGNNKSIDHCRDMATQRGYCSSEDEDNYELFEVFYTLYESMAQKAEFLMF
ISTIFFMSLNLAVGAHKSLLEGQILTAIATDPKSINWRKMNTLEEMFCGV
FFTCDGSYLSLCRSLMLYYFTVRMSLSFFNIMNSFLMKYLSDTKTAQMGR
DLFVHALFLDKRFFDETKNIHSYMNVQSLHDLLFDTIPNIITSVARYFVV
CYYLISMDLNLGLASVFFTTFFNYFIVSYFIKRDIERWKKQVQIDRVHGQ
ISYDVFEMISTVKTFAKERYHQREYDEWFESLIQSMKKGMSWEYFRSFLE
DFIDACEYIGMIYYGYIRYTGDSGMTSSDFIGFIILYQQLHGLFCEVRDN
LMWVGRGFHDVKRCTTLRETQPKMINGTNKPENIKGEIVFKDVKFKYPSR
PKDQVLKGLNLTIKSNCMTAIVGKSGAGKSTIAKLVTRLYDPSSGSITVD
GEDLKSFDVEYFRSNLAVVDQSPELFNRPLAENIAYGMVDSDQCTYAELE
AAGKLANCDFISKFREGYYTFAGYGGNDLSGGQLQRIAIARAAIRNPKIL
ILDEATSSLDSENEKEVQEALEKLMKGRTVIVIAHRLSTIRNADNIVCMK
DGTVVEQGTHDDLMEKXHQ

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_042207	XLOC_042207	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00067595	TCONS_00067595	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR003593	AAA+_ATPase
IPR011527	ABC1_TM_dom
IPR003439	ABC_transporter-like
IPR017871	ABC_transporter_CS
IPR027417	P-loop_NTPase

Vocabulary: **Biological Process**
Term	Definition
GO:0055085	transmembrane transport
GO:0006810	transport

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Molecular Function**
Term	Definition
GO:0005524	ATP binding
GO:0042626	ATPase activity, coupled to transmembrane movement of substances
GO:0016887	ATPase activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0055085	transmembrane transport
biological_process	GO:0006810	transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0016887	ATPase activity
molecular_function	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
molecular_function	GO:0005524	ATP binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003593	AAA+ ATPase domain	SMART	SM00382	AAA_5	coord: 865..1053 e-value: 4.3E-16 score: 69.4
IPR011527	ABC transporter type 1, transmembrane domain	PFAM	PF00664	ABC_membrane	coord: 565..791 e-value: 1.6E-12 score: 47.5
IPR011527	ABC transporter type 1, transmembrane domain	PROSITE	PS50929	ABC_TM1F	coord: 550..790 score: 15.715
IPR011527	ABC transporter type 1, transmembrane domain	SUPERFAMILY	90123	ABC transporter transmembrane region	coord: 498..817
None	No IPR available	GENE3D	1.20.1560.10		coord: 481..824 e-value: 4.6E-20 score: 71.3
None	No IPR available	GENE3D	3.40.50.300		coord: 825..1069 e-value: 7.2E-73 score: 244.6
None	No IPR available	GENE3D	2.100.10.30		coord: 26..168 e-value: 6.6E-7 score: 29.2
IPR003439	ABC transporter-like	PFAM	PF00005	ABC_tran	coord: 856..1007 e-value: 5.6E-31 score: 107.8
IPR003439	ABC transporter-like	PROSITE	PS50893	ABC_TRANSPORTER_2	coord: 838..1069 score: 22.769
IPR017871	ABC transporter, conserved site	PROSITE	PS00211	ABC_TRANSPORTER_1	coord: 979..993
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	52540	P-loop containing nucleoside triphosphate hydrolases	coord: 830..1066

Blast

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BLAST of TCONS_00067595-protein vs. Swiss-Prot (Human)
Match: MDR3 (Phosphatidylcholine translocator ABCB4 OS=Homo sapiens GN=ABCB4 PE=1 SV=2)

HSP 1 Score: 259.225 bits (661), Expect = 4.033e-71
Identity = 130/239 (54.39%), Postives = 169/239 (70.71%), Query Frame = 0

Query:  829 NKPENIKGEIVFKDVKFKYPSRPKDQVLKGLNLTIKSNCMTAIVGKSGAGKSTIAKLVTRLYDPSSGSITVDGEDLKSFDVEYFRSNLAVVDQSPELFNRPLAENIAYGMVDSDQCTYAELEAAGKLANC-DFISKFREGYYTFAGYGGNDLSGGQLQRIAIARAAIRNPKILILDEATSSLDSENEKEVQEALEKLMKGRTVIVIAHRLSTIRNADNIVCMKDGTVVEQGTHDDLMEK 1066
            +KP++IKG + F DV F YPSR   ++LKGLNL ++S    A+VG SG GKST  +L+ RLYDP  G+I +DG+D+++F+V Y R  + VV Q P LF+  +AENI YG       T  E++ A K AN  +FI K  + + T  G  G  LSGGQ QRIAIARA +RNPKIL+LDEATS+LD+E+E EVQ AL+K  +GRT IVIAHRLST+RNAD I   +DG +VEQG+H +LM+K
Sbjct:  385 HKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYG---RGNVTMDEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKK 620

HSP 2 Score: 232.646 bits (592), Expect = 1.753e-62
Identity = 175/535 (32.71%), Postives = 269/535 (50.28%), Query Frame = 0

Query:  564 SLMLYYFTVRMSLSFFNIMNSFLMKYLSDTKTAQMGRDLFVHALFLDKRFFDETKNIHSYMNVQSLHD-------------LLFDTIPNIITSVARYFVVCYYLISMDLNLGLASVFFTTFFNYFIVSYFIKRDIERWKKQVQIDRVHGQISYDVFEMISTVKTFAKER-----YHQREYDEWFESLIQSMKKGMSWEYFRSFLEDFIDACEYIG--MIYYGYIRYTGDSGMTSSDFIGFIILYQQLHGLFCEVRDNLMWVGRGFHDVKRCTTLRETQPKMINGTN----KPENIKGEIVFKDVKFKYPSRPKDQVLKGLNLTIKSNCMTAIVGKSGAGKSTIAKLVTRLYDPSSGSITVD-------GEDLKSFDVEYFRSNLAVVDQSPELFNRPLAENIAYGMVDSDQCTYAELEAAGKLANCD-FISKFREGYYTFAGYGGNDLSGGQLQRIAIARAAIRNPKILILDEATSSLDSENEKEVQEALEKLMKGRTVIVIAHRLSTIRNADNIVCMKDGTVVEQGTHDDLMEK 1066
            SL+  +  +    +FF  +  F      +  T ++    F   L  D  +FD+ KN    ++ +   D             L+   I N+ T +   F+  +      L L L +V      +  +    +  + +R KK+++     G+I+ +  E I TV +  +ER     Y ++ Y  +  S+ ++   G+++   ++F+      C   G  +I  G++R+     + S+   G + L           +  L               L E QP +I+  +    KP+  +G I F +V F YP+R    VL+GL+L +K     A+VG SG GKST+ +L+ R YDP +G++ VD       G++ K  +V++ R+ L +V Q P LF+  +AENIAYG  +S   +  E+ +A K AN   FI      Y T  G  G  LSGGQ QRIAIARA IR P+IL+LDEATS+LD+E+EK VQEAL+K  +GRT IVIAHRLSTI+NAD IV  ++G V E GTH  L+ +
Sbjct:  755 SLIFLFLGIISFFTFF--LQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGW-----QLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELE---AAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSFAPDYAKAKL--------SAAHLFMLFERQP-LIDSYSEEGLKPDKFEGNITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGD-NSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQ 1269

The following BLAST results are available for this feature:

BLAST of TCONS_00067595-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00067595-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
MDR3	4.033e-71	54.39	Phosphatidylcholine translocator ABCB4 OS=Homo sap...	[more]

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TCONS_00067595-protein (polypeptide) - C. hemisphaerica

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