TCONS_00066944-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00066944-protein
Unique Name	TCONS_00066944-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	248

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00066944-protein ID=TCONS_00066944-protein|Name=TCONS_00066944-protein|organism=Clytia hemisphaerica|type=polypeptide|length=248bp
GVKTIDYAGGREHEDFINFMVDPKPPKPKQVEKDWSDEVKDVVFLEPMNF
DDFVEKEKSVLVMFYAPWCGHCKKMKPGLAEAAKIVNNANDIVGKIAAVD
CVKHSSLAGKFEVSGYPTLKYFKDGKEQFKYRGQRTKDALVDFMKSPSEQ
DSSSNQPPQKTWAEESEHIIQLNDATFTEFIRDKDVFVAFYAPWCGHCST
MKHAFFETAKKLKEDNFPAVLAAVEATQNKDLAKREGVKGYPTSMVNL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_041838	XLOC_041838	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00066944	TCONS_00066944	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR005788	Disulphide_isomerase
IPR013766	Thioredoxin_domain
IPR017937	Thioredoxin_CS
IPR012336	Thioredoxin-like_fold

Vocabulary: **Molecular Function**
Term	Definition
GO:0016853	isomerase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0045454	cell redox homeostasis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0045454	cell redox homeostasis
molecular_function	GO:0016853	isomerase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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POSITION

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00421	THIOREDOXIN	coord: 60..68 score: 63.02 coord: 68..77 score: 58.44 coord: 112..123 score: 45.05
None	No IPR available	GENE3D	3.40.30.10		coord: 154..247 e-value: 3.0E-23 score: 81.9 coord: 24..153 e-value: 3.7E-34 score: 117.4
None	No IPR available	SFLD	SFLDG00345	PDI-like	coord: 44..145 e-value: 2.2E-31 score: 102.7 coord: 169..243 e-value: 1.2E-19 score: 64.9
None	No IPR available	CDD	cd02961	PDI_a_family	coord: 170..243 e-value: 8.86825E-23 score: 88.8217
None	No IPR available	CDD	cd02997	PDI_a_PDIR	coord: 41..144 e-value: 8.82258E-40 score: 133.982
IPR005788	Disulphide isomerase	TIGRFAM	TIGR01126	TIGR01126	coord: 47..146 e-value: 8.4E-32 score: 107.6
IPR013766	Thioredoxin domain	PFAM	PF00085	Thioredoxin	coord: 169..245 e-value: 1.8E-17 score: 63.0 coord: 42..145 e-value: 1.1E-28 score: 99.1
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 21..149 score: 15.857
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 150..248 score: 11.403
IPR017937	Thioredoxin, conserved site	PROSITE	PS00194	THIOREDOXIN_1	coord: 187..205
IPR017937	Thioredoxin, conserved site	PROSITE	PS00194	THIOREDOXIN_1	coord: 61..79
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 40..147
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 162..245

Blast

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BLAST of TCONS_00066944-protein vs. Swiss-Prot (Human)
Match: PDIA5 (Protein disulfide-isomerase A5 OS=Homo sapiens GN=PDIA5 PE=1 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 3.373e-42
Identity = 98/237 (41.35%), Postives = 141/237 (59.49%), Query Frame = 0

Query:   10 GREHEDFINFMVDPKPPKPKQVEKDWSDEVKDVVFLEPMNFDDFVEKEKSVLVMFYAPWCGHCKKMKPGLAEAAKIVNNANDIVGKIAAVDCVKHSSLAGKFEVSGYPTLKYFKDGKEQFKYRGQRTKDALVDFMKSPSEQDSSSNQPPQKTWAEESEHIIQLNDATFTEFI-RDKDVFVAFYAPWCGHCSTMKHAFFETAKKLKEDNFPAVLAAVEAT--QNKDLAKREGVKGYPT 243
            G   ED + ++ +P+PP+P+  E  W+DE   V  L   +FD FV++  SVLVMF+APWCGHCKKMKP   +AA+ ++   D  G +AAVD   + +LA +F +S +PTLKYFK+G E++     RTK   +++M     Q+  +  PP+ TW E+   ++ L    F E + + K   V FYAPWC HC  +   F  TA   K+D   A  AAV+    +N+DL ++E VKGYPT
Sbjct:  246 GSTAEDIVEWLKNPQPPQPQVPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNG-EKYAVPVLRTKKKFLEWM-----QNPEAPPPPEPTWEEQQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIAC-AAVDCVKDKNQDLCQQEAVKGYPT 475

HSP 2 Score: 125.946 bits (315), Expect = 2.439e-33
Identity = 84/250 (33.60%), Postives = 131/250 (52.40%), Query Frame = 0

Query:    1 GVKTIDYAGGREHEDFINFMVDPKPPKPKQVEKDWSDE--VKDVVFLEP-MNFDDFVEKE-KSVLVMFYAPWCGHCKKMKPGLAEAAKIVNNANDIVGKIAAVDCVKHSSLAGKFEVSGYPTLKYFKDGKEQFKYRGQ-RTKDALVDFMKSPSEQDSSSNQPPQKTWAEESEHIIQLNDATFTEFIRD-KDVFVAFYAPWCGHCSTMKHAFFETAKKLK-EDNFPAVLAAVEATQNKDLAKREGVKGYPT 243
            G    +Y      +  + F+ DPK P        W ++   KDVV L+   +F   ++KE K +L+MFYAPWC  CK+M P   +AA  +     + G    V   +  ++  ++ V G+PT+ YF+ G+  F+Y     T + +V+++K+P        + P   WA+E   +  L D  F +F+++   V V F+APWCGHC  MK  F + A+ L  E +   VLAAV+AT NK LA+R  +  +PT
Sbjct:  116 GAFHTEYNRAVTFKSIVAFLKDPKGPPL------WEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAG--MNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLKNPQPPQPQVPETP---WADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPT 354

HSP 3 Score: 76.6406 bits (187), Expect = 5.437e-16
Identity = 44/112 (39.29%), Postives = 60/112 (53.57%), Query Frame = 0

Query:   42 VVFLEPMNFDDFVEKEKSVLVMFYAPWCGHCKKMKPGLAEAAKIVNNANDIVGKIAAVDCVK--HSSLAGKFEVSGYPTLKYFKDGKEQFKYRGQRTKDALVDFMKSPSEQD 151
            V+ L   NF + ++K+K  LVMFYAPWC HCKK+ P     A    +   I    AAVDCVK  +  L  +  V GYPT  Y+  GK   KY   RT+    +++++  E D
Sbjct:  399 VLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIA--CAAVDCVKDKNQDLCQQEAVKGYPTFHYYHYGKFAEKYDSDRTELGFTNYIRALREGD 508

The following BLAST results are available for this feature:

BLAST of TCONS_00066944-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00066944-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
PDIA5	3.373e-42	41.35	Protein disulfide-isomerase A5 OS=Homo sapiens GN=...	[more]

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TCONS_00066944-protein (polypeptide) - C. hemisphaerica

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