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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00066865-protein ID=TCONS_00066865-protein|Name=TCONS_00066865-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1117bp
MPTTSTSKKVQQPLDSSLSKDGRFLDKLIELLHTPVKKYRQNKEAVPISP
QKSSSAKINHPTFEREAKLLKYFGTRYKEERVFSQSHYVDKFILIFQELI
KSRLCNRVWVENASPENYLRLFHCLRLLLRDPNFQNELHAYDGIRVIAEN
LKLFGDQYIVHGGDETLIDILKEIINICQKMSIEEHQRSIIVANEIHKTL
VLLLSSTSLVIIHLSTFALIALTKSDEAKIAVSELNVVERLLQIIGEFDS
TSKQVASTLLRQLCTVQEIKQQIRIYHGVPTLLSLLRSDAMKLLWNILCI
LVHLAEDTETSNMVRLLGGIPILVSLLQNRQYSYDDEVFDGSSSVRFKNN
DVTNLKSAVCAALTQLILNDTNARHLLQANGIYFVALQIFTKKSKDERNH
LKSNELQLQKNAFRTLRFMFSMERNRQLFKRIFPPDLFEIFIDVGHYQQE
LDAYDKLVQIFNQLPDEEIDVIKENVQAVNQNKEPIYHIQQYAVYEHLGS
GAFGSVYKVKKKGGQTFLAMKEISTHNTEFGKSARERNTNANGIINECIF
VKKQINHVNIVKYHKAFVEGDKLYIIMDLIDGAPLGEHFNALKEKQQMFS
EDRLWNIFIQIVLALRYIHKEKSIVHRDLTPNNIMLGEDYKVTITDFGLA
RQKNSDASKLTSMVGTIVYSCPEVVRGIEYGEKADIWAIGCILYQMACLE
PPFFSSNMLSLATKIVEGEYEELPDGLYDPLVSTVIQRCLTVKAEERPDI
IEVASLITDLLISHMEKLRMQTFDLERRLEKEKKRLQRHTDDMKNYHMSY
NSGSGKQKYDESFSEQESGATSDNQTDSSLPSSARSRQKSLTSNNIKYEE
SLTPATDDGGGGCRQFKSKPIKIQQRSDQRREIVSSSGSFEEDTEEDDLF
KKPSNLPRRLDPHQNNNNRRKFSQNDIHTEAVVDKMMNHVKRTQSCSYID
NLNALEKTPTKHRPTSAQTTLTISPRRVRVIDDPVLQMLTQLHKIIYITQ
LPPPMKIDATRRTIDQYKRSLFSAPSSALSLKNELKKLLEGSKEHVDIVS
PSLEGSGRFNTSLSNLNEQAIDASVTYEELKTMLETSLVNSGYYAHHPSS
PRVKPRLKLFSSKPTSQ Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005515 | protein binding |
| GO:0004672 | protein kinase activity |
| GO:0005524 | ATP binding |
| GO:0005488 | binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0005488 |
binding |
| molecular_function |
GO:0005515 |
protein binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 765..792 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 600..853
e-value: 1.5E-50
score: 171.1 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 472..599
e-value: 1.5E-20
score: 72.8 |
| None | No IPR available | PFAM | PF12330 | Haspin_kinase | coord: 499..655
e-value: 6.2E-6
score: 25.3 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 784..926 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1095..1117 |
| None | No IPR available | CDD | cd00020 | ARM | coord: 231..328
e-value: 6.02734E-8
score: 51.1611 |
| IPR000225 | Armadillo | SMART | SM00185 | arm_5 | coord: 225..265
e-value: 1.9
score: 17.5
coord: 307..368
e-value: 0.83
score: 18.7
coord: 266..306
e-value: 82.0
score: 6.1 |
| IPR000225 | Armadillo | PROSITE | PS50176 | ARM_REPEAT | coord: 318..381
score: 9.012 |
| IPR000719 | Protein kinase domain | PFAM | PF00069 | Pkinase | coord: 492..751
e-value: 3.3E-53
score: 180.6 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 492..761
score: 43.976 |
| IPR011989 | Armadillo-like helical | GENE3D | 1.25.10.10 | | coord: 275..471
e-value: 8.8E-14
score: 50.9
coord: 109..274
e-value: 4.0E-9
score: 35.6 |
| IPR008266 | Tyrosine-protein kinase, active site | PROSITE | PS00109 | PROTEIN_KINASE_TYR | coord: 624..636 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 498..521 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 479..768 |
| IPR016024 | Armadillo-type fold | SUPERFAMILY | 48371 | ARM repeat | coord: 114..464 |
Blast
BLAST of TCONS_00066865-protein vs. Swiss-Prot (Human)
Match: NEK10 (Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10 PE=2 SV=3) HSP 1 Score: 713.761 bits (1841), Expect = 0.000e+0 Identity = 368/742 (49.60%), Postives = 514/742 (69.27%), Query Frame = 0 Query: 66 EAKLLKYFGTRYKEERVFSQSHYVDKFILIFQELIKSRLCNRVWVENASPENYLRLFHCLRLLLRDPNFQNELHAYDGIRVIAENLKLFGDQYIVHGGDETLIDILKEIINICQKMSIEEHQRSIIVANEIHKTLVLLLSSTSLVIIHLSTFALIALTKSDEAKIAVSELNVVERLLQIIGEFDSTSKQVASTLLRQLCTVQEIKQQIRIYHGVPTLLSLLRSDAMKLLWNILCILVHLAEDTETSNMVRLLGGIPILVSLLQ-NRQYSYDDEVFDGSSSV-----------------RFKNNDVTNLKSAVCAALTQLILNDTNARHLLQANGIYFVALQIFTKKSKDERNHLKSNELQLQKNAFRTLRFMFSMERNRQLFKRIFPPDLFEIFIDVGHYQQELDAYDKLVQIFNQLPDEEIDVIKENVQAVNQNKEPIYHIQQYAVYEHLGSGAFGSVYKVKKKGGQTFLAMKEISTHNTEFGKSARERNTNANGIINECIFVKKQINHVNIVKYHKAFVEGDKLYIIMDLIDGAPLGEHFNALKEKQQMFSEDRLWNIFIQIVLALRYIHKEKSIVHRDLTPNNIMLGEDYKVTITDFGLARQKNSDASKLTSMVGTIVYSCPEVVRGIEYGEKADIWAIGCILYQMACLEPPFFSSNMLSLATKIVEGEYEELPDGLYDPLVSTVIQRCLTVKAEERPDIIEVASLITDLLISHMEKLRMQTFDLERRLEKEKKRLQRH 789
EA L+ F YK ER FS+ F IF L+K+RL +R WV A ++LR+ CLRLL+RDP +Q LH+ GI +A+ +++ ++Y+ +G ++ +D L + I QK++ + QR + + HKTLV LL + ++ S AL +L +S E + +SELN+VE LL I+ E+D SK++ + LLR LC ++K+Q+++Y G+P LLSLL SD +KLLW+I+ ILV + ED ETS +R+ GGI L+ +LQ +R + D SS R + +L++A CAALT+L+LNDTNA ++Q NG+Y +A I K K N KSN LQ AFR LRF+FSMERNR LFKR+FP DLFEIFID+GHY +++ AY++LV N L ++E+ I EN++++NQNK P+ +I YA+ +HLGSGAFG VYKV+K GQ LAMKE++ HN FGK ++R+++ I++E +K+Q+ H NIV+Y+K F+E D+LYI+M+LI+GAPLGEHF++LKEK F+E+RLW IFIQ+ LALRY+HKEK IVHRDLTPNNIMLG+ KVT+TDFGLA+QK + SKLTS+VGTI+YSCPEV++ YGEKAD+WA+GCILYQMA L PPF+S+NMLSLATKIVE YE +P+G+Y V+ I RCLT AE RPDI+EV+S+I+D+++ +++ L LE++LE+E++R QR+
Sbjct: 80 EAVELENFSINYKNERNFSKHPQRKLFQEIFTALVKNRLISREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGIENLAQYMEIVANEYLGYGEEQHTVDKLVNMTYIFQKLAAVKDQREWVTTSGAHKTLVNLLGARDTNVLLGSLLALASLAESQECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCAEPQVKEQVKLYEGIPVLLSLLHSDHLKLLWSIVWILVQVCEDPETSVEIRIWGGIKQLLHILQGDRNFVSDHSSIGSLSSANAAGRIQQLHLSEDLSPREIQENTFSLQAACCAALTELVLNDTNAHQVVQENGVYTIAKLILPNKQK---NAAKSNLLQCY--AFRALRFLFSMERNRPLFKRLFPTDLFEIFIDIGHYVRDISAYEELVSKLNLLVEDELKQIAENIESINQNKAPLKYIGNYAILDHLGSGAFGCVYKVRKHSGQNLLAMKEVNLHNPAFGKDKKDRDSSVRNIVSELTIIKEQLYHPNIVRYYKTFLENDRLYIVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVTDFGLAKQKQEN-SKLTSVVGTILYSCPEVLKSEPYGEKADVWAVGCILYQMATLSPPFYSTNMLSLATKIVEAVYEPVPEGIYSEKVTDTISRCLTPDAEARPDIVEVSSMISDVMMKYLDNLSTSQLSLEKKLERERRRTQRY 815 HSP 2 Score: 95.9005 bits (237), Expect = 6.133e-20 Identity = 56/138 (40.58%), Postives = 82/138 (59.42%), Query Frame = 0 Query: 967 AQTTLTISPRRVRVIDDPVLQMLTQLHKIIYITQLPPPMKIDATRRTIDQYKRSLFSAPSSALSLKNELKKLLEGSKEHVD----IVSPSLEGSGRFNTSLSNLNEQAIDAS------VTYEELKTMLETSLVNSGYY 1094
A + +S R+VR I DP+ Q+L QLHKIIYITQLPP + + RR I+++K+SLFS S+ +LK+E+KKL +GS E ++ L SLS + + S +TYE+++T++E L SGYY
Sbjct: 1014 ASAGIAVSQRKVRQISDPIQQILIQLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKLSQGSPEPIEPNFFTADYHLLHRSSGGNSLSPNDPTGLPTSIELEEGITYEQMQTVIEEVLEESGYY 1151
The following BLAST results are available for this feature:
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