Sequence
The following sequences are available for this feature:
polypeptide sequence
>TCONS_00066671-protein ID=TCONS_00066671-protein|Name=TCONS_00066671-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1588bp MSRSVVTGNDSGLPSPRRRYKWHHIVVSILCVCALAGVVSSLFTTINSIH NMKKKRSLDKREISKRSVEISNDTGVDSSGNDQSFNVMEINQSINDQPKN LTSNRTIDEIVPGIARNTSVVEATLLAGNATRSNMTEEAVESEFESGSDS DEVDDTSSGASSDQVDSIDSTSNAGSSASETTDTEKNSSTESVKSTETSK TETIKPNQESAVKSPKVTKIDALKPVPNTSQPTAKTAQHQNVNLSKPQNQ APLTNPRLTSPVIANKLTGKRKYNETDSLVHQEASNSTEDSTEMVVESQI SDASSGDDEVDDDTESSSDGESSTKQPEVESHDLTKQVTPESTKPKVSKP KVPLSNQAIQTNSSNSTNTASQSVNTAQQIRPAILSTSIQQQSQSAKAMA QPNPIKPSQTQKQPLTSANTNAKLSQAISAAQISKNKNPVSSQQTTLVSE SDVDSPPKETATNSSTDQQQTVQQKPQTSSPQIQNEGLHLTPIKNKFHFA NQTVTESVRNTTSSLYEPTATRSEKTTSTRTQSSSSPTTEARNINEDHKE KPKEDDYPSFPTNYHASGIIILPESKIAEPFEIWYSQDQKKSRIDYYYGN DKTFQRGDQGDYGISYKYVPMFNDQQKNFDGCYTITGTPNRRIIAQVITP NMTWFKYNKTEVYTGVLTTKWTYKYTAYGMKNYQSVWVTKSKPYRPIRYE MFGFDMMLGSYYDNYVINYVSFEEWTPTDNVFVMPQGIQCSKWSNSLESS LIVNPMQEFTAFRAEDALDHSQRYSEFKEKHYKNKGHPHDADKRKHVFKH NARYIHSHNRRNLSFKLKPNMFADKFDKELEHFHGALEKDTRNHEGVKEF HKIDNVKTSSHPPDQNIPEELDWRDYGAVSSVSGQGICGSCYAFSAAEAV EGAWYRKTSKMVRLSKQQLVDCSWGFGNHGCKGGHYAAALSWVYVHGIST AKSYGKYLGQEGYCHFNDTWFGANIEGFTYVPIWNATALKRAITNHGPVA VSINTLPLSFKFYGKGIYNDPKCSKNMTTHSALVIGYGKENGQEYWIVKN SWSALWGENGYIRVAMKDDLCGITEYPVAVIVKHPSFHLPVGMKNVKNNK EDDENEEEVEDKIPNDGKISSEVGKNIPLDPSGTNKKPKKQMPGNLDNDD VTKQSPNDDQQEDEDEKEEKKQKQSHKKMLEQYRLKEHEHETSMFEKTLQ QVEIPFKGLHIEDIGNDIKKIHELLVNTAEADKAFANNDNDKKKSHTGSH GDLSDVHPVNTESRKTGKSGQRVTSKNTKIRNKAQVSSPARPAFGTSNQG TNKPKNKKKLSKDTPKQTKNTTKTKKKQRQKMEIKKEFNDLIKNLDTKNE ATKSAIKKPSVTNTNNLKTNPKILNPEKIGSLSHSAKRSKTVRPTKSDRG SKRTTISRLDKKQRLNRQQRISKKNSQKITKKSLRKNSTKRSKSSGRYIS KSNDYXTKKSKSSGRYISKSNDYLPYATPVRRTMDIHFIGAPSSNIDHYL LKEHQNLRKEFKSKRKNISKRRKSGRMATSHKRERIQQQSAMDIAKQDSM DSLYSFINKKVQEYTSTQVEPAKKRDMNYYKHHIHNGK Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following
gene feature:
This polypeptide derives from the following
transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term Definition
GO:0006508 proteolysis
Vocabulary: Molecular Function
Term Definition
GO:0008234 cysteine-type peptidase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category
Term Accession
Term Name
biological_process
GO:0006508
proteolysis
molecular_function
GO:0008234
cysteine-type peptidase activity
InterPro
Analysis Name:
InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
200 400 600 800 1000 1200 1400 Score = Score = Expect = 1.7E-87 / Score = 293.4 Expect = 1.49524E-91 / Score = 295.687 Score = Score = 58.0 Score = 43.56 Score = 79.08 Expect = 4.3E-79 / Score = 278.8 Expect = 2.3E-63 / Score = 214.1 Expect = 2.1E-6 / Score = 37.2 Expect = 2.1E-6 / Score = 28.0 Score = Score = Sequence Coil Coil G3DSA:3.90.70.10 cd02248 SSF54001 PR00705 SM00645 PF00112 SM00848 PF08246 PS00139 PS00640
IPR Term IPR Description Source Source Term Source Description Alignment
None No IPR available COILS Coil Coil coord: 1501..1521
None No IPR available COILS Coil Coil coord: 1157..1186
None No IPR available GENE3D 3.90.70.10 coord: 767..1090 e-value: 1.7E-87 score: 293.4
None No IPR available CDD cd02248 Peptidase_C1A coord: 868..1080 e-value: 1.49524E-91 score: 295.687
None No IPR available SUPERFAMILY 54001 Cysteine proteinases coord: 770..1081
IPR000668 Peptidase C1A, papain C-terminal PRINTS PR00705 PAPAIN coord: 1030..1040 score: 43.56 coord: 1045..1051 score: 79.08 coord: 885..900 score: 58.0
IPR000668 Peptidase C1A, papain C-terminal SMART SM00645 pept_c1 coord: 867..1081 e-value: 4.3E-79 score: 278.8
IPR000668 Peptidase C1A, papain C-terminal PFAM PF00112 Peptidase_C1 coord: 867..1080 e-value: 2.3E-63 score: 214.1
IPR013201 Cathepsin propeptide inhibitor domain (I29) SMART SM00848 Inhibitor_I29_2 coord: 774..830 e-value: 2.1E-6 score: 37.2
IPR013201 Cathepsin propeptide inhibitor domain (I29) PFAM PF08246 Inhibitor_I29 coord: 774..829 e-value: 2.1E-6 score: 28.0
IPR000169 Cysteine peptidase, cysteine active site PROSITE PS00139 THIOL_PROTEASE_CYS coord: 885..896
IPR025661 Cysteine peptidase, asparagine active site PROSITE PS00640 THIOL_PROTEASE_ASN coord: 1045..1064
Blast
BLAST of TCONS_00066671-protein vs. Swiss-Prot (Human)
Match:
CATL2 (Cathepsin L2 OS=Homo sapiens GN=CTSV PE=1 SV=2)
HSP 1 Score: 181.415 bits (459), Expect = 2.997e-50
Identity = 115/318 (36.16%), Postives = 165/318 (51.89%), Query Frame = 0
Query: 773 RYSEFKEKHYKNKGHPHDADKRKHVFKHNARYIHSHN----RRNLSFKLKPNMFADKFDKELEHFHGALEKDTRNHEGVKEFHKIDNVKTSSHPPDQNIPEELDWRDYGAVSSVSGQGICGSCYAFSAAEAVEGAWYRKTSKMVRLSKQQLVDCSWGFGNHGCKGGHYAAALSWVYVH-GISTAKSYGKYLGQEGYCHFNDTWFGANIEGFTYVPIWNATALKRAITNHGPVAVSINTLPLSFKFYGKGIYNDPKCSKNMTTHSALVIGYGKE----NGQEYWIVKNSWSALWGENGYIRVAM-KDDLCGI---TEYP 1077
++ ++K H + G ++ R+ V++ N + I HN + F + N F D ++E G RN K K P ++P+ +DWR G V+ V Q CGSC+AFSA A+EG +RKT K+V LS+Q LVDCS GN GC GG A A +V + G+ + +SY Y+ + C + AN GFT V AL +A+ GP++V+++ SF+FY GIY +P CS H LV+GYG E N +YW+VKNSW WG NGY+++A K++ CGI YP
Sbjct: 28 KWYQWKATHRRLYG-ANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCF----RNQ-------KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESY-PYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYP 332
The following BLAST results are available for this feature: